Overview
- Editors:
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Konrad Schwemmle
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Allgemeinchirurgische Klinik des Zentrums für Chirurgie, Justus-Liebig-Universität, Giessen, Germany
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Karl Aigner
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Allgemeinchirurgische Klinik des Zentrums für Chirurgie, Justus-Liebig-Universität, Giessen, Germany
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Table of contents (47 chapters)
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Vascular Perfusion in Cancer Therapy of the Extremities
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- A. Azzarelli, L. Gennari, G. Bonfanti, R. Audisio, V. Quagliuolo
Pages 218-221
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Back Matter
Pages 222-222
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Isolated Perfusion of the Extremities
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- H. Schraffordt Koops, J. Oldhoff
Pages 223-228
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- J. Tonak, W. Hohenberger, F. Weidner, H. Göhl
Pages 229-238
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- K. Aigner, P. Hild, K. Henneking, E. Paul, M. Hundeiker
Pages 239-245
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- E. Paul, M. Ishii, K. Aigner, P. Hild, L. Illig
Pages 246-253
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- K. Henneking, K. Aigner, C. Deeg, G. Merker, H. W. Spelz, M. Hundeiker
Pages 254-259
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- R. P. Braat, J. Wieberdink, E. van Slooten, G. Olthuis
Pages 260-263
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- O. Busse, K. Aigner, H. Wilimzig
Pages 264-267
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- F. J. Lejeune, T. Deloof, P. Ewalenko, J. Fruhling, M. Jabri, M. Mathieu et al.
Pages 268-276
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- P.-E. Jönsson, L. Hafström, A. Hugander
Pages 277-282
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Back Matter
Pages 289-298
About this book
Substantial relief of discomfort may be anticipated by most patients suffering from pelvic and lower-extremity pain who are treated by arterial infusion of nitrogen mustard. Seventy-three patients with intractable pain secondary to malignancy arising in the pelvis received 83 percutaneous pelvic arterial infusions of this drug. Sixty infusions (72%) resulted in marked relief from pain for periods averaging 6-8 weeks. Advantages of the procedure are low toxicity, relative simplicity and availability of technique, and an acceptable rate of complications with minimal morbidity. Patients experiencing satisfactory results may expect significant relief from a second infusion for recurrent pain. The most rewarding result is the freedom from the cyclic return of pain characterized by oral and intramuscular analgesic therapy. Little or no relief can be expected in patients with pain caused by compression fractures of the vertebrae, or where the tumor burden is so great that adequate perfusion of the involved nerves is not possible. One should consider this procedure for controlling pain before resorting to the more dangerous and potentially disabling techniques of spinal cordotomy or intrathecal alcohol injection. References Bateman JR, Hazen JG, Stolinsky DC, Steinfeld JL (1966) Advanced carcinoma of the cervix treated by intra-arterial methotrexate. Am J Obstet Gynecol 96: 181-187 Calabresi P, Parks RW Jr (1970) Alkylating agents, antimetabolites, hormones. and other antiproliferative agents. In: Goodman LS, Gilman A (eds) The pharmacological basis of therapeutics, 4th edn.