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DNA Repair Mechanisms and Their Biological Implications in Mammalian Cells

  • Book
  • © 1989

Overview

Editors:
  1. Muriel W. Lambert

    1. New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, USA

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  2. Jacques Laval

    1. Institut Gustave Roussy, Villejuif, France

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: NATO Science Series A: (NSSA, volume 182)

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Table of contents (51 chapters)

  1. Mutagenesis

    1. Deoxyribonucleotide Pools, DNA Repair and Mutagenesis

      • Andrew R. Collins, Diane T. Black
      Pages 211-220

  2. Recombination and Mismatch Repair

    1. Duplex-Duplex Homologous Recombination Catalysed by a Human Nuclear Extract. Involvement in Double-Strand Break Repair

      • Bernard Lopez, Jacques Coppey
      Pages 221-231

    2. Proteins from Yeast and Human Cells Specific for Model Holliday Junctions in DNA

      • Stephen C. West, Kieran M. Elborough, Carol A. Parsons, Steven M. Picksley
      Pages 233-243

    3. Characterization of a Strand Transferase Activity from Human Cells

      • Era Cassuto, Paul Howard-Flanders
      Pages 245-253

    4. Mismatch Repair in Mammalian Cells: Approaches to the in Vitro Study of DNA Mismatch Correction Reactions

      • William C. Summers, Peter M. Glazer
      Pages 255-261

    5. Mismatch Repair Patterns in Simian Cells Correlate with the Specificity of a Mismatch Binding Protein Isolated from Simian and HeLa Cells

      • J. Jiricny, T. C. Brown, N. Corman, B. B. Rudkin
      Pages 263-270

  3. Chromatin Proteins and Chromatin Structure in DNA Repair

    1. DNA Excision Repair at the Nucleosome Level of Chromatin

      • Michael J. Smerdon
      Pages 271-294

    2. Modulation of Activity of Human Chromatin-Associated Endonucleases on Damaged DNA by Nucleosome Structure

      • Muriel W. Lambert, David D. Parrish
      Pages 295-324

    3. Relationships Between DNA Repair and Transcription in Defined DNA Sequences in Mammalian Cells

      • Philip Hanawalt, Isabel Mellon, David Scicchitano, Graciela Spivak
      Pages 325-337

    4. Non-Random Distribution of UV-Induced Repair in Higher-Order Chromatin Loops in Human Cells and its Relationship to Preferential Repair of Active Genes

      • L. H. F. Mullenders, J. Venema, L. Mayne, A. T. Natarajan, A. A. van Zeeland
      Pages 339-348

    5. Electron Microscopic Visualization of Chromatin Structure at Sites of DNA Excision Repair Following Ultraviolet Irradiation of Cultured Human Fibroblasts

      • B. J. Gowans, G. de Murcia, D. J. Hunting
      Pages 349-364

    6. Poly (ADP-Ribosyl) Ation Reactions and Modulation of Chromatin Structure

      • Gilbert de Murcia, Gérard Gradwohl, Alice Mazen, Josiane Ménissier-de Murcia, Ann Huletsky, Guy Poirier
      Pages 365-377

    7. Variation of Nuclear ADP-Ribosyl Transferase in Rat Liver Carcinogenesis and in Synchronized HeLa Cells

      • U. Bertazzoni, C. F. Cesarone, R. Izzo, L. Scarabelli, I. Colombo, M. Orunesu et al.
      Pages 379-389

    8. DNA Repair Processes in Mutant Cells Deficient in Poly (ADP-Ribose) Synthesis

      • Nathan A. Berger, Satadal Chatterjee, Ming-Feng Cheng, Denise Meckler, Shirley J. Petzold, Sosamma J. Berger
      Pages 391-397

  4. Repair Defective Cell Types

    1. Co-Recessive Inheritance: A Model for Diseases Associated with Defective DNA Repair

      • W. Clark Lambert, Muriel W. Lambert
      Pages 399-428

    2. Mammalian DNA Ligases and the Molecular Defect in Bloom’s Syndrome

      • Tomas Lindah, Anne E. Willis, Dana D. Lasko, Alan Tomkinson
      Pages 429-438

    3. Detection of Unique Antigenic Lesions in the Uracil DNA Glycosylase from Bloom’s Syndrome

      • Michael A. Sirover, Gita Seal, Thomas M. Vollberg, Barbara L. Cool, Kilian Brech, Seth J. Karp
      Pages 439-459

    4. DNA Ligase Activity in Human Cells from Normal Donors and from Patients with Bloom’s Syndrome and Fanconi’s Anemia

      • Mauro Mezzina, Silvano Nocentini, Jeannette Nardelli, A. Ivana Scovassi, Umberto Bertazzoni, Alain Sarasin
      Pages 461-469

    5. Processing of Photoinduced Cross-Links and Monoadducts in Human Cell DNA: Genetic and Molecular Features

      • E. Moustacchi, D. Papadopoulo, D. Averbeck, D. Fraser, C. Diatloff-Zito
      Pages 471-482

    6. Parallels Between Nucleotide Excision Repair in Human Cells and E. Coli

      • Richard D. Wood
      Pages 483-488
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Keywords

About this book

This volume contains edited contributions from the speakers at the NATO Advanced Research Workshop on "DNA Repair Mechanisms and Their Biological Implications in Mammalian Cells" held October 1-6, 1988, at the Abbaye Royale de Fontevraud, Fontevraud France. The meeting was dedicated to Paul Howard-Flanders (Yale University, New Haven, CT. , 1919-1988), whose seminal con­ tributions to the DNA repair field include the cO-discovery of the excision repair pathway, the elucidation of post-repli­ cation repair in E. coli, the isolation of the lexA and recC mutants, and his extensive work on the enzymology of RecA. A plethora of recent developments in DNA repair mechan­ isms and related processes in mammalian cells have advanced our understanding of this field in a number of different areas and have given new emphasis to the ways these systems both resemble DNA repair processes in other groups of organisms in some respects yet are strikingly different from them in others. Within the past decade there have been a number of international conferences on DNA damage and repair mechanisms but none has been focused on these processes in mammalian cells.

Editors and Affiliations

  • New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, USA

    Muriel W. Lambert

  • Institut Gustave Roussy, Villejuif, France

    Jacques Laval

Bibliographic Information

  • Book Title: DNA Repair Mechanisms and Their Biological Implications in Mammalian Cells

  • Editors: Muriel W. Lambert, Jacques Laval

  • Series Title: NATO Science Series A:

  • DOI: https://doi.org/10.1007/978-1-4684-1327-4

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1989

  • Softcover ISBN: 978-1-4684-1329-8Published: 16 December 2012

  • eBook ISBN: 978-1-4684-1327-4Published: 09 March 2013

  • Edition Number: 1

  • Number of Pages: XVI, 667

  • Topics: Biochemistry, general

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