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Phase separation of a master transcription factor targeted by a natural compound regulates fungal ergosterol homeostasis Huiyuan WangYuhua WangZhonghua Ma Research Paper 12 June 2025
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Targeting ARID1A: the key to dominating the differentiation fate of germinal center B cells Yehui ZhangYuwei DiaoChun Hu Research Highlight 11 June 2025
m6A-REFII: an antibody-independent tool for in situ visualizing cellular specific RNA m6A compatible with protein immunofluorescence staining Yujie MiChenyang HuangJianzhao Liu Research Paper 11 June 2025
Engineered exosomal miR140 modulates mitophagy of chondrocytes through targeting CAPN1 to alleviate osteoarthritis Yuan LiuKai HuangBin Shen Research Paper 10 June 2025
Berberine dissociates mitochondrial complex I by SIRT3-dependent deacetylation of NDUFS1 to improve hepatocellular glucose and lipid metabolism Xuekai WangHu LiZonggen Peng Research Paper 06 June 2025
Functional cancer-cell-nociceptive neuronal circuits drive gastric tumor progression Peng GaoJie ZhangYicheng Chen Research Highlight 05 June 2025
Non-negligible role of gut morphology in shaping mammalian gut microbiomes Yixin LiuGuangping HuangYibo Hu Research Paper 05 June 2025
Endocrine cancer organoids in basic and translational medical research Dong ChenZhulan ChenYongsheng Zhao Review Open access 05 June 2025
Bioprofiling and vaccine development for Zika virus Huiping ShiShengyong FengYuanyu Huang Review 03 June 2025
Peripheral blood RNA modifications as a novel diagnostic signature for polycystic ovary syndrome Liwen ZhangXinxin LiuZi-Jiang Chen Research Paper 03 June 2025
Multi-omics study reveals a light-dependent regulatory network of flavonoid biosynthesis in lettuce (Lactuca sativa L.) Yuting XiangShuxin ZhengYang Zhang Research Paper 30 May 2025
Therapeutic hypothermia for acute ischemic stroke: from preclinical studies to clinical trials Xi ChenJin XuDi Wu Review 30 May 2025
N6-methyladenosine reader YTHDF3-mediated CEBPA translation maintains genomic stability and stem cell function to prevent liver injury Yaxu LiangWeiwei YuXiang Zhong Research Paper 30 May 2025
CCR5-mediated dynamic maintenance of resident memory T cells in the respiratory tract Tiange ShaoJiacheng YaoHai Qi Research Paper 30 May 2025
GMNN mutations cause female infertility characterized by preimplantation embryo arrest through regulating DNA re-replication Honghui ZhangWei SuZi-Jiang Chen Research Paper 29 May 2025
Role of multi-omics in aquaculture genetics and breeding: current status and future perspective Xiaofei YuSara FaggionZhenmin Bao Review 28 May 2025
Conservation epigenomics: integrating epigenetic mechanisms into species conservation Yisi HuWenliang ZhouFuwen Wei Insight 27 May 2025
Unraveling the diversity of bile acid modifications by integrative mass spectrometry approaches Nan XingYu-Fei WangWan-Yang Sun Insight 27 May 2025
Effects of NGF-chitosan on alleviating secondary degeneration and repairing primary degeneration after expanded partial optic nerve transection Xiao LiuHongmei DuanWang Jia Research Paper 27 May 2025
Genomic and chromosomal architectures underlying fertility maintenance in the testes of intergeneric homoploid hybrids Li RenYiyan ZengShaojun Liu Research Paper 23 May 2025
Exposure to the prenatal enriched environment alters maternal gut microbiota and promotes embryonic neurodevelopment via activating the AHR-Src pathway Yuhan LiuChenna HuangXuekun Li Research Paper 23 May 2025
Pluripotent stem cell-derived cardiomyocyte transplantation: marching from bench to bedside Yi HongJiarui LiuKai Wang Review 23 May 2025
Embryonic mast cells arise from the Cpa3-expressing precursors but not granulocyte-monocyte progenitors Wei MaHuifang ChenBing Su Research Paper 22 May 2025
Mutual regulation between cell cycle and transcription termination factor TTF2 Yuying HuLele XuQimin Zhan Research Paper 22 May 2025
Bisulfite-free whole-genome mapping of 5-methylcytosine at single-base resolution by NTD-seq Min WangNeng-Bin XieBi-Feng Yuan Research Paper 22 May 2025
Unique structures and functions of ATP-binding cassette type H transporters Qing X. Li Research Highlight 21 May 2025
High-quality reference genome and population analysis of allotetraploid Elymus sibiricus provide insight into genome origin and environmental adaptations to the Qinghai-Tibetan Plateau Xinrui LiChangbing ZhangShiqie Bai Research Paper 21 May 2025
An FBP1-regulated metabolic switch reverses liver senescence and drives hepatocellular carcinoma progression Yi ZhangXinyue ZhangZhaojian Gong Research Highlight 16 May 2025
Evolutionary repeatability of chromatin accessibility in the hippocampus between echolocating bats and soft-furred tree mice Luye ShiYuanshuo MaPeng Shi Research Paper 15 May 2025
Single-cell sequencing and spatial transcriptomics reveal FAS+ T cell and autophagy-related signatures predicting chemoimmunotherapy response in diffuse large B-cell lymphoma patients Ning LouLiyuan DaiXiaohong Han Research Paper 15 May 2025
From gaps to insights: telomere-to-telomere cotton genome deciphers centromere dynamics after polyploidization Zhaoen YangFuguang Li Research Highlight 08 May 2025
A strategy for the development of receptor-containing antibodies targeting malaria variant surface antigens Yizhuo WangHengfang TangJunfeng Wang Letter to the Editor 08 May 2025
VPS35/Retromer-dependent MT1-MMP regulation confers melanoma metastasis Qinggang HaoYan BaiJianwei Sun Research Paper 08 May 2025
Weakened priming effect along soil profile in alpine grasslands on the Tibetan Plateau Mei HeKai FangYuanhe Yang Research Paper 08 May 2025
Olfactory GnRH3 crypt sensory neurons transduce sex pheromone signals to induce male courtship behavior in zebrafish Xuefan CuiLu ChenWei Hu Research Paper 08 May 2025
Downregulation of METTL3 enhances TRADD-mediated apoptosis in inflammatory bowel disease Tingyue GongZhiyang ZengMing Zhong Research Paper 08 May 2025
Transcriptomic evidence from peripheral blood reveals nonlinear gene expression trajectories of aging in female rhesus macaques Chong-Jun WengLong-Bao LvQing-Peng Kong Letter to the Editor 07 May 2025
Glutaminolysis and α-ketoglutarate-stimulated KCa3.1 expression contribute to β-adrenoceptor activation-induced myocardial fibrosis in mice Ru-Yue BaiLin-Hong WuXiu-Ling Deng Research Paper 07 May 2025
Inhibition of recurrence and metastasis in triple-negative breast cancer through nanoparticle-mediated silencing of LPCAT1 to remodel ATP energy metabolism Xiuling LiSenlin LiPhei Er Saw Research Paper 07 May 2025
Targeting tRNA methyltransferases: from molecular mechanisms to drug discovery Yanrong GaoXinyu LiuJiazhi Li Review 07 May 2025
Chemical reprogramming of liver cancer cells through targeting Aurora kinases Yunfei BaiQian LiuBiao Liu Letter to the Editor 24 April 2025
Structure-based principles underlying ligand recognition of xanthine-II riboswitch Xiaochen XuMengqi HeAiming Ren Research Paper Open access 24 April 2025
m6A deficiency impairs uterine spiral artery remodeling to induce preeclampsia-like symptoms via FGF2 Sun LiuWenqian ChenLaixin Xia Research Paper 24 April 2025
Rice genetic variations provide information on the potential to reduce thiamin deficiencies Teresa B. FitzpatrickSimon StrobbeMaria Faustino Research Highlight 23 April 2025
PanSci: decoding panoramas of ageing Yalan LiaoMingguo QiuYan-Jiang Wang Research Highlight 23 April 2025