Sigma-1 Receptor Activation Alleviates iBRB Dysfunction after I/R Injury by Inhibiting Endoplasmic Reticulum Stress-Dependent Autophagy Jian YuJiaojiao WeiChunhui Jiang Research 01 June 2025
The Role of Gut-Brain Tryptophan Metabolism and Fatty Acid Peroxidation in the Effect of Sleep Deprivation on Anxiety and Depression in PCOS Mice Ting HanShangjing LiuTing-Li Han Research 31 May 2025
Alexander’s Disease: Potential Drug Targets and Future Directions Emily ZavalaTahl Zimmerman Review Open access 31 May 2025
Application of microRNA In Situ Hybridization on Long-term Stored Human Formalin-fixed Paraffin-embedded Brain Samples from Psychiatric Patients Rolf SøkildeErik KaadtBetina Elfving Research Open access 31 May 2025
Accurate Quantification of Mutant and Wild-Type polyQ Proteins Using Simple Western Capillary Immunoassays Bas RöttgeringJanwillem TesterinkNicole Datson Research Open access 31 May 2025
Chronic Exercise Protects Against Cognitive Deficits in an Alzheimer’s Disease Model by Enhancing Autophagy and Reducing Mitochondrial Abnormalities Gustavo Paroschi MoraisIvo Vieira de Sousa NetoAdelino Sanchez Ramos da Silva Research 31 May 2025
Neuroprotective Effects of Hesperidin and CK2 Inhibitor DRB on Aβ1-42-Induced Neurotoxicity in Differentiated SH-SY5Y Cells Hamiyet Eciroglu-SarbanPinar Altin-CelikHamiyet Donmez-Altuntas Research Open access 30 May 2025
Whole-Brain Monosynaptic Inputs to Parasubthalamic Calretinin Neurons in Mice Han GuoMutian ZhangZhili Huang Research 30 May 2025
Inhibition of Cathepsin B Ameliorates Murine Cognitive Dysfunction and Neuronal Damage in Ischemic Stroke by Inhibiting Mitochondrial Apoptosis and Drp1-Mediated Mitochondrial Fission Hongyi JiaBingge ZhangQinghua Hou Research 30 May 2025
Combination Therapy of Estrogen and Progesterone Attenuates Behavioral Impairments and Autophagy via circLrp1b/miR-27a-3p/Dram2 Pathway After Traumatic Brain Injury Ladan AmirkhosraviMohammad KhaksariSarieh shahraki Research 29 May 2025
Melatonin Supplementation in Alzheimer’s disease: The Potential Role in Neurogenesis Rasoul EbrahimiAli FaramarziKhadijeh Esmaeilpour Review 29 May 2025
Dermorphin [D-Arg2, Lys4] (1–4) Amide Attenuates Burn Pain by Inhibiting TRPV1/NR2B Mediated Neuroinflammatory Signalling Ajay ModiAnkit UniyalVinod Tiwari Research 29 May 2025
Identification of NLRP3 Inflammasome-associated Biomarkers by Integrated Bioinformatics Analysis in Neuropathic Pain Dongdong LiuShaopeng HuangJinfeng Liu Research 29 May 2025
Late-Stage Activation of Toll-like receptor 3 Alleviates Cognitive Impairment and Neuropathology in an Alzheimer’s Disease Mouse Model Taiyang ZhuFanyu ShenFang Hua Research Open access 28 May 2025
Spirilloxanthin from Verbesina encelioides Flower Extract has Neuroprotective Benefits in Scopolamine-Induced Memory Impaired Rats that Resemble Alzheimer’s Disease Vartika VermaLavisha RaoNidhi Srivastava Research 28 May 2025
Correction: Emodin, a Potent Anthraquinone Mitigates MPTP-Induced Parkinsons’ Disease Pathology by Regulating Nrf2 and Its Downstream Targets: In Silico and In Vivo Approach Sarwat JahanMuhammad IkramNasir Ahmad Correction 27 May 2025
Elucidating the Antidepressant-Like Effect of Tannic Acid in Mice: Modulation of Serotonergic System and Pro-Inflammatory Mediators Karina Pereira LuduvicoJulia Eisenhardt de MelloFrancieli Moro Stefanello Research 27 May 2025
Trifluoperazine improves postoperative cognition by influencing astrocyte endfoot morphology and aquaporin-4 polarity Chunqu ChenBinbin ZhuJianhua Wang Research 27 May 2025
LncRNA SNHG14 Regulates the Expression of BDNF by Recruiting Histone Methyltransferase EZH2 to Mediate H3K27me3, Thereby Affecting Angiogenesis and Functional Recovery After Cerebral Ischemia Tao DingLi Zhang Research 26 May 2025
SOD1, A Crucial Protein for Neural Biochemistry: Dysfunction and Risk of Amyotrophic Lateral Sclerosis José Raphael Monteiro NetoGabriel Freitas de SouzaElis Cristina Araujo Eleutherio Review 26 May 2025
SFRS8 Regulates Memory by Modulating RNA Splicing of Synaptic Genes Zeng DingQiang LiuJuan Zhang Research 26 May 2025
Calcium Signaling in Astrocytes and Its Role in the Central Nervous System Injury Xinyue LiLu DingDavid Y. B. Deng Review 26 May 2025
Nociceptin/OrphaninFQ Receptor Modulates the Maturation of Adult-Born Neurons in the Mouse Dentate Gyrus Under Physiological Conditions and in a Chronic Stress Model Cathaline RobertFlora D’Oliveira da SilvaLionel Moulédous Research Open access 26 May 2025
PDZD8 Dysregulation Mediates RVLM Neuronal Hyperexcitation Via Activation of Ca2+-Calpain-2 Signaling in Stress-Induced Hypertension Tianfeng LiuLinping WangDongshu Du Research 26 May 2025
Peripheral Choroid/RPE/Sclera as a Shared Pathogenic Hub: Multi-Tissue Transcriptomic Profiling Identifies Common Differentially Expressed Genes in Age-Related Macular Degeneration and Alzheimer’s Disease Manjuan PengQi ZengXiaobo Xia Research 24 May 2025
Protein Structure-based FUS Mutational Subtypes Are Associated With Protein Mislocalization in Amyotrophic Lateral Sclerosis Patients Wanli YangZhen LuoMing Zhang Research 24 May 2025
Circulating Neuronal Exosome Cargo as Biomarkers of Neuroplasticity in Cushing’s Syndrome Marica PagliariniLoretta GuidiPatrizia Ambrogini Research Open access 24 May 2025
Leveraging Alzheimer’s Disease Omics to Identify Pleiotropic Genes Contributing to Neurodegeneration in Primary Open-Angle Glaucoma Paulina Tolosa-TortAndrew T. DeWan Research 24 May 2025
Inhibition of PolyGA Dipeptide Repeat Protein Aggregation by Nucleic Acid Aptamers in C9 Amyotrophic Lateral Sclerosis-Frontotemporal Dementia Models Swati JainDebanjana DasIpsita Roy Original Article 24 May 2025
The Impact of Maternal Obesity and Deprivation On Energy Metabolism, Oxidative Stress and Brain Antioxidant Defense in the Neurodevelopment of Offspring in the Short, Medium and Long Term Mariella Reinol SteinerAline Haas de MelloGislaine Tezza Rezin Research 24 May 2025
The Intricate Relationship of Trk Receptors in Brain Diseases and Disorders Sarthak DahiyaPoonam SharmaNitin Sharma Review 23 May 2025
Investigating the Role of Neutrophil Extracellular Traps as a Therapeutic Target in Traumatic Brain Injury: a Systematic Review and Meta-analysis Elliott SloughAnna Pitt-FrancisAndrew R. Stevens Review Open access 23 May 2025
Aberrant Expression of TH2LCRR and GATA3 in Peripheral Blood Mononuclear Cells of Patients with Acute-Phase Schizophrenia: Integrative Bioinformatics Analysis and Experimental Study Elahe MoghisehAli MassoudifarMasoumeh Mahmoodi Research 23 May 2025
GPX4 Inhibition Contributes to NLRP3-Mediated Pyroptosis and Cognitive Impairment in Ketamine-Exposed Neonatal Rats Hui BaiShan DuZhiheng Zhang Research 23 May 2025
Human Neural Progenitor Cell-Derived Exosomes Deliver miR- 100 - 5p Targeting NOX4 mRNA to Alleviate Oxidative Stress in Acute Ischemia Injury Xianlei ZhaoChenjie GuJianwei Pan Research Open access 22 May 2025
The Role of Fatty Acid Binding Protein 7 in Neurological Diseases Yingxi ChenJiarui LiuWeihua Yu Review 22 May 2025
Microglial Responses to MSC-EVs Treatment in Animal and Cellular Models of Ischemic Stroke: a Systematic Review with Meta-analysis Luis Pedro BernardiThomas Hugentobler SchlickmannDiogo Onofre Souza Review 22 May 2025
Deletion of ZNRF2 Exacerbates MPTP-Induced Parkinson’s Disease by Activating mTOR-Mediated Neuroinflammatory Pathways Fanshi ZhangJingqing XuMei Liu Research 22 May 2025
Glycation in Alzheimer’s Disease and Type 2 Diabetes: The Prospect of Dual Drug Approaches for Therapeutic Interventions Sama AyoubMaryam ArabiAli Chaari Review Open access 22 May 2025
Intervention Role of APOE in CNS Diseases: APOE Actions and APOE Neurogenesis Capability Wenhua LiSuya MaMin Li Review 22 May 2025
The Role of HbA1c in Parkinson's Disease: An Integrative Analysis by Single-Cell, Bulk Transcriptome and Mendelian Randomization Huihe ZhangWei LiYue Jiang Research 21 May 2025
Resveratrol Alleviates Diabetic Adipose Tissue–Derived Extracellular Vesicles–Induced Hippocampal Ferroptosis and Cognitive Dysfunction via Inhibiting miR-9-3p/SLC7A11 Axis Ying HuJixiong XuQin Zhang Research 20 May 2025
Hippocampal Interneurons Shape Spatial Coding Alterations in Neurological Disorders Juliane Midori IkebaraRenata Silva JorgeAlexandre Hiroaki Kihara Review 20 May 2025
S100B Mitigates Cytoskeletal and Mitochondrial Alterations in a Glial Cell Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay Ana Sofia BoasinhaFernanda MurtinheiraFederico Herrera Brief Report Open access 19 May 2025
Ion Channels and G-Protein-Coupled Receptors Involved in the Development of Chronic Post-ischemic Pain (CPIP): A Model of Complex Regional Pain Syndrome (CRPS-I) Náthaly Andrighetto RuviaroPatrícia RodriguesGabriela Trevisan Reviews 19 May 2025
Serum sEV miRNAs as Biomarkers in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease Hark Kyun KimHyunjin JuJu-Hong Min Research Open access 19 May 2025
Analgesic Effects of Acupressure on Jing-jiaji Acupoints in a Rat Model of Cervical Spondylotic Radiculopathy Shang-Hong JiangSong YangXue-Yu Jiang Research 17 May 2025
High-Fat Diet-Induced Excessive Accumulation of Cerebral Cholesterol Esters and Microglial Dysfunction Exacerbate Alzheimer's Disease Pathology in APPNL−G−F mice Shuhan YangHirofumi MiyazakiYuji Owada Research Open access 17 May 2025
Cold-Induced RNA-Binding Protein (CIRP) Affects Cerebral Ischemia–Reperfusion Injury Through NF-κB Pathway Yong FanJingjing WeiYongkai Yang Research 17 May 2025
The Selective Glucocorticoid Receptor Modulator Cort125329 Decreases Neuroinflammation and Gliosis and Enhances Myelination in the Wobbler Model of Amyotrophic Lateral Sclerosis Iván EsperanteCarolina BanzanMaría Meyer Research 17 May 2025
