- Very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need
- Connection to large database on sex differences in drug effects
- Clear key note messages by international experts
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- About this book
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This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effects that represents cutting edge science and includes interaction of drugs with sex hormones, genomic and epigenetic mechanisms. It also covers S/G in drug development, in animal models and clinical development and S/G in drug prescriptions. Part II targets S/G differences in drug effects in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic diseases, in cancer, inflammation, and rheumatic diseases, in bacterial and retroviral infections, thrombosis, embolism. New drugs will be discussed.
- Table of contents (24 chapters)
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Sex and Gender Differences in Clinical Medicine
Pages 3-22
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Sex Differences in Animal Models for Cardiovascular Diseases and the Role of Estrogen
Pages 23-48
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Sex Differences at Cellular Level: “Cells Have a Sex”
Pages 49-65
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What a Difference an X or Y Makes: Sex Chromosomes, Gene Dose, and Epigenetics in Sexual Differentiation
Pages 67-88
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Sex Differences in Drug Effects: Interaction with Sex Hormones in Adult Life
Pages 91-105
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Table of contents (24 chapters)
- Download Preface 1 PDF (22.9 KB)
- Download Sample pages 1 PDF (335.5 KB)
- Download Table of contents PDF (24.2 KB)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Sex and Gender Differences in Pharmacology
- Editors
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- Vera Regitz-Zagrosek
- Series Title
- Handbook of Experimental Pharmacology
- Series Volume
- 214
- Copyright
- 2012
- Publisher
- Springer-Verlag Berlin Heidelberg
- Copyright Holder
- Springer-Verlag Berlin Heidelberg
- eBook ISBN
- 978-3-642-30726-3
- DOI
- 10.1007/978-3-642-30726-3
- Hardcover ISBN
- 978-3-642-30725-6
- Softcover ISBN
- 978-3-642-42802-9
- Series ISSN
- 0171-2004
- Edition Number
- 1
- Number of Pages
- X, 602
- Topics
