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SENP3 alleviates osteoporosis via promoting SIRT3 transcription through the increase of DLX2 stability via SUMO2/3 Jie BuXuezheng XuFeng Zhou RESEARCH Open access 10 June 2025 Article: 99
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Loss of YTHDF1 suppresses the progression of malignant rhabdoid tumor of the kidney by regulating Glutathione S-transferase Mu 2 (GSTM2) Qian-Wen XiongYuntao LiuWan-Xin Peng RESEARCH Open access 07 June 2025 Article: 96
Exosomal POU5 F1 derived from TNBC promotes cancer progression by regulating M2 macrophage polarization via inhibiting TRAF6 ubiquitination and activating AKT in macrophage Yimeng ChaiYao Shi RESEARCH Open access 03 June 2025 Article: 95
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Integrated machine learning survival framework develops a prognostic model based on macrophage-related genes and programmed cell death signatures in a multi-sample Kidney renal clear cell carcinoma Xuefei LiuMin DengLimin Yang RESEARCH Open access 30 May 2025 Article: 93
cIAP2-mediated IGF2BP2 ubiquitination and degradation regulate cardiomyocyte apoptosis via stabilizing m6A-modified BAX mRNA in myocardial infarction Cong WangJijia LiuHaidan Liu RESEARCH Open access 30 May 2025 Article: 92
The key regulator circPDE3B promotes arsenic-induced bladder carcinogenesis by affecting STAT3 and NF-κB stability Yihong GaoHaotian XuAruo Nan RESEARCH Open access 28 May 2025 Article: 91
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IFI204 in microglia mediates traumatic brain injury-induced mitochondrial dysfunction and pyroptosis via SENP7 interaction Ting GuoYongxing LaiFan Lin RESEARCH Open access 23 May 2025 Article: 89
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Neuron-like macrophage differentiation via the APOE-TREM2 axis contributes to chronic pain in nasopharyngeal carcinoma Hongxi LiLanqing ZhaoYu Chen RESEARCH Open access 20 May 2025 Article: 86
IGFBP3 enhances adipose-derived stem cell function in soft tissue injury repair via ITGB1 and ERK pathway activation Sirui TianHaiyang YuDanning Wang RESEARCH Open access 15 May 2025 Article: 85
U2AF65 mediated circPVT1 promotes NSCLC cell proliferation and inhibits ferroptosis through the miR-338-3p/GPX4 axis Lujuan HeZezhi ZhouShenggang Liu RESEARCH Open access 14 May 2025 Article: 84
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ELF4 improves sepsis-induced myocardial injury by regulating STING signaling-mediated T cells differentiation Yawen ZhengXiongjun PengJunke Long RESEARCH Open access 07 May 2025 Article: 82
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Rap2a promotes cardiac fibrosis and exacerbates myocardial infarction through the TNIK/Merlin/YAP axis Zhibin LangXiaozhen FanHongqi Lin RESEARCH Open access 07 May 2025 Article: 80
Mitigating chemotherapy-induced granulosa cell damage: role of hUCMSC-EVs in regulating the lncRNA HCP5-miR-20a-5p-YAP1 network Ying XieXiaoqin ChenDan Liu RESEARCH Open access 02 May 2025 Article: 79
Lactate-induced macrophage HMGB1 lactylation promotes neutrophil extracellular trap formation in sepsis-associated acute kidney injury Siwei WeiZijuan DaiZhen Du RESEARCH Open access 30 April 2025 Article: 78
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SDH defective cancers: molecular mechanisms and treatment strategies Jiaer WangTao YuanHong Zhu REVIEW Open access 26 April 2025 Article: 74
Ubiquitin-specific peptidase 10 attenuates bleomycin-induced pulmonary fibrosis via modulating autophagy depending on sirtuin 6-mediated AKT/mTOR Shitao MaoNa YuJian Kang RESEARCH Open access 25 April 2025 Article: 73
Machine learning-based identification of cuproptosis-related lncRNA biomarkers in diffuse large B-cell lymphoma Wenhao OuyangZijia LaiLi Ling RESEARCH Open access 21 April 2025 Article: 72
Npc1 gene mutation impairs multilineage differentiation potential of hepatic telocytes in murine models Jichao YangYuqiao ChangJuntang Lin RESEARCH Open access 21 April 2025 Article: 71
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Based exploration of the diagnostic value of oxidative stress-related key genes in chronic obstructive pulmonary disease Shenglan WangMingFeng ZhongMingMei Zhong RESEARCH Open access 11 April 2025 Article: 69
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Lamin A/C regulates cerebellar granule cell maturation Laura VilardoIngrid CifolaIgea D’Agnano RESEARCH Open access 05 April 2025 Article: 66
