Handbook of Experimental Pharmacology

Voltage-gated Sodium Channels: Structure, Function and Channelopathies

Editors: Chahine, Mohamed (Ed.)

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  • Reviews exhaustively the key recent research into Na+ channels and related diseases
  • Broadens our understanding on Na+ channels and their associated diseases
  • Summarizes the latest studies on the physiopathology of Na+ channels
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  • ISBN 978-3-319-90284-5
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Hardcover $179.99
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About this book

This book provides a timely state-of-the-art overview of voltage-gated sodium channels, their structure-function, their pharmacology and related diseases. Among the topics discussed are the structural basis of Na+ channel function, methodological advances in the study of Na+ channels, their pathophysiology and drugs and toxins interactions with these channels and their associated channelopathies.

About the authors

Dr. Mohamed Chahine is a Professor at the Department of Medicine of Université Laval and Head of the Laboratory of Cellular Electrophysiology at the CERVO Brain Research Center of the Institut universitaire en santé mentale de Québec. He has published over 160 articles in refereed journals as well as several book chapters in the field of voltage-gated Na+ channels and related diseases. Dr. Chahine has served or is currently serving on various committees of the Canadian Institutes of Health Research and the Heart and Stroke Foundation of Canada. He is associate editor of Frontiers Journal and editor of Scientific Reports. He is a member of the editorial boards of the Canadian Journal of Cardiology (Canada), the World Journal of Cardiology (China), the Journal of Cardiovascular Research (USA), Advances in Bioscience and Biotechnology (USA), and the Journal of Cardiology and Therapy (Hong Kong). He has also organized several national and International symposia and workshops on the role of ion channels in disease. Dr. Chahine has been invited to present his research at several national and international conferences and academic institutions.

Table of contents (19 chapters)

Table of contents (19 chapters)
  • Evolutionary History of Voltage-Gated Sodium Channels

    Nishino, Atsuo (et al.)

    Pages 3-32

  • Mining Protein Evolution for Insights into Mechanisms of Voltage-Dependent Sodium Channel Auxiliary Subunits

    Molinarolo, Steven (et al.)

    Pages 33-49

  • Structural and Functional Analysis of Sodium Channels Viewed from an Evolutionary Perspective

    Gamal El-Din, Tamer M. (et al.)

    Pages 53-72

  • The Cardiac Sodium Channel and Its Protein Partners

    Balse, Elise (et al.)

    Pages 73-99

  • Posttranslational Modification of Sodium Channels

    Pei, Zifan (et al.)

    Pages 101-124

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-3-319-90284-5
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-3-319-90283-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Voltage-gated Sodium Channels: Structure, Function and Channelopathies
Editors
  • Mohamed Chahine
Series Title
Handbook of Experimental Pharmacology
Series Volume
246
Copyright
2018
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG, part of Springer Nature
eBook ISBN
978-3-319-90284-5
DOI
10.1007/978-3-319-90284-5
Hardcover ISBN
978-3-319-90283-8
Series ISSN
0171-2004
Edition Number
1
Number of Pages
X, 450
Number of Illustrations
25 b/w illustrations, 55 illustrations in colour
Topics