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Mammary Tumorigenesis and Malignant Progression

Advances in Cellular and Molecular Biology of Breast Cancer

  • Book
  • © 1994

Overview

Editors:
  1. Robert B. Dickson

    1. Lombardi Cancer Research Center, Georgetown University School of Medicine, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Marc E. Lippman

    1. Lombardi Cancer Research Center, Georgetown University School of Medicine, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Cancer Treatment and Research (CTAR, volume 71)

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Table of contents (18 chapters)

  1. Cancer Cell Adhesion, Migration, and Proteolysis

    1. Urokinase plasminogen activator (uPA) and its type 1 inhibitor (PAI-1): Regulators of proteolysis during cancer invasion and prognostic parameters in Breast cancer

      • Nils Brünner, Charles Pyke, Claus Holst Hansen, John Rømer, Jan Grøndahl-Hansen, Keld Danø
      Pages 299-309

  2. Rodent Model Systems of Breast Cancer

    1. Front Matter

      Pages 311-311
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    2. Molecular mechanisms of chemical carcinogenesis in rodent models

      • Katherine McKenzie, Saraswati Sukumar
      Pages 313-329

    3. Fgf-3, an oncogene in murine breast cancer

      • Clive Dickson, Vera Fantl
      Pages 331-343

  3. Back Matter

    Pages 345-361
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Keywords

About this book

The current volume represents the fourth over a period of five years in our series on Advances in the Cellular and Molecular Biology of Breast Cancer. The first three volumes were entitled Breast Cancer: Cellular and Molecular Biology, Regulatory Mechanisms in Breast Cancer, and Genes, Oncogenes, and Hormones, respectively. Throughout this series, we have tried to take a broad look at cutting-edge topics in basic science research into breast cancer. This attempt has resulted in a wide range of subject material, including rodent and human model systems, oncogenes, suppressor genes, growth factors, hormones, tumor-host interactions, and determinants of metastases. Since our last volume, research in breast cancer has continued to proceed at an explosive rate. We hope the current volume will provide the reader with some of the excitement felt by the editors and authors as we begin to understand this all-too-common disease. The first section of this book is devoted to the basic processes of proli­ feration, differentiation, and malignant progression of breast cancer. T.l. Anderson and W.R. Miller lead off with a detailed description of controls on proliferation in the normal human breast and in breast cancer. This chapter strongly emphasizes pathological aspects. The second chapter, by M.R. Stampfer and P. Yaswen, presents a corresponding viewpoint through a presentation of experiments with human mammary epithelial cells in culture. The second section of the book emphasizes the genetic basis for breast cancer onset and malignant progression. Chapter 3, by M.-C. King and S.

Editors and Affiliations

  • Lombardi Cancer Research Center, Georgetown University School of Medicine, USA

    Robert B. Dickson, Marc E. Lippman

Bibliographic Information

  • Book Title: Mammary Tumorigenesis and Malignant Progression

  • Book Subtitle: Advances in Cellular and Molecular Biology of Breast Cancer

  • Editors: Robert B. Dickson, Marc E. Lippman

  • Series Title: Cancer Treatment and Research

  • DOI: https://doi.org/10.1007/978-1-4615-2592-9

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1994

  • Hardcover ISBN: 978-0-7923-2647-2Published: 31 July 1994

  • Softcover ISBN: 978-1-4613-6109-1Published: 08 October 2012

  • eBook ISBN: 978-1-4615-2592-9Published: 06 December 2012

  • Series ISSN: 0927-3042

  • Series E-ISSN: 2509-8497

  • Edition Number: 1

  • Number of Pages: XIV, 361

  • Topics: Oncology

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