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ADP-Ribose Transfer Reactions

Mechanisms and Biological Significance

  • Book
  • © 1989

Overview

Editors:
  1. Myron K. Jacobson

    1. Department of Biochemistry, Texas College of Osteopathic Medicine, Fort Worth, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Elaine L. Jacobson

    1. Department of Medicine, Texas College of Osteopathic Medicine, Fort Worth, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

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Table of contents (96 chapters)

  1. Enzymology of ADP-Ribosylation

    1. Alteration of Poly(ADP-Ribose) Metabolism by Ethanol: Kinetic Mechanism of Action

      • James L. Sims, Robert C. Benjamin
      Pages 105-108

    2. The Effect of Benzamides on the Activity of Nuclear ADP-Ribosyl Transferase and the Accumulation of Poly(ADP-Ribose) In Vivo

      • Christopher J. Skidmore, Janet Jones, Bhartiben N. Patel
      Pages 109-112

    3. Carba-Nicotinamide Adenine Dinucleotide: Synthesis and Enzymological Application of a Novel Inhibitor of ADP-ribosyl Transfer

      • James T. Slama, Anne M. Simmons
      Pages 113-118

    4. Purification and Properties of Two Forms of Poly(ADP-Ribose) Glycohydrolase

      • Sei-ichi Tanuma
      Pages 119-124

    5. Poly(ADP-Ribosyl)ation in Free Cytoplasmic mRNA-Protein Complexes

      • Hélène Thomassin, Paul Mandel
      Pages 125-129

    6. New Inhibitors of Poly(ADP-Ribose) Synthetase

      • Marek Banasik, Hajime Komura, Isao Saito, Nazar A. N. Abed, Kunihiro Ueda
      Pages 130-133

    7. Monoclonal Antibodies to Human Placental Poly(ADP-Ribose) Synthetase

      • Hiroshi Ushiro, Yutaka Shizuta
      Pages 134-138

    8. Characterization of the Human Autoantibody Response to Poly(ADP-Ribose) Polymerase

      • Hisashi Yamanaka, Erik H. Willis, Carol A. Penning, Carol L. Peebles, M. Tan, Dennis A. Carson
      Pages 139-144

    9. In Vivo Automodification of Poly(ADP-Ribose) Polymerase and DNA Repair

      • Jingyuan Zhang, Ramaswami Kalamegham, Kaney Ebisuzaki
      Pages 145-150

  2. ADP-Ribosylation and Chromatin Function

    1. ADP-Ribosylation and Chromatin Function

      • Felix R. Althaus, Georg Mathis, Rafael Alvarez-Gonzalez, Pius Loetscher, Marianne Mattenberger
      Pages 151-157

    2. Modulation of Chromatin Structure by Poly(ADP-Ribosyl)ation

      • Ann Huletsky, Gilbert de Murcia, Sylviane Muller, Daniel Lamarre, Michel Hengartner, Guy Poirier
      Pages 158-164

    3. Automodified Poly(ADP-Ribose) Synthetase Detected in Rat Liver Cells is Selectively Attached to a Nuclear Matrix-Like Structure

      • Martin Brauer, Jutta Witten, Peter Adamietz
      Pages 165-172

    4. Studies on the Nuclear Distribution of ADP-Ribose Polymers

      • Maria E. Cardenas-Corona, Elaine L. Jacobson, Myron K. Jacobson
      Pages 173-178

    5. A Proposed Molecular Mechanism of Nucleosome Unfolding. Effect of Poly(ADP-Ribose) on DNA-Histone H4 Interaction

      • Georg Sauermann, Jozefa Wesierska-Gadek
      Pages 179-183

    6. On The Nature of the Interaction Between Poly(ADP-Ribose) Polymerase and DNA

      • Srinivas S. Sastry, Ernest Kun
      Pages 184-188

    7. Inhibition of ADP-Ribosyl Transferase Activity Blocks the Stable Integeration of Transfected DNA into the Mammalian Cell Genome

      • Farzin Farzaneh, George N. Panayotou, Lucas D. Bowler, Timothy Broom, Sydney Shall
      Pages 189-193

    8. Role of Poly(ADP-Ribose) Polymerase in Ribosomal RNA Gene Transcription

      • Samson T. Jacob, Jane F. Mealey, Rabinder N. Kurl
      Pages 194-199

    9. ADP-Ribosylation of HeLa Chromosomal and Nuclear Proteins: Response to DNA Damage Caused by Chemical Mutagens

      • Kenneth W. Adolph
      Pages 200-205

    10. Poly(ADP-Ribose) Polymerase: DNA Complexes Visualized as Looped Structures by Electron Microscopy

      • Gérard Gradwohl, Josette Dunand, Alice Mazen, Gilbert de Murcia
      Pages 206-212

    11. Poly(ADP-Ribose) May Signal Changing Metabolic Conditions to the Chromatin of Mammalian Cells

      • Pius Loetscher, Rafael Alvarez-Gonzalez, Felix R. Althaus
      Pages 213-217
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Keywords

About this book

Current interest in NAD (Nicotinamide adenine dinucleotide) in biological systems focuses on its role in ADP-ribose transfer reactions. These appear to be fundamentally involved in the regulation of many physiological processes. The contributions in this monograph thus represent the range of research in the very active investigation of niacin metabolism. The major topics covered are: ??? - Enzymology of ADP-Ribosylation - ADP-Ribosylation and Chromatin Function - Carcinogenesis and Differentiation - NAD Metabolism and Chemotherapy - ADP-Ribosylation and Signal Transduction - Molecular Genetic Approaches to ADP-Ribosylation

Editors and Affiliations

  • Department of Biochemistry, Texas College of Osteopathic Medicine, Fort Worth, USA

    Myron K. Jacobson

  • Department of Medicine, Texas College of Osteopathic Medicine, Fort Worth, USA

    Elaine L. Jacobson

Bibliographic Information

  • Book Title: ADP-Ribose Transfer Reactions

  • Book Subtitle: Mechanisms and Biological Significance

  • Editors: Myron K. Jacobson, Elaine L. Jacobson

  • DOI: https://doi.org/10.1007/978-1-4615-8507-7

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag New York Inc. 1989

  • Softcover ISBN: 978-1-4615-8509-1Published: 11 January 2012

  • eBook ISBN: 978-1-4615-8507-7Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XVI, 527

  • Topics: Biochemistry, general

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