Overview
- Editors:
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Chris H. M. M. Bruyn
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University of Nijmegen Faculty of Medicine, Nijmegen, The Netherlands
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H. Anne Simmonds
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Guy’s Hospital Medical School, London, UK
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Mathias M. Müller
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University of Vienna, Vienna, Austria
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Table of contents (105 chapters)
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Genetic and Molecular Studies
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- Patricia A. Hoffee, Stephen W. Hunt III
Pages 405-410
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- A. C. Chinault, J. Brennand, D. S. Konecki, R. L. Nussbaum, C. T. Caskey
Pages 411-415
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- R. L. Nussbaum, C. T. Caskey, F. Gilbert, W. Nyhan
Pages 417-420
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Regulatory Mechanisms
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De Novo Purine Synthesis
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- Peter B. Rowe, Eric McCairns, Dorit Sauer, Dale Fahey
Pages 421-426
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- Michele J. Losman, Michael A. Becker
Pages 427-432
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- M. Pizzichini, A. Di Stefano, G. Bruni, R. Leoncini, E. Marinello
Pages 433-436
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- F. Aleo, S. Comandé, R. Marcolongo, E. Marinello, U. Valentini
Pages 437-440
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- Milton W. Taylor, Suman Olivelle, Kathy Coy, Roy A. Levine, Howard Hershey
Pages 441-447
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- Mary M. Welch, Frederick B. Rudolph
Pages 449-452
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- Mitsuo Itakura, Kamejiro Yamashita
Pages 453-456
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Purine Interconversions and Catabolism
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- Jason Faller, Irving H. Fox
Pages 457-462
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- G. Van den Berghe, F. Bontemps, H. G. Hers
Pages 463-468
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- M.-F. Vincent, G. Van den Berghe, H. G. Hers
Pages 469-474
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- F. Bontemps, G. Van den Berghe, H. G. Hers
Pages 475-480
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- S. Brosh, P. Boer, O. Sperling
Pages 481-485
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- J. Barankiewicz, P. Tysarowski, P. Chomczynski
Pages 487-492
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- J. Rigau-Lloveras, E. Olivé-Morros, M. P. Rivera-Fillat, M. R. Grau-Oliete
Pages 493-496
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- Laureen Kurpis, David John, Irving H. Fox
Pages 497-500
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- Gianni Marone, Rosaria Petracca, Mario Condorelli
Pages 501-509
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- Dennis J. Levinson, Douglas E. Decker
Pages 511-517
About this book
These two volumes, entitled "Purine Metabolism in Man IV" con tain the paper presented at the "IV. International Symposium on Human Purine and Pyrimidine Metabolism," held in Maastricht (The Netherlands), June 1982. The proceedings of the three previous meet ings in Tel Aviv (Israel, 1973), Baden (Austria, 1976) and Madrid (Spain, 1979) were also published by Plenum Press. In the past few years interest in purine and pyrimidine metabo lism under normal and pathological conditions has been growing rapid ly. Apart from the more or less classical topics such as hyperuricae mia, clinical gout and urolithiasis, an increasing number of papers relating to other fields have been presented at successive meetings. Knowledge derived from the study of purine metabolism in relation to lymphocyte function, for instance, has opened up new possibilities for immunomodulation and leukaemia chemotherapy, with eventual conse quences for other types of cancer. At previous meetings there have been pointers implicating purine metabolism in relation to normal cardiac and skeletal muscle function. During the present meeting much new data on both issues have been re ported which indicate clear differences in the pathways of ATP metabo lism. The widening of the field of interest is also illustrated by the recent work on infectious disease: exploitation of the differences in purine metabolic pathways in certain parasites compared with those in human cells has resulted in new rationales for therapy being devel oped.
Editors and Affiliations
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University of Nijmegen Faculty of Medicine, Nijmegen, The Netherlands
Chris H. M. M. Bruyn
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Guy’s Hospital Medical School, London, UK
H. Anne Simmonds
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University of Vienna, Vienna, Austria
Mathias M. Müller