Overview
- Editors:
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Christof M. Niemeyer
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Fachbereich Chemie der Universität Dortmund, Dortmund, Germany
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Table of contents (23 protocols)
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Glycosyl and Lipid Conjugates
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- Thomas Durek, Roger S. Goody, Kirill Alexandrov
Pages 233-244
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- Melanie Wagner, Jürgen Kuhlmann
Pages 245-254
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- Thomas J. Tolbert, Chi-Huey Wong
Pages 255-266
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- Thomas J. Tolbert, Chi-Huey Wong
Pages 267-279
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Biofunctionalization of Surfaces
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Front Matter
Pages 281-281
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- Anette Jacob, Ole Brandt, Achim Stephan, Jörg D. Hoheisel
Pages 283-293
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- Pompi Hazarika, Tatiana Giorgi, Martina Reibner, Buelent Ceyhan, Christof M. Niemeyer
Pages 295-304
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Back Matter
Pages 321-330
About this book
There are a number of outstanding volumes that provide a comprehensive overview of bioconjugation techniques. However, many of the conventional approaches to the synthesis of chemically modified protein conjugates lack efficient means to control the stoichiometry of conjugation, as well as the s- cific site of attachment of the conjugated moiety. Moreover, the recent dev- opments in microarray technologies as well as in nanobiotechnology—a novel field of research rapidly evolving at the crossroads of physics, chemistry, b- technology, and materials science—call for a summary of modern bioconjugation strategies to overcome the limitations of the classical approaches. Bioconjugation Protocols: Methods and Strategies is intended to provide an update of many of the classic techniques and also to introduce and summarize newer approaches that go beyond the pure biomedical applications of bioconjugation. The purpose of Bioconjugation Protocols: Methods and Str- egies is therefore to provide instruction and inspiration for all those scientists confronting the challenges of semisynthesizing functional biomolecular reagents for a wide variety of applications ranging from novel biomedical diagnostics, to therapeutics, to biomaterials. Part I contains seven protocols for the preparation of protein conjugates.
Reviews
"...provides highlights for scientists who are pioneering in the synthesis of biofunctional macromolecules, as well as providing resources to all levels of scientists who are engaged in the fields of diagnostics, biomaterials, and pharmacotherapeutics." - Journal of Medicinal Chemistry
Editors and Affiliations
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Fachbereich Chemie der Universität Dortmund, Dortmund, Germany
Christof M. Niemeyer