As the primary producers of adenosine triphosphate (ATP) mitochondria are central in the maintenance of cellular bioenergetic state. Moreover, these organelles provide an important source of reactive species...
Lysosomal storage diseases (LSD) are a group of inherited metabolic disorders caused by mutations of genes encoding lysosomal proteins involved in degradation of macromolecules. Thus, incompletely degraded m...
Due to the population growth and healthcare advancements that have extended human longevity, early diagnosis of debilitating neurodegenerative disorders such as Parkinson’s disease (PD), Alzheimer's disease ...
It has been established that the common neurodegenerative diseases such as Alzheimer disease (AD), Parkinson disease (PD), Huntington diseases (HD), amyotrophic lateral sclerosis (ALS) and other motor neuron...