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Cell Culture Engineering IV

Improvements of Human Health

  • Book
  • © 1995

Overview

Editors:
  1. Barry C. Buckland

    1. Merck Research Laboratories, Biochemical Process R&D, Rahway, USA

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  2. John G. Aunins
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  3. Theodora A. Bibila
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  4. Wei-Shou Hu
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  5. David K. Robinson
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  6. Weichang Zhou
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Part of the book series: Current Applications of Cell Culture Engineering (CACC, volume 1)

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Table of contents (39 chapters)

  1. Evaluation of monitoring approaches and effects of culture conditions on recombinant protein production in baculovirus-infected insect cells

    • William T. Hensler, Spiros N. Agathos
    Pages 177-186

  2. The analysis of protein pharmaceuticals: Near future advances

    • C. Russell Middaugh
    Pages 187-194

  3. The effect of protein synthesis inhibitors on the glycosylation site occupancy of recombinant human prolactin

    • Marc Shelikoff, A. J. Sinskey, Gregory Stephanopoulos
    Pages 195-208

  4. Effect of lipid supplements on the production and glycosylation of recombinant interferon-γ expressed in CHO cells

    • Nigel Jenkins, Paula Castro, Sunitha Menon, Andrew Ison, Alan Bull
    Pages 209-215

  5. Role of environmental conditions on the expression levels, glycoform pattern and levels of sialyltransferase for hFSH produced by recombinant CHO cells

    • W. Chotigeat, Y. Watanapokasin, S. Mahler, P. P. Gray
    Pages 217-221

  6. Glycosylation and functional activity of anti-D secreted by two human lymphoblastoid cell lines

    • Diane Cant, John Barford, Colin Harbour, Anne Fletcher, Nicole Packer, Andrew Gooley
    Pages 223-228

  7. Interaction of cell culture with downstream purification: a case study

    • Wolf Berthold, Ralph Kempken
    Pages 229-242

  8. Evaluation of membranes for use in on-line cell separation during mammalian cell perfusion processes

    • Heino Büntemeyer, Christoph Böhme, Jürgen Lehmann
    Pages 243-251

  9. Vortex flow filtration of mammalian and insect cells

    • Steven J. Hawrylik, David J. Wasilko, Joann S. Pillar, John B. Cheng, S. Edward Lee
    Pages 253-258

  10. Automated imunoanalysis systems for monitoring mammalian cell cultivation processes

    • Birgitt Schulze, Cornelia Middendorf, Martin Reinecke, Thomas Scheper, Wolfgang Noé, Michael Howaldt
    Pages 259-269

  11. A direct computer control concept for mammalian cell fermentation processes

    • Heino Büntemeyer, Rainer Marzahl, Jürgen Lehmann
    Pages 271-279

  12. Automated monitoring of cell concentration and viability using an image analysis system

    • Fumio Maruhashi, Sei Murakami, Kenji Baba
    Pages 281-289

  13. Software sensors for the monitoring of perfusion cultures: Evaluation of the hybridoma density and the medium composition from glucose concentration measurements

    • François Pelletier, Christian Fonteix, Aurélio Lourenço da Silva, Annie Marc, Jean-Marc Engasser
    Pages 291-299

  14. Design of a bubble-swarm bioreactor for animal cell culture

    • F. Gudermann, D. Lütkemeyer, J. Lehmann
    Pages 301-309

  15. Cells and bubbles in sparged bioreactors

    • Jeffrey J. Chalmers
    Pages 311-320

  16. Quantitative investigations of cell-bubble interactions using a foam fractionation technique

    • W. S. Tan, G. C. Dai, Y. L. Chen
    Pages 321-328

  17. Prediction of mechanical damage to animal cells in turbulence

    • C. R. Thomas, M. Al-Rubeai, Z. Zhang
    Pages 329-335

  18. Repeated-batch cultures of Baby Hamster Kidney cell aggregates in stirred vessels

    • J. L. Moreira, A. S. Feliciano, P. C. Santana, P. E. Cruz, J. G. Aunins, M. J. T. Carrondo
    Pages 337-349

  19. Towards the development of a bioartificial pancreas: immunoisolation and NMR monitoring of mouse insulinomas

    • A. Sambanis, K. K. Papas, P. C. Flanders, R. C. Long Jr., H. Kang, I. Constantinidis
    Pages 351-363

  20. Overview of a quality assurance/quality control compliance program consistent with FDA regulations and policies for somatic cell and gene therapies: a four year experience

    • Gary C. du Moulin, Zorina Pitkin, Yuan-Jin Shen, Evelyn Conti, Jean Ko Stewart, Carla Charles et al.
    Pages 365-372
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Keywords

About this book

Cell Culture Engineering IV, Improvements of Human Health covers the latest approaches to improving the cell host through improved understanding of the molecular biology, the development of novel vaccines, approaches to bioreactor design and operation, monitoring techniques in process control and quality related topics. The work was carefully put together as one result of the Cell Culture Engineering IV Meeting held in San Diego, U.S.A. in 1994, however, the book may not be perceived as a proceedings volume - the criteria of the book series apply.
For cell biologists, biochemists, molecular biologists, immunologists and other disciplines related to cell culture engineering, working in the academic environment, as well as in (biotechnology or pharmaceutical) industry.

Editors and Affiliations

  • Merck Research Laboratories, Biochemical Process R&D, Rahway, USA

    Barry C. Buckland

Bibliographic Information

  • Book Title: Cell Culture Engineering IV

  • Book Subtitle: Improvements of Human Health

  • Editors: Barry C. Buckland, John G. Aunins, Theodora A. Bibila, Wei-Shou Hu, David K. Robinson, Weichang Zhou

  • Series Title: Current Applications of Cell Culture Engineering

  • DOI: https://doi.org/10.1007/978-94-011-0257-5

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 1995

  • Hardcover ISBN: 978-0-7923-3353-1Published: 31 January 1995

  • Softcover ISBN: 978-94-010-4114-0Published: 13 November 2012

  • eBook ISBN: 978-94-011-0257-5Published: 29 June 2013

  • Series ISSN: 1386-2928

  • Edition Number: 1

  • Number of Pages: V, 376

  • Topics: Animal Anatomy / Morphology / Histology, Animal Biochemistry, Biotechnology

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