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Helicobacter pylori Research

From Bench to Bedside

  • Book
  • © 2016

Overview

  • Presents in a single volume an up-to-date summary of both basic science and clinical research with actual practical consequences.
  • Provides population-based strategies for H. pylori-associated disease management including European, Latin American, and Asian perspectives.
  • Covers the roles of all reported virulence factors of H. pylori on pathogenesis

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Table of contents (25 chapters)

  1. Bacteriology and Molecular Biology

  2. Immune Responses and Host Factors

  3. Helicobacter pylori-Associated Diseases

Keywords

About this book

This book provides the current updated knowledge on all essential aspects in the rapidly evolving area of Helicobacter pylori research. H. pylori is a class I carcinogen and one of the most common infections in the world. While most people colonized by H. pylori will remain asymptomatic, up to 20 % of them may develop serious gastroduodenal disease such as peptic ulcers or gastric cancer. H. pylori is the only known bacterium linked to the development of cancer and consequently is an important focus of research. Outstanding international experts from diverse scientific disciplines contribute here to give detailed insights into the current understanding concerning the physiology and role of this pathogen. Both basic science and clinical research with actual practical consequences are taken into account. The chapters target microbiology, epidemiology, genetics, biochemistry, interactions with the immune system, signal transduction, pathogenic mechanisms inthe gastroduodenal mucosa, gastric disease development, and therapy including antibiotics or probiotics treatment as well as vaccination strategies. This book is an important reference not only for clinicians but also microbiologists. It provides in a single volume an up-to-date summary of our current knowledge of this microbe and the multiple ways in which it impacts upon public health in all parts of the world.

Reviews

“This is an in-depth review of the new and evolving research into Helicobacter pylori. The purpose is to help readers better understand a complex organism that can cause many people gastrointestinal issues and the future of treatment. The audience is gastroenterologists and researchers with a keen interest in H.pylori. … This well-done book discusses many important topics related to H.pylori research, and provides a better understanding of this important organism.” (Noah Settergren, Doody's Book Reviews, March, 2016)

Editors and Affiliations

  • Division of Microbiology;Dept of Biology, Friedrich Alexander Univ;Erlangen-Nuremb, Erlangen, Germany

    Steffen Backert

  • Dept of Medicine-Gastroenteology, Baylor College of Medicine, Houston, USA

    Yoshio Yamaoka

Bibliographic Information

  • Book Title: Helicobacter pylori Research

  • Book Subtitle: From Bench to Bedside

  • Editors: Steffen Backert, Yoshio Yamaoka

  • DOI: https://doi.org/10.1007/978-4-431-55936-8

  • Publisher: Springer Tokyo

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Japan 2016

  • Hardcover ISBN: 978-4-431-55934-4Published: 17 May 2016

  • Softcover ISBN: 978-4-431-56731-8Published: 27 May 2018

  • eBook ISBN: 978-4-431-55936-8Published: 09 May 2016

  • Edition Number: 1

  • Number of Pages: XI, 613

  • Number of Illustrations: 5 b/w illustrations, 52 illustrations in colour

  • Topics: Medical Microbiology, Immunology, Gastroenterology, Bacteriology

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