From gaps to insights: telomere-to-telomere cotton genome deciphers centromere dynamics after polyploidization Zhaoen YangFuguang Li Research Highlight 08 May 2025
A strategy for the development of receptor-containing antibodies targeting malaria variant surface antigens Yizhuo WangHengfang TangJunfeng Wang Letter to the Editor 08 May 2025
VPS35/Retromer-dependent MT1-MMP regulation confers melanoma metastasis Qinggang HaoYan BaiJianwei Sun Research Paper 08 May 2025
Weakened priming effect along soil profile in alpine grasslands on the Tibetan Plateau Mei HeKai FangYuanhe Yang Research Paper 08 May 2025
Olfactory GnRH3 crypt sensory neurons transduce sex pheromone signals to induce male courtship behavior in zebrafish Xuefan CuiLu ChenWei Hu Research Paper 08 May 2025
Downregulation of METTL3 enhances TRADD-mediated apoptosis in inflammatory bowel disease Tingyue GongZhiyang ZengMing Zhong Research Paper 08 May 2025
Transcriptomic evidence from peripheral blood reveals nonlinear gene expression trajectories of aging in female rhesus macaques Chong-Jun WengLong-Bao LvQing-Peng Kong Letter to the Editor 07 May 2025
Glutaminolysis and α-ketoglutarate-stimulated KCa3.1 expression contribute to β-adrenoceptor activation-induced myocardial fibrosis in mice Ru-Yue BaiLin-Hong WuXiu-Ling Deng Research Paper 07 May 2025
Inhibition of recurrence and metastasis in triple-negative breast cancer through nanoparticle-mediated silencing of LPCAT1 to remodel ATP energy metabolism Xiuling LiSenlin LiPhei Er Saw Research Paper 07 May 2025
Targeting tRNA methyltransferases: from molecular mechanisms to drug discovery Yanrong GaoXinyu LiuJiazhi Li Review 07 May 2025
Chemical reprogramming of liver cancer cells through targeting Aurora kinases Yunfei BaiQian LiuBiao Liu Letter to the Editor 24 April 2025
Structure-based principles underlying ligand recognition of xanthine-II riboswitch Xiaochen XuMengqi HeAiming Ren Research Paper Open access 24 April 2025
m6A deficiency impairs uterine spiral artery remodeling to induce preeclampsia-like symptoms via FGF2 Sun LiuWenqian ChenLaixin Xia Research Paper 24 April 2025
Rice genetic variations provide information on the potential to reduce thiamin deficiencies Teresa B. FitzpatrickSimon StrobbeMaria Faustino Research Highlight 23 April 2025
PanSci: decoding panoramas of ageing Yalan LiaoMingguo QiuYan-Jiang Wang Research Highlight 23 April 2025
Flooding followed by drought in urban and forest soils: unraveling microbial dynamics and ecological functions Yilong HaoYifang ZhangQing-Lin Chen Letter to the Editor 23 April 2025
The Yr9 gene encoding a CC-NBS-LRR protein in the 1RS-1BL translocation confers wheat stripe rust resistance Chunhui WangYanan ChangFangpu Han Letter to the Editor 22 April 2025
Wheat stripe rust resistance gene Yr9, derived from rye, is a CC-NBS-LRR gene in a highly conserved NLR cluster Yang YuJiajun LiuJiajie Wu Letter to the Editor 22 April 2025
Maternal transcription factor OTX2 directly induces SETD1A and promotes embryonic genome activation in human pre-implantation embryos Tianlei ZhangZiyan PengGe Lin Research Paper 22 April 2025
Attenuation of plant immune kinases by U-box type E3 ubiquitin ligases Hui TaoYuese NingRuyi Wang Research Highlight 11 April 2025
Development of regenerative therapies targeting fibrotic endometrium in intrauterine adhesion or thin endometrium to restore uterine function Guangfeng ZhaoJianwu DaiYali Hu Review 11 April 2025
Priming crops for heat stress with prime editing Karla GaspariniAgustin Zsögön Research Highlight 09 April 2025
Advances in the chemical synthesis of human proteoforms Ziyi YangYudi XiaoLei Liu Review 08 April 2025
Gut microbes-muscle axis in muscle function and meat quality Yiwen HeHong HuXihong Zhou Review 08 April 2025
Metabolome genome-wide association analyses identify a splice mutation in AADAT affects lysine degradation in duck skeletal muscle Dapeng LiuWenlei FanZhengkui Zhou Research Paper 07 April 2025
Animal burrows as critical thermal refuges in the age of climate change Song SunErick J. LundgrenYuanwen Kuang Letter to the Editor 03 April 2025
Genetic mutations across multiple pathways drive filamentous growth and virulence in the emerging fungal pathogen Candida auris Chao LiShuaihu LiGuanghua Huang Letter to the Editor 03 April 2025
Integrating genomic features for prognosis in Chinese patients with B-cell lymphoma following chimeric antigen receptor T-cell therapy Linghui ZhouYouqin FengYongxian Hu Research Paper 03 April 2025
Unveiling the clinical significance of RNA pseudouridine in colorectal cancer Jiehua LiXuanfei LiXiang Zhou Research Paper 03 April 2025
Cucumber green mottle mosaic virus encodes additional small proteins with specific subcellular localizations and virulence function Pan GongMengxin GaoFangfang Li Research Paper 01 April 2025
Two competing guilds as barometers of host health Haohan MaKai WangChangtao Jiang Research Highlight 27 March 2025
Conservation medicine: a “Unity of Nature and Man” perspective Yifei XuYang LiFuwen Wei Insight 27 March 2025
Transcription factor addictions: exploring the potential Achilles’ Heel of endometriosis Yang YangYi DuShengtao Zhou Review 27 March 2025
Does caudate lobe resection really improve the surgical outcomes of patients with hilar cholangiocarcinoma? A multicenter retrospective study Ran TaoTong YuanShuai Xiang Research Paper 27 March 2025
CRISPR screening identifies protein methylation and ubiquitination modifications that modulate aflatoxin B1 cytotoxicity Huaqiang YangXi JiZhenfang Wu Research Paper 27 March 2025
Extracellular vesicles in cancer progression: mechanisms and significance Ying GaoDenghui WeiTiebang Kang Review 25 March 2025
RIG-I-driven CDKN1A stabilization reinforces cellular senescence Cui WangXiaoyu JiangWeiqi Zhang Research Paper 24 March 2025
Cracking the chitin code: how a single pair of LysM receptors deciphers symbiosis and immunity in Marchantia Karen VelandiaEloise Foo Research Highlight 21 March 2025
Integrative analysis based on CRISPR screen identifies apilimod as a potential therapeutic agent for cisplatin-induced acute kidney injury treatment Yunpeng ChuMuyun WeiShengying Qin Research Paper 21 March 2025
Developing a robust genome editing tool based on an endogenous type I-B CRISPR-Cas system in Saccharopolyspora spinosa Wenfang WangHuiyan HeYinhua Lu Research Paper 21 March 2025
Natural resistance to cancers in long-lived mammals: genomic mechanisms and experimental evidence to explain Peto’s paradox Linxia SunZhikang XuShixia Xu Research Paper 21 March 2025
An early microbial landscape: inspiring endeavor from the China Space Station Habitation Area Microbiome Program (CHAMP) Junxia YuanJinlu YangWenyu Shi Cover Article 20 March 2025
Lactobacillus johnsonii-derived leucic acid promotes fatty acid absorption and deposition by targeting CD36 Yunxia LiZhiming ZhangJie Yin Research Paper 19 March 2025
Evolution of sexual dimorphism in nonhuman primates Yuan-Ting GuoYijun YangXiao-Guang Qi Insight 17 March 2025
The immuno-metabolic trade-off: a driver of metabolic disorders and aging Juanhong LiuQinlei HuangFeng Liu Insight 17 March 2025
Genomic insights into the brooding reproduction and climate-driven dynamics of Pocillopora damicornis in the Anthropocene Jie LiYali LiuQiang Lin Letter to the Editor 17 March 2025
A tango between NSUN2 and TET2: defining both the fate and origin of RNA Tianbao ShangLu LiuLi Tan Research Highlight 12 March 2025
