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Handbook of Experimental Pharmacology

Pharmacology of Neurotransmitter Release

Editors: Südhof, Thomas C., Starke, Klaus (Eds.)

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  • Analyses the molecular events of exocytosis

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  • ISBN 978-3-540-74805-2
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About this book

It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. This includes a discussion of presynaptic calcium channels, the core proteins of the secretory machinery, and the actions of clostridial toxins and a -latrotoxin, famous for their potency as well as their crucial role in the elucidation of the steps of exocytosis. In the book’s second part, the presynaptic receptors for endogenous chemical signals are presented that make neurotransmitter release a highly regulated process. These include ligand-gated ion channels and presynaptic G-protein-coupled receptors. The targets of presynaptic receptors within the exocytosis cascade, and their therapeutic potential, are subjects addressed in the majority of chapters.

Table of contents (17 chapters)

Table of contents (17 chapters)

Buy this book

eBook 214,19 €
price for Spain (gross)
  • ISBN 978-3-540-74805-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 291,19 €
price for Spain (gross)
  • ISBN 978-3-540-74804-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
Softcover 272,14 €
price for Spain (gross)
  • ISBN 978-3-642-09424-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
Pharmacology of Neurotransmitter Release
Editors
  • Thomas C. Südhof
  • Klaus Starke
Series Title
Handbook of Experimental Pharmacology
Series Volume
184
Copyright
2008
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-540-74805-2
DOI
10.1007/978-3-540-74805-2
Hardcover ISBN
978-3-540-74804-5
Softcover ISBN
978-3-642-09424-8
Series ISSN
0171-2004
Edition Number
1
Number of Pages
XIV, 582
Topics