Does acute stress induced via cold water immersion increase blood THC concentrations in regular cannabis users? Danielle McCartneyJordan LevouxIain S. McGregor Original Investigation Open access 14 June 2025
Ginsenoside Rg1 alleviates PCPA-induced insomnia by inhibiting NLRP3 inflammasome activation and pyroptosis through the Nrf2/HO-1 pathway in mice Jingyi LiXiufeng WangJunshan Huang Original Investigation Open access 10 June 2025
Effects of nicotine-alcohol co-use on alcohol-induced blackouts and other alcohol-related consequences in college students Veronica L. RichardsKimberly A. MallettMichael A. Russell Original Investigation 10 June 2025
A single intake of flavanol-rich cocoa improves inhibitory executive process under cognitive fatigue during aerobic exercise in men: a randomized, double-blind, placebo-controlled crossover trial Hayato TsukamotoSota YoneyaTakeshi Hashimoto Original Investigation Open access 10 June 2025
Alternating self-administration sessions of cocaine and heroin impact drug-related motivation and vocalisations in rats Kristian AdamatzkyAngharad C. CollinsBryan F. Singer Original Investigation Open access 09 June 2025
Comment on Zabik et al. (2024): timing and dosage effects of THC in fear extinction: challenges and feasibility in a clinical setting Ellen BarnerAlex CorbettLuke J. Ney Commentary 07 June 2025
Aggression is not blind: dominance and social history modulate murine responses to social instigation Tomoya NagaiAki Takahashi Original Investigation Open access 04 June 2025
Radixin in the nucleus accumbens core modulates amphetamine-induced locomotor activity based on context association Wen Ting CaiMyung Ji KwakJeong-Hoon Kim Original Investigation 03 June 2025
Bidirectional modulation of reward-guided decision making by dopamine Ana Antonia Dias MaileTheo O. J. GruendlerGerhard Jocham Original Investigation Open access 29 May 2025
Prenatal and early postnatal cannabis exposure interactions with adolescent chronic stress on anxiety-like, depression-like, and risk-taking behaviour Colleen S. PetersonIjeoma IfionuStephanie L. Borgland Original Investigation Open access 29 May 2025
High-fat Fructose diet induces neuroinflammation and anxiety-like behaviors by modulating liver-brain axis communication Hongmei DuYuan ZhouMing Chen Original Investigation 28 May 2025
Adolescent female rats are resistant to the affective and cognitive impacts of Δ9-tetrahydrocannabinol exposure despite long-lasting molecular and neuronal disturbances in the hippocampal-hypothalamic network Marta De FeliceHanna J. SzkudlarekSteven R. Laviolette Original Investigation 28 May 2025
Resveratrol mitigates activated astrocytes and microglia preventing Alzheimer’s Disease (AD) progression and facilitates neuronal communication in Amyloid-β25–35 induced rat model for AD: A special emphasis on non-neuronal involvement in AD pathophysiology Kumar SuryaAnitha RathinamMuthuswamy Anusuyadevi Original Investigation 27 May 2025
D2 receptor activation modulates NMDA receptor antagonist-enhanced high-frequency oscillations in the olfactory bulb of freely moving rats Jacek WróbelDaniel Krzysztof WójcikMark Jeremy Hunt Original Investigation Open access 27 May 2025
Endocannabinoid modulation of defensive state transitions to innate and learned threat Niharika LoombaAnyu CaoSachin Patel Original Investigation Open access 24 May 2025
Telmisartan mitigates behavioral and cytokine level alterations but impairs spatial working memory in a phencyclidine-induced mouse model of schizophrenia Ana Carolina Dutra-TavaresJulyana Gomes MaiaYael Abreu-Villaça Original Investigation 23 May 2025
Dose-extending placebo effect in a rat model of buprenorphine maintenance treatment Kayla M. PittsEmma M. PilzJonathan J. Chow Original Investigation Open access 21 May 2025
Early maternal separation potentiates the impact of later social isolation in inducing depressive-like behavior via oxidative stress in adult rats Yating ChenJingjing DuBo Zhang Original Investigation 20 May 2025
Preconceptual paternal ethanol drinking induces sexually dimorphic behavioural changes across 2 generations Sahir HussainDarren DayBart A. Ellenbroek Original Investigation Open access 20 May 2025
Xanthouhumol relieves stress-induced depressive-like behaviors through the Sirt1/NF-κB/NLRP3 pathway Gangqiang LinYi ZhangPeng Xie Original Investigation 20 May 2025
Xylazine potentiates the interoceptive effects of fentanyl in male and female rats Brooke N. BenderJoseph M. CarewJoyce Besheer Original Investigation 19 May 2025
Sildenafil promotes dual memory effects in young rats: involvement of dopamine reuptake Maria Florencia ConstantinEmilce Artur de la VillarmoisMariela Fernanda Pérez Original Investigation 19 May 2025
Correction to: Incremental efficacy systematic review and meta-analysis of psilocybin-for-depression RCTs Nicholas C. BorgognaTyler OwenBenjamin D. Hill Correction Open access 17 May 2025
The role of the endocannabinoid system in the interplay of adverse childhood experiences and interleukin 6 in individuals with borderline personality disorder Jennifer SpohrsValentin KühnleBirgit Abler Original Investigation Open access 17 May 2025
Psychedelic-like effects induced by 2,5-dimethoxy-4-iodoamphetamine, lysergic acid diethylamide, and psilocybin in male and female C57BL/6J mice Shelby A. McGriffJacquelin C. HeckerGrant C. Glatfelter Original Investigation Open access 17 May 2025
The interaction between finasteride and corticosterone levels: implications for depression-, and anxiety-like behavior and hippocampal synaptic plasticity in male rats Jose NayanaByrathnahalli S. Shankaranarayana RaoBettadapura N. Srikumar Original Investigation 16 May 2025
The serum levels of polyunsaturated fatty acids contribute to the antidepressant-like effects of 18β-Glycyrrhetinic acid in mice Wanzhao DingMaohua YaoJi-chun Zhang Original Investigation 15 May 2025
The link between tobacco smoking and susceptibility to misinformation Michal PiksaMagdalena ZaniewskaRafal Rygula Original Investigation Open access 15 May 2025
Chronic administration of methocinnamox, a mu-opioid receptor antagonist, reduces hedonic response without impacting motivation in mice Misbah SheikhEmily CambreSarah E. Canetta Original Investigation 10 May 2025
A Mechanistic study assessing difficulty discontinuing chronic hypnotic use Timothy RoehrsGail KoshorekThomas Roth Original Investigation 09 May 2025
(R)-ketamine induces mGlu5 receptor-dependent antidepressant-like effects in the chronic unpredictable mild stress model of depression in mice Agnieszka Pałucha-PoniewieraAnna Rafało-UlińskaKatarzyna Kaczorowska Original Investigation Open access 08 May 2025
A systematic review and meta-analysis of the acute effect of caffeine on attention Kasper KløveAnders Petersen Review 07 May 2025
Depression of intracranial self-stimulation in male and female rats by intraperitoneal lactic acid: effects of morphine, ketoprofen, and interactions with G-protein biased kappa opioid agonists Thomas J. MartinConner W. MartinSara R. Jones Original Investigation Open access 06 May 2025
Low to moderate doses of 3-methylmethcathinone (3-MMC) produce analgesic effects in healthy volunteers: a proof of principle study with a designer drug Johannes G RamaekersJohannes T ReckwegEef L Theunissen Original Investigation Open access 01 May 2025
Senegenin ameliorates diabetic encephalopathy via promoting mitophagy and repressing NLRP3 inflammasome activation Xiao-dan YanYu YangQing Yu Original Investigation 26 April 2025
Oxiracetam ameliorates neurological function after traumatic brain injury through competing endogenous RNA regulatory network Liyi WangHan GuoXuhua Cao Original Investigation 24 April 2025
Incremental efficacy systematic review and meta-analysis of psilocybin-for-depression RCTs Nicholas C. BorgognaTyler OwenBenjamin D. Hill Review Open access 23 April 2025
Embracing change: impermanence acceptance mediates differences in death processing between long-term ayahuasca users and non-users Jonathan DavidAviva Berkovich-OhanaYair Dor-Ziderman Original Investigation Open access 23 April 2025
The effect of nicotine on threat avoidance behaviour in healthy non-smokers Madeleine MuellerChristoph KornJan Haaker Original Investigation Open access 22 April 2025
Cognitive flexibility of male rats is increased by augmented punishment in a reversal learning task but ketamine has no detectable long-term effects Anthony N. NistStephen J. WalshTimothy A. Shahan Original Investigation 22 April 2025
A scoping review of the effects of serotonergic psychedelics on attitudes towards death Noah N. T. BarrKayla J. GieseSam G. Moreton Review Open access 21 April 2025
Distinct subcircuits within the mesolimbic dopamine system encode the salience and valence of social stimuli Erica A. CrossJohnathan M. BorlandH. Elliott Albers Original Investigation Open access 18 April 2025
Assessment of abuse potential of furanylfentanyl and tetrahydrofuranylfentanyl Yuanyuan ChenMiaojun LaiPeng Xu Original Investigation 17 April 2025
MiR-223-3p inhibits hippocampal neurons injury and exerts anti- anxiety/depression-like behaviors by directly targeting NLRP3 Wenyuan WangTingting YangYanyong Wang Original Investigation Open access 16 April 2025
Disruptive effects of d-amphetamine on conditioned sexual inhibition in the male rat Katuschia GerméDhillon PersadJames G. Pfaus Original Investigation 15 April 2025
Behavioural effects of oral cannabidiol (CBD) treatment in the superoxide dismutase 1 G93 A (SOD1G93 A) mouse model of amyotrophic lateral sclerosis Sandip GhimireFabian KreilausTim Karl Original Investigation Open access 14 April 2025
Modulation of strategic status signaling: oxytocin changes men’s fluctuations of status products preferences in their female partners’ menstrual cycle Honghong TangHongyu FuChao Liu Original Investigation 14 April 2025
The evolution of N, N-Dimethyltryptamine: from metabolic pathways to brain connectivity Swanti GuptaRaj K. BhatnagarAmla Chopra Review 11 April 2025
Quercetin ameliorates chronic restraint stress- and LPS-induced anxiety-like behaviors by modulating neuroinflammation in the lateral hypothalamus Xinxin WangGuangdong WengChengxin Zhang Original Investigation 10 April 2025
Comment on the study “the efficacy and safety of zuranolone for treatment of depression: a systematic review and meta-analysis” Mohammad UmerZaofasha ZaheerAiman Naveed Letter to the Editor 08 April 2025
