Evaluation of Therapeutic Potential of a Selective 5α-reductase Inhibitor against Glioblastoma: Molecular Docking and In Vitro Insights Anil SharmaSatvika SharmaVijayta D. Chadha Original Paper 18 June 2025
Molecular Mechanisms Behind Organ-Related Aging and Regulatory Effects of Natural Therapeutics Rimsha AbaidullahShaukat AliHunaiza Tahir Review Paper 17 June 2025
A Cross-sectional In Vitro Study on the Synergistic Neuroprotective Effects of Phytochemicals Ferulic Acid and Ginkgolide B against Amyloid Beta-induced Oxidative Stress and Modulation of Multifunctional Enzyme APE1/Ref-1 in Human Neuroblastoma SH-SY5Y Cells Harkomal VermaAnuradha YadavAnil Kumar Mantha Original Paper 16 June 2025
Network Pharmacology and Experimental Evidence Identify the Mechanism of Astragaloside IV against Henoch-Schönlein Purpura Nephritis Shuang PangQinghao YanLiping Yue Original Paper 16 June 2025
Molecular Docking, Phytochemical Screening and Evaluation of Balliospermum montanum Roots for its Antihyperlipidemic Potential Shahzadi BanoJamal Akhtar AnsariAbdul Rahman Khan Original Paper 13 June 2025
A Computational and In Vitro Appraisal of Ostarine to Target Androgen Receptor in Glioma C6 Cells Satvika SharmaSandeep SainiDevinder Kumar Dhawan Original Paper 13 June 2025
A Risk Prognostic Signature Basing on Cuproptosis-related Ferroptosis and Immune Genes for Esophageal Squamous Cell Carcinoma Patients Jie MaDan LiuFeng Zhu Original Paper 12 June 2025
Cytotoxic, Genotoxic, Apoptotic, and Reactive Oxygen Generating Properties of Bioactive Quinoline Derivatives as Novel Anti Breast Cancer Agents Vildan Betul YenigunEray Metin GulerOsman Çakmak Original Paper 10 June 2025
Bladder Cancer Growth is Inhibited by Upregulating CircFUT8 through the METTL14/FMR1 Signaling Pathway Weifeng YangJinhui ZhaShiheng He Original Paper 10 June 2025
Rational Design of Chlorinated Hydroxyxanthone as Anticancer Agent: Molecular Docking, Molecular Dynamic Simulation, ADMET, One-Pot Synthesis, and In Vitro Evaluation Yehezkiel Steven KurniawanHarizalEti Nurwening Sholikhah Original Paper 09 June 2025
Correction: NanoBiT-based Analysis of Canine SOD1 Protein Dynamics: Understanding the Role of CCS and Ebselen Derivatives as Potential Therapeutics for Canine Degenerative Myelopathy Sakura HiroseYui KobatakeKentaro Oh-hashi Correction 06 June 2025
A Catalytic Charioteer: An Ode to Sampath Parthasarathy, PhD, MBA, FAHA Sanjay Rajagopalan Letter to the editor Open access 04 June 2025
Antioxidative Effects of Crocin-loaded Noisome in Paraquat-induced Oxidative Stress in Lung Rat Anahita AbbasifardAshkan KarbasiAkram Ranjbar Original Paper 04 June 2025
Integrative Network Pharmacology, Molecular Docking, and Dynamics Simulation Guided Discovery of Anethole, Carvacrol, Carnosol, Nicotine, and Paeonol as Potential Therapeutics for Parkinson’s Disease Md. Touki Tahamid TusarMd. Masudur Rahman MunnaMd. Sarafat Ali Original Paper 04 June 2025
Lysine Demethylase 5B Alleviates Neuroinflammation in Ischemic Stroke by Repressing Steap4 Qi YinHua ShaoFengjun Wang Original Paper 31 May 2025
FOXA1 Transcriptional Repression of PLSCR1 Inhibits Tongue Squamous Cell Carcinoma Progression Jinxin WangCong ZhangChunbin Duan Original Paper 30 May 2025
The Mediating Role of Plasma Inflammatory Proteins in Gut Microbiota-Driven Valvular Heart Disease: A Mendelian Randomization Study Jiajing ZhaoYuhan WangLijuan Shen Original Paper 28 May 2025
Mechanistic Insights into Polyphenols-mediated Squalene Epoxidase Inhibition: Computational Models and Experimental Validation for Targeting Cholesterol Biosynthesis Emadeldin M. KamelAhmed A. AllamAl Mokhtar Lamsabhi Original Paper 26 May 2025
WTAP-induced m6A Methylation of Atoh8 Promotes Cell Proliferation and Fibrosis in Diabetic Nephropathy Suyu WangHenglu ZhangMei Zhang Original Paper 22 May 2025
Influence of Ubiquitin Mutations over Molecular Markers Contributing to Pathogenesis of Candida albicans Sandeep Kumar DantusliaAnkita DoshiC. Ratna Prabha Original Paper 21 May 2025
A Machine Learning Method for Predicting Acute Kidney Injury in Patients with Intracranial Hemorrhage Bo LiuDi WuHua Liu Original Paper 21 May 2025
Investigate the Effect of ZFP64 on mRNA Expression of HBG Based on Bioinformatics and Experimental Validation Siqi HuangJianfeng WuYingjun Xie Original Paper 20 May 2025
Native Fluorescence Characterization of Blood Plasma for Early Diagnosis of Oral Potentially Malignant Disorders Pravda ChidambaranathanRajvikram NatarajanAruna Prakasarao Original Paper 19 May 2025
Syringic Acid in Canarium odontophyllum for Diabetes and Obesity – A Review Gilbert RinggitBo Eng CheongShafiquzzaman Siddiquee Review Paper 16 May 2025
A Potent Plant-Derived Chitinase: Structural Informatics and Insecticidal Activity against Helicoverpa armigera Shah RukhAhmed AkremMohibullah Shah Original Paper 15 May 2025
Correction: Icariside II Alleviates Chondrocyte Inflammatory Injury by Inhibiting the TNIP2/NF-κB Pathway Jiajun MeiHongkui KeJunsong Zhu Correction 14 May 2025
Effects of Turmeric on Manganese-induced Redox Imbalance in Testicular Tissues: Histo-micrometric and Biochemical analyses Fatima Bashir AhmadChaman AraAsmatullah Original Paper 14 May 2025
Micronized Purified Flavonoid Fraction (Diosmin/Hesperidin) Ameliorates Cardiac Structural and Functional Integrity in Cisplatin-treated Male Wistar Rats by Modulating NLRP3/Caspase-1/-3 Signaling W. A. SakaP. A. OyedokunR. E. Akhigbe Original Paper 13 May 2025
Palmitic Acid-induced Renal Injury: Unravelling the Molecular Mechanisms and the Protective Role of Lycopene Adewale S. JamesEmmanuel I. UgworRegina N. Ugbaja Letter to the editor 13 May 2025
The Paeonol of Total Glucosides of White Peony Regulates the Differentiation of CD4+Treg Cells through the EP300/Foxp3 Axis to Relieve Pulmonary Fibrosis in Mice Muyun YanQing WangHuamei Chen Original Paper 12 May 2025
NanoBiT-based Analysis of Canine SOD1 Protein Dynamics: Understanding the Role of CCS and Ebselen Derivatives as Potential Therapeutics for Canine Degenerative Myelopathy Sakura HiroseYui KobatakeKentaro Oh-hashi Original Paper 12 May 2025
Glycyrrhiza pallidiflora Polysaccharide Ameliorates DSS-Induced Colitis by Protecting Intestinal Barrier Integrity Dandan ZengWeijie RenTianlu Mo Original Paper 09 May 2025
Elucidating the Phytochemical, Antibacterial, and Hepatoprotective Effects of Elaeagnus umbellata Leaf Extract Against Liver Injury in an Animal Model Nausheen NazirSajid KhanMaher S. Alwethaynani Original Paper 01 May 2025
Computational Drug Repurposing Screening Targeting Profibrotic Cytokine in Acute Respiratory Distress Syndrome Yong MaoWei XuHandi Liao Original Paper 30 April 2025
Development of Novel α-Amylase Inhibitors: Synthesis, Molecular Docking, and Biochemical Studies K. RamakrishnanReshma RajanRajagopal Desikan Original Paper 29 April 2025
Correction: Cinnamaldehyde Alleviates Alveolar Epithelial Cell Injury in ALI by Inhibiting the CaMKII Pathway Lei LiuHao ZhangZhou Zheng Correction 28 April 2025
Synergistic Enhancement of Apo2L/TRAIL and DR4-Induced Apoptosis by Arsenic Trioxide in Triple-Negative Breast Cancer Cells: A Comparison to Conventional Chemotherapy Soraya MoomivandMohsen NikbakhtSeyed Asadoullah Mousavi Original Paper 28 April 2025
Macrophage Polarization-Based Analysis of the Role of the FOXM1/KIF20A Axis in Breast Cancer Metastasis Yuanbin WangRuimin MaZhihao Wu Original Paper 28 April 2025
ABT263 Ameliorates Cellular Senescence, Aβ-Dependent Pathology and Cognitive Decline in Aged APP/PS1 Mice via Regulating PI3K/AKT/GSK-3β Pathways Zhi TangXiao-Ling WangXiao-Lan Qi Original Paper 28 April 2025
A Computational Approach for Designing a Peptide-Based Acetyl-CoA Synthetase 2 Inhibitor: A New Horizon for Anticancer Development Musab AliErnest Oduro-KwatengMahmoud E. S. Soliman Original Paper Open access 27 April 2025
Molecular Mechanism of Notch Signaling and Macrophages in Deep Vein Thrombosis: A Comprehensive Review Sisira JoyAnusha PrasannanAmbika Binesh Review Paper 25 April 2025
Correction: Chaperone-Mediated Autophagy Reactivation Protects Against Severe Acute Pancreatitis-Associated Liver Injury Through Upregulating Keap1/Nrf2 Signaling Pathway and Inhibiting NLRP3 Inflammasome Activation Zhongbiao LiYue YuDianliang Zhang Correction 22 April 2025
Structural and Energetic Insights into the Binding of L- and D-Arginine Analogs with Neuropilin-1 (NRP1): Molecular Docking, Molecular Dynamics and DFT Calculations Mahmoud A. A. IbrahimDina E. M. MohamedPaul W. Paré Original Paper 20 April 2025
Structural Mechanisms Driving the Selective Efficacy of Oxamniquine against Schistosoma mansoni and Schistosoma japonicum Kehinde F. Paul-OdeniranEmmanuel A. IwuchukwuPaul O. Odeniran Original Paper Open access 19 April 2025
Correction: In vitro Chondrogenic Induction Promotes the Expression Level of IL-10 via the TGF-β/SMAD and Canonical Wnt/β-catenin Signaling Pathways in Exosomes Secreted by Human Adipose Tissue-derived Mesenchymal Stem Cells Tugba Semerci SevimliUlukan InanAhmet Emin Topal Correction 18 April 2025
Identification of circRNA-Based Biomarkers and ceRNA Mechanism in Non-Small Cell Lung Cancer Zhengjia LiuXiyu LiuHaixiang Yu Original Paper 18 April 2025
PM2.5 Induced Vascular and Myocardial Calcification Impairs Ischemia-reperfusion Tolerance via Mitochondrial Dysregulation Bhavana SivakumarGino A. Kurian Original Paper 18 April 2025
The Regulatory Role of NcRNAs in Pyroptosis and Disease Pathogenesis Shaocong WangXinzhe ChenSumin Yang Review Paper 18 April 2025
Difference Analysis of MiRNA Expression Profiles in Aged Female Rat Adipose Tissue Regulated by HIIT and MICT Pinshi NiYingmin SuFanghui Li Original Paper 18 April 2025
Investigating Network and Experimental Effect of Silibinin on Lipin-1 and Lipin-2 Gene Expression during Ischemia-reperfusion of the Liver in Rats Mahboubeh GhanbariHossein EbrahimiHadis Mousavi Original Paper 17 April 2025
