Buccal micronucleus cytome assay to evaluate cyto-genotoxic effects of occupational exposure to antineoplastic drugs: application on a large sample size of workers furnished by an Italian network of oncological hospitals C. L. UrsiniE. Omodeo-SalèD. Cavallo Genotoxicity and Carcinogenicity Open access 14 June 2025
Chronic arsenic exposure and hsa-miR-186 overexpression causes transcriptome-wide differential alternative splicing contributing to skin carcinogenesis in human HaCaT cell line Mayukh BanerjeeJared L. ScottJ. Christopher States Inorganic Compounds 13 June 2025
Transgenerational diabetogenic effects of preconception exposure to inorganic arsenic in C57BL/6 mice are associated with dysregulation of DNA methylation and gene expression in G1 and G2 offspring Bingzhen ShangTianyi LiuMiroslav Stýblo Inorganic Compounds 12 June 2025
Deriving safe limits for N-nitroso-bisoprolol by error-corrected next-generation sequencing (ecNGS) and benchmark dose (BMD) analysis, integrated with QM modeling and CYP-docking analysis Stephanie SimonJörg SchlingemannJessica Dieckhoff Regulatory Toxicology Open access 11 June 2025
Protective effects of flavonoids against silver nanoparticles-induced toxicity Inês SantosAdelaide SousaMarisa Freitas Review Article Open access 10 June 2025
Hepatic stellate cell inhibition by angiotensin II receptor blocker mitigates liver injury and fibrosis via NF-κB-galectin-3 suppression in a rat nonalcoholic steatohepatitis model Xiaochen KuangAya Naiki-ItoSatoru Takahashi Organ toxicity and mechanisms 09 June 2025
An evaluation of the human relevance of the hepatocellular tumors observed in mice treated with synthetic fungicide, pyridachlometyl, based on mode of action Kensuke KawamotoYukako ShimotsumaTomoya Yamada Genotoxicity and Carcinogenicity 09 June 2025
The emergence of nitazenes: a new chapter in the synthetic opioid crisis Cristian CaprariElena FerriGiuseppe Cannazza Review Article 09 June 2025
Enantioselective transplacental transfer of xenobiotics: mechanisms, plasma protein binding, and health implications for fetal development Xiaomeng YangKashif HayatWeiping Liu Toxicokinetics and Metabolism 07 June 2025
Daunorubicin and its hydroxy metabolite in cardiomyocytes: insights into cellular kinetics, toxicity, DNA damage, and dexrazoxane-induced cardioprotection Lenka ApplováPaulína Dudášová-HatokováTomáš Šimůnek Organ Toxicity and Mechanisms Open access 07 June 2025
Biocompatibility testing and antioxidant properties of cerium dioxide nanoparticles in human nervous system cells Natalia Fernández-BertólezAssia TouzaniVanessa Valdiglesias Inorganic Compounds Open access 06 June 2025
Genetic alterations in coronary cell lines exposed to sirolimus and paclitaxel Elaine Aparecida de CamargoGlenda Nicioli da SilvaDaisy Maria Fávero Salvadori Genotoxicity and Carcinogenicity 06 June 2025
Impact of physical activity on ethoxy- and propoxypropanol human toxicokinetics in vivo Hélène P. De LucaMyriam BorgattaNancy B. Hopf Analytical Toxicology Open access 05 June 2025
Environmental occurrence, human exposure routes, toxicity, and risk assessments of medium-chain chlorinated paraffins (MCCPs): a comprehensive review Zhi-Hong YuYing-Wen MuTao Zeng Review Article 05 June 2025
Comprehensive analysis of high-throughput transcriptomics to distinguish drug-induced liver injury (DILI) phenotypes Sangyeon ShinChanhee LeeTaesung Park In silico Open access 04 June 2025
A novel polypeptide from stony coral Goniopora columna inhibits thrombosis by interfering with the contact-kinin pathway Qian ChenCongshuang DengRen Lai Biologics 04 June 2025
The neurotoxic threat of micro- and nanoplastics: evidence from In Vitro and In Vivo models Ana Margarida AraújoCarolina MotaIsabel M. P. L. V. O. Ferreira Review Article Open access 03 June 2025
An update on the involvement of inflammatory mediators in Parkinson’s disease pathogenesis Oyashvi VermaMohd FaizanMahendra Pratap Singh Review Article 03 June 2025
Whether aristolochic acid directly drives hepatocarcinogenesis: comprehensive investigations from mutational signatures to animal models Lu YangWanjun LinWenzhe Ma Review Article 30 May 2025
Correction: Mitigation of depleted uranium-induced mitochondrial damage by ethylmalonic encephalopathy 1 protein via modulation of hydrogen sulfide and glutathione pathways Juan LiYong LiYuhui Hao Correction 29 May 2025
Neurodevelopmental toxicity and mechanism of chlorinated polyfluoroalkyl ether sulfonate alternative F-53B in pubertal male rats Lu SunYao ChenXiangyang Wu Reproductive Toxicology 28 May 2025
Toxicological concerns regarding glyphosate, its formulations, and co-formulants as environmental pollutants: a review of published studies from 2010 to 2025 Szandra KlátyikGergely SimonAndrás Székács Review Article Open access 26 May 2025
A framework for evaluating less-than-lifetime exposures: advancing toxicological risk assessment for drinking water quality Sanah MajidAstrid ReusMilou M. L. Dingemans Review Article Open access 25 May 2025
Framework for classifying chemicals for repeat dose toxicity using NAMs J. E. DoeP. BothamS. J. Wijeyesakere Regulatory Toxicology Open access 24 May 2025
Tail-less precursors in synthetic cannabinoid production: investigating a clandestine laboratory, seized samples, and CB1 activity Manuela Carla MontiTobias RautioCaitlyn Norman Inorganic Compounds Open access 23 May 2025
In vitro toxicological assessment using NCI-H292 cells of the relationship between cytotoxic effects and chemical composition in flavored e-liquids Shuhong ZhangYumeng ZhangHongwei Hou In vitro systems 22 May 2025
Validation of new AI-based classification method for in silico cardiac safety assessment of drugs following the CiPA framework Ulfa Latifa HanumAli Ikhsanul QauliKi Moo Lim Organ Toxicity and Mechanisms 22 May 2025
Molecular dosimetry of estragole and 1′-hydroxyestragole-induced DNA adduct formation, clastogenicity and cytotoxicity in human liver cell models G. AckermannM. PeilJ. Fahrer Organ Toxicity and Mechanisms Open access 21 May 2025
Temporal analyses of germ cell mutations using the MutaMouse model support the recommended design in OECD test guideline 488 Gu ZhouAndrew WilliamsFrancesco Marchetti Regulatory Toxicology Open access 21 May 2025
Bridging approaches to facilitate innovation: building an approach for heated tobacco products from case studies in the food and drug domains a comparative review Ruth DempseyIrfan GunduzPatrick Vanscheeuwijck Review Article Open access 21 May 2025
Human metabolism and excretion kinetics of Bronopol after oral administration Isabell SchönrathChristoph SchmidtkunzGabriele Leng Toxicokinetics and Metabolism 20 May 2025
Structure–metabolism relationships of 4-pentenyl synthetic cannabinoid receptor agonists using in vitro human hepatocyte incubations and high-resolution mass spectrometry Steven R. BaginskiKarin LindbomHenrik Gréen In vitro systems Open access 20 May 2025
In vitro CB1 receptor activity of halogenated indazole synthetic cannabinoid receptor agonists Henrik GreenCraig McKenzieCaitlyn Norman In vitro systems Open access 18 May 2025
Metabolic activation and cytotoxicity of carvedilol mediated by cytochrome P450s in vitro and in vivo Shibo SunYang WangJiang Zheng Toxicokinetics and Metabolism 17 May 2025
Discovering a predictive metabolic signature of drug-induced structural cardiotoxicity in cardiac microtissues Tara J. BowenAndrew R. HallMark R. Viant Organ Toxicity and Mechanisms Open access 16 May 2025
How to organise a successful toxicology workshop? A participant perspective on the Collaboration to Harmonise the Assessment of Next Generation Evidence (CHANGE) workshop in Oslo, 18–20 June 2024 Michael G. DiemarArianna GiustiAnne Kienhuis Meeting Report Open access 15 May 2025
TRPM7 underlies cadmium cytotoxicity in pulmonary cells Leonor CorreiaAlexey ShalyginVladimir Chubanov Inorganic Compounds Open access 15 May 2025
Exposure risk assessment of di(2-ethylhexyl)phthalate (DEHP) using human population pharmacokinetic modeling of DEHP and its major in vivo metabolites Ji-Hun JangSeung-Hyun Jeong Toxicokinetics and Metabolism 15 May 2025
Letter to the editor regarding “Bichlmaier, I. Differences in endocrine and reproductive responses to substance exposure across generations: highlighting the importance of complementary findings. Arch Toxicol 98, 3215–3230 (2024)” J. H. E. ArtsL. F. TempestE. Van Miert Letter to the Editor, News and Views 14 May 2025
The alarming consequences of workforce reductions at the FDA, EPA, NIH and CDC in the United States Daniel R. DietrichSonja von AulockMartin van den Berg Editorial Open access 13 May 2025
Identifying metabolites of new psychoactive substances using in silico prediction tools Romain PelletierDina NahleThomas Gicquel In silico Open access 13 May 2025
Green tea catechins: protectors or threats to DNA? A review of their antigenotoxic and genotoxic effects María del Carmen García-RodríguezSam Kacew Review Article Open access 13 May 2025
Advancing in vitro assessment of iodide uptake inhibition: integrating a novel biotransformation pretreatment step Puja KumariSebastian Lungu-MiteaKlára Hilscherová Inorganic Compounds Open access 12 May 2025
A proposal of criteria to support the EU classification on endocrine disruption for the thyroid modality and their application to four data-rich case studies Stephanie Melching-KollmussUrsula G. SauerHelen Tinwell Regulatory Toxicology Open access 10 May 2025
Delayed complications of sulfur mustard poisoning: a focus on inflammation and telomere footprint Alireza NourazarianSeyed Mohsen Aghaei-ZarchYasin Panahi Review Article 07 May 2025
A tiered next-generation risk assessment framework integrating toxicokinetics and NAM-based toxicodynamics: “proof of concept” case study using pyrethroids Ana Fernandez-AgudoJose V. Tarazona Regulatory Toxicology Open access 07 May 2025
Improving how we use workshops when solving complex research problems: reflections from the CHANGE project Lowenna B. JonesPaul WhaleyGro H. Mathisen Meeting Report Open access 06 May 2025
A clinical chemical atlas of xenobiotic toxicity for the Sprague–Dawley rat Janonna KadyrovSamuele SalaJulien Wist Short Communication Open access 06 May 2025
Human sperm as an in vitro toxicity model: a versatile tool for assessing the risk of environmental contaminants Shannen KeyserDaniel MarcuLiana Maree In vitro systems Open access 03 May 2025
