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Establishment of a rapid RAA-CRISPR/Cas12a system targeting the recN gene for on-site detection of Streptococcus suis in livestock and fresh pork meat Jian YangWenjing LiHongning Wang Research 06 May 2025 Article: 99
Genomic dissection of terminal heat tolerance in synthetic hexaploid derived nested introgression libraries of wheat (Triticum aestivum L.) Amandeep KaurGuriqbal Singh DhillonSatinder Kaur Research 05 May 2025 Article: 98
Integration of metabolite and transcriptome profiles of cultivated and wild rice to unveil gene regulatory networks and key genes determining rice source and sink strength Anuradha SinghJyotirmaya MathanAashish Ranjan Research 01 May 2025 Article: 97
Mitochondrial genome evolution in the orchid subfamily Cypripedioideae (Orchidaceae) Shiyu QinHanchen WangXiaohua Jin Research 30 April 2025 Article: 96
RNA-binding protein HuR interacts with UFM1 mRNA to ameliorate chondrocyte inflammation, apoptosis and extracellular matrix degradation LeXiang LiRong ZhouJun Zhu Research 28 April 2025 Article: 95
Multi-omics integration reveals YWHAE as a key mediator of ferroptosis in ARDS Honghui CuiXia Huang Research 22 April 2025 Article: 94
SNP’s use as a potential chemotoxicity stratification tool in breast cancer: from bench to clinic Hebatallah Ahmed Mohamed MoustafaWalaa A. El-DakrouryAhmed S. Doghish Review 22 April 2025 Article: 93
Identification of a NEK7-related pyroptosis gene signature against pancreatic cancer and evaluation of its potential in tumor microenvironment remodeling via regulating inflammasome complex Jia LiuZilong YanXueqing Liu Research Open access 21 April 2025 Article: 92
A Multi-omics approach to identify and validate shared genetic architecture in rheumatoid arthritis, multiple sclerosis, and type 1 diabetes: integrating GWAS, GEO, MSigDB, and scRNA-seq data Tailin WangQian HeKei Hang Katie Chan Research Open access 21 April 2025 Article: 91
Identification and mechanistic analysis of shared biomarkers and pathogenesis in acute pancreatitis and sepsis based on differential gene expression and protein interaction networks Weina LuYifeng MaoJian Lan Research Open access 17 April 2025 Article: 90
Multi-omic profiling identifies KRT1 as a predictor of immune infiltration and prognosis in gastroesophageal junction cancer Tongkun SongJiangbo ChenXiangqian Su Research 15 April 2025 Article: 89
Exploring the molecular pathways of miRNAs in testicular cancer: from diagnosis to therapeutic innovations Yasser M. MoustafaSherif S. Abdel MageedAhmed S. Doghish Review 14 April 2025 Article: 88
EXO1 as a potential biomarker for prognosis, immune infiltration, and immunotherapy in pan-cancer analysis Jikang WangFubo WangHaoxuan Huang Research 11 April 2025 Article: 87
Epigenetic profiles integrated with transcriptomic reveal the difference between COPD and PRISm in KOCOSS-NIH Eun-A ChoiHyun Jeong KimHye-Ja Lee Research Open access 10 April 2025 Article: 86
Roles of Immunity and Endogenous Retroelements in the Pathogenesis of Rheumatoid Arthritis and Treatment Strategies Mingyang LiYuanyuan SunDong Niu Review 09 April 2025 Article: 85
Autoimmune mechanisms and inflammation in obesity-associated type 2 diabetes, atherosclerosis, and non-alcoholic fatty liver disease Yuanyuan SunXueting ShanDong Niu Review 09 April 2025 Article: 84
Can the molecular and transgenic breeding of crops be an alternative and sustainable technology to meet food demand? Celeste Gracia-RodriguezAngela Elena Martínez-MedinaNagamani Balagurusamy Review 09 April 2025 Article: 83
Comprehensive analysis of orthologous genes reveals functional dynamics and energy metabolism in the rhizospheric microbiome of Moringa oleifera Fatmah O. SefrjiAala A. AbulfarajAbeer S. Aloufi Research Open access 07 April 2025 Article: 82
The miRNomics of antiretroviral therapy-induced obesity Niska MajumdarBishwa R. PokharelShaw M. Akula Review Open access 05 April 2025 Article: 81
Role of non-coding RNAs in quality improvement of horticultural crops: computational tools, databases, and algorithms for identification and analysis Tanzeel BashirAmjad M. Husaini Review 04 April 2025 Article: 80
In silico analysis of betaine aldehyde dehydrogenase (BADH) gene in different cultivars of Chenopodium quinoa Ali Reza MirzaeiBahman Fazeli-NasabMansour Ghorbanpour Research 02 April 2025 Article: 79
Metabolic engineering of lipids for crop resilience and nutritional improvements towards sustainable agriculture Swati ManglaYogesh K. AhlawatSumati Choubey Review 01 April 2025 Article: 78
Emerging role and clinical applications of circular RNAs in human diseases Subhayan SurJayanta K. PalRiddhiman Bhattacharyya Review 28 March 2025 Article: 77
Dynamic cellular composition and immune landscape revealed by single-cell transcriptome profiling in a brain arteriovenous malformation Yutong LiuHongchuan NiuYuanli Zhao Brief Report 27 March 2025 Article: 76
A new perspective on endometriosis: Integrating eQTL mendelian randomization with transcriptomics and single-cell data analyses Sheng DouYi WeiJunli Wang Research Open access 26 March 2025 Article: 75
Identification of the STY13 gene family across the entire genome and an analysis of the essential function of GhSTY13-12 in cotton’s response to abiotic stress Shaoliang ZhangHuiyun ShanShoulin Hu Research 26 March 2025 Article: 74
Linking genomic and proteomic signatures to brain amyloid burden: insights from GR@ACE/DEGESCO Raquel PuertaItziar de Rojasfor the Alzheimer’s Disease Neuroimaging Initiative Research Open access 25 March 2025 Article: 73
New approaches of chimeric antigen receptor (CAR)-immune cell-based therapy in gastric cancer; highlight CAR-T and CAR-NK Saade Abdalkareem JasimHarikumar PallathadkaAhmed Hussein Zwamel Review 25 March 2025 Article: 72
Cutting edge: ferroptosis in metabolic dysfunction-associated steatotic liver disease (MASLD) pathogenesis and therapy Amr Ali Mohamed Abdelgawwad El-SehrawyTeeba Ammar RashidAbed J. Kadhim Review 25 March 2025 Article: 71
Comprehensive study of tRNA-derived fragments in plants for biotic stress responses Supriya P. SwainNiyati BishtShailesh Kumar Research 25 March 2025 Article: 70
Correction to: Integrative single-cell and bulk RNA-seq analysis identifies lactylation-related signature in osteosarcoma Zhou XieXiao QuXiaoji Luo Correction 24 March 2025 Article: 69
DUBR non-coding RNA regulates gene expression by affecting AP-1 enhancer accessibility Simone D. HallKhoa TranColleen A. McHugh Research Open access 21 March 2025 Article: 68
CutIn: a ready-to-use construct for rapid generation of urgently needed transgenic cell lines in emerging infection research Liangliang ZhangDandan LiJunnan Lu Research 20 March 2025 Article: 67
Discovery of circular transcripts of the human BCL2-like 12 (BCL2L12) apoptosis-related gene, using targeted nanopore sequencing, provides new insights into circular RNA biology Paraskevi KarousiChristos K. KontosAndreas Scorilas Research Open access 19 March 2025 Article: 66
NEDD4 facilitates the progression of endometrial carcinoma by enhancing PAMR1 protein degradation through ubiquitination Hongbo GuoHongping TangGuangwu Zhang Research 15 March 2025 Article: 65
Combined transcriptomic and proteomic analyses reveal relevant myelin features in mice with ischemic stroke Qiuyang QianHao LyuMei Shen Research Open access 14 March 2025 Article: 64
Single-cell RNA sequencing revealed changes in the tumor microenvironment induced by radiotherapy for cervical cancer and the molecular mechanism of mast cells in immunosuppression Lujiadai XueLinzhi GaoXiaoyu Wang Research 14 March 2025 Article: 63
Predictive and personalized approaches for idiopathic pulmonary fibrosis: a Wnt-related gene set scoring framework integrating single-cell sequencing, spatial transcriptomics, and machine learning for diagnosis and prognosis Qijian JiLei JiangJiwei Hou Correspondence 13 March 2025 Article: 62
Differential miRNA expression and regulatory mechanisms in pigmentation and fiber development of white and brown cotton (Gossypium hirsutum) Sagar Prasad NayakPriti PrasadChandra Sekhar Mohanty Research 12 March 2025 Article: 61
Integrative single-cell and bulk RNA-seq analysis identifies lactylation-related signature in osteosarcoma Zhou XieXiao QuXiaoji Luo Research 12 March 2025 Article: 60
MAZ-mediated LAMA5 transcription activation promotes gastric cancer progression through the STAT3 signaling Yu WangJiazhong XuQinhui Sun Research Open access 12 March 2025 Article: 59
Regulatory dynamics of Nanog in chondrocyte dedifferentiation: role of KLF4/p53 and p38/AKT signaling Young Seok EomSong Ja Kim Research 11 March 2025 Article: 58
Genome-wide identification of F-box-LRR gene family and the functional analysis of CsFBXL13 transcription factor in tea plants Xiangya DouSiyi XieNa Tian Research 10 March 2025 Article: 57
Transcriptomic profiling reveals mechanism, therapeutic potential, and prognostic value of cancer stemness characteristic in nasopharyngeal carcinoma Jin-Wei ChenRun-Nan ShenCheng-Peng Gui Research 07 March 2025 Article: 56
Transcriptome analysis of the hypothalamus and testes in Brandt’s Vole: new insights into mechanisms of photoperiodic plasticity in postnatal testicular development Lewen WangYaqi YingDawei Wang Research 07 March 2025 Article: 55
Pan-cancer investigation regarding the prognostic predictive and immunological regulation functions of PGK1 and experimental validation in esophageal squamous cell carcinoma Junru ChenXun WuQuanlin Guan Research 06 March 2025 Article: 54
Polycomb repressive complex 2 (PRC2) pathway’s role in cancer cell plasticity and drug resistance Pouya GoleijMohammad Mahdi HeidariHaroon Khan Review 06 March 2025 Article: 53
Molecular signatures that translate across omics layers and crops under high aluminium and low phosphorus stress facilitate the identification of reliable molecular targets for genotyping in lentil Kadiyala KavyaNoren Singh KonjengbamAjay Kumar Mahato Research 05 March 2025 Article: 52