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The Translational Apparatus

Structure, Function, Regulation, Evolution

  • Book
  • © 1993

Overview

Editors:
  1. Knud H. Nierhaus

    1. Max–Planck-Institut für Molekulare Genetik, Berlin, Germany

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  2. François Franceschi

    1. Max–Planck-Institut für Molekulare Genetik, Berlin, Germany

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  3. Alap R. Subramanian

    1. Max–Planck-Institut für Molekulare Genetik, Berlin, Germany

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  4. Volker A. Erdmann

    1. Freie Universität Berlin, Berlin, Germany

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  5. Brigitte Wittmann-Liebold

    1. Max–Delbrück-Centrum für Molekulare Medizin, Berlin, Germany

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Table of contents (69 chapters)

  1. Translational Initiation and Termination

    1. The Central Pseudoknot Connecting the Three Major Domains in 16S rRNA is Required for Translational Initiation

      • Marcel F. Brink, Martin Ph. Verbeet, Herman A. de Boer
      Pages 209-220

    2. RNA Helicase Activity in Translation Initiation in Eukaryotes

      • Arnim Pause, Nahum Sonenberg
      Pages 221-228

    3. Translation Initiation by Internal Ribosome Binding of Eukaryotic mRNA Molecules

      • Chang-You Chen, Dennis G. Macejak, Soo-Kyung Oh, Peter Sarnow
      Pages 229-240

    4. Novel Structural and Functional Aspects of Translational Initiation Factor IF2

      • Roberto Spurio, Manuela Severini, Anna La Teana, Maria A. Canonaco, Roman T. Pawlik, Claudio O. Gualerzi et al.
      Pages 241-252

    5. Translational Stop Signals: Evolution, Decoding for Protein Synthesis and Recoding for Alternative Events

      • Warren P. Tate, Frances M. Adamski, Chris M. Brown, Mark E. Dalphin, Jason P. Gray, Jules A. Horsfield et al.
      Pages 253-262

  2. The Elongation Process: Sites, Factors, Nascent Chain

    1. The Allosteric Three-Site Model and the Mechanism of Action of Both Elongation Factors EF-Tu and EF-G

      • Knud H. Nierhaus, Reinald Adlung, Thomas-Peter Hausner, Susanne Schilling-Bartetzko, Tomasz Twardowski, Francisco Triana
      Pages 263-272

    2. Elongation Factor Tu from Thermus Thermophilus, Structure, Domains and Interactions

      • Mathias Sprinzl, Rolf Hilgenfeld
      Pages 273-284

    3. Topography of the Ternary EF-Tu/GTP/Phe-tRNAPhe Complex as Studied by Crosslinking and Limited Proteolysis

      • Joseph Reinbolt, Marie-Hélène Metz, Pascale Romby, Bernard Ehresmann, Chantal Ehresmann
      Pages 285-294

    4. Specific Functions of Elongation Factor Tu, a Molecular Switch in Protein Biosynthesis, as Studied by Site-Directed Mutagenesis

      • Albert Weijland, Kim Harmark, Pieter H. Anborgh, Andrea Parmeggiani
      Pages 295-304

    5. EF-Tu Stoichiometries in Code Translation

      • Måns Ehrenberg, Neşe Bilgin, Judith Scoble
      Pages 305-315

    6. Kinetic Fluorescence Study on EF-Tu-Dependent Binding of Phe-tRNAPhe to the Ribosomal a Site

      • Marina V. Rodnina, Rainer Fricke, Wolfgang Wintermeyer
      Pages 317-326

    7. Defining the Function of EF-3, a Unique Elongation Factor in Low Fungi

      • Francisco J. Triana, Knud H. Nierhaus, Jeffrey Ziehler, Kalpana Chakraburtty
      Pages 327-338

    8. Antibiotic and Protein Interactions with the Gtpase and Peptidyl Transferase Regions in 23S rRNA

      • Stephen Douthwaite, Birte Vester, Claus Aagaard, Gunnar Rosendahl
      Pages 339-346

    9. Extension and Folding of Nascent Peptides on Ribosomes

      • Boyd Hardesty, O. W. Odom, Wieslaw Kudlicki, Gisela Kramer
      Pages 347-358

    10. Protein Synthesis and Secretion as Seen by the Nascent Protein Chain

      • Arthur E. Johnson, Kathleen S. Crowley, Steven K. Shore, Gregory D. Reinhart
      Pages 359-370

  3. Accuracy in Translation

    1. Mutants of tRNA, Ribosomes and mRNA Affecting Frameshifting, Hopping or Stop Codon Read-Through

      • J. F. Atkins, K. Herbst, M. O’Connor, T. M. F. Tuohy, R. B. Weiss, N. M. Wills et al.
      Pages 371-374

    2. Use of Ribosomal Accuracy Mutants to Probe Mechanisms of Programmed Translational Frameshifts in Escherichia coli

      • John Sipley, Emanuel Goldman
      Pages 375-384

    3. 23S rRNA Tunes Ribosomal Accuracy

      • Neşe Bilgin, Måns Ehrenberg
      Pages 385-395

  4. Quaternary Structure, Functional Centers and Domains in the Ribosome

    1. Towards Atomic Resolution of Prokaryotic Ribosomes: Crystallographic, Genetic and Biochemical Studies

      • François Franceschi, Shulamith Weinstein, Ute Evers, Evelyn Arndt, Werner Jahn, Harly A. S. Hansen et al.
      Pages 397-410

    2. Functional Site Determinations in Three Dimensions on Eukaryotic and Eubacterial Ribosomes

      • Adriana Verschoor, Suman Srivastava, Michael Radermacher, Joachim Frank, Robert R. Traut, Marina Stöffler-Meilicke et al.
      Pages 411-419
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Keywords

Editors and Affiliations

  • Max–Planck-Institut für Molekulare Genetik, Berlin, Germany

    Knud H. Nierhaus, François Franceschi, Alap R. Subramanian

  • Freie Universität Berlin, Berlin, Germany

    Volker A. Erdmann

  • Max–Delbrück-Centrum für Molekulare Medizin, Berlin, Germany

    Brigitte Wittmann-Liebold

Bibliographic Information

  • Book Title: The Translational Apparatus

  • Book Subtitle: Structure, Function, Regulation, Evolution

  • Editors: Knud H. Nierhaus, François Franceschi, Alap R. Subramanian, Volker A. Erdmann, Brigitte Wittmann-Liebold

  • DOI: https://doi.org/10.1007/978-1-4615-2407-6

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1993

  • Hardcover ISBN: 978-0-306-44538-5Published: 31 December 1993

  • Softcover ISBN: 978-1-4613-6021-6Published: 21 January 2013

  • eBook ISBN: 978-1-4615-2407-6Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XIII, 746

  • Topics: Biochemistry, general, Cell Biology, Human Genetics, Animal Anatomy / Morphology / Histology, Plant Sciences

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