Overview
- Editors:
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Franco Celada
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University of Genoa, Genoa, Italy
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Verne N. Schumaker
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University of California, Los Angeles, USA
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Eli E. Sercarz
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University of California, Los Angeles, USA
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Table of contents (55 chapters)
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The Importance of Antigen Conformation for Antigenicity and Immunogenicity
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- Jay A. Berzofsky, Gail K. Buckenmeyer, Gloria Hicks, Douglas J. Killion, Ira Berkower, Yoichi Kohno et al.
Pages 165-180
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- Marc H. V. Van Regenmortel, Danièle Altschuh, Jean-Paul Briand
Pages 181-190
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The Changes in Protein Antigen Conformation Induced by Antibody
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- Franco Celada, Verne N. Schumaker, Eli E. Sercarz
Pages 211-212
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- Roberto S. Accolla, Renata Cina’, Elisabetta Montesoro, Franco Celada
Pages 213-216
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- Irving Zabin, Audrèe V. Fowler, Franco Celada
Pages 225-231
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- Roberto Strom, Jasna Radojkovic, Paola Minale, Franco Celada
Pages 233-241
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The Recognition By T Cells of Protein Antigens
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- Franco Celada, Verne N. Schumaker, Eli E. Sercarz
Pages 243-244
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Which are the Antigenic Determinants that T Cells Recognize?
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- David W. Thomas, Michael D. Hoffman, Kun-hwa Hsieh, George D. Wilner
Pages 247-259
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- David C. Benjamin, Lise A. Daigle, Richard L. Riley
Pages 261-280
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- Giampietro Corradin, Serge Carel, Yolande Buchmüller, Patrick Amiguet, Howard D. Engers, Claude Bron
Pages 281-287
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- Ira Berkower, Gail K. Buckenmeyer, Frank R. N. Gurd, Jay A. Berzofsky
Pages 289-300
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What is the Role of MHC and other Genes in the Antigen Presenting Cell?
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- C. Shirley Lin, Ted. H. Hansen, Lanny T. Rosenwasser, Brigitte T. Huber, Alan S. Rosenthal
Pages 303-313
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- Boris Rotman, Michael J. Depasquale
Pages 323-336
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- R. B. Taylor, C. A. Morrison
Pages 337-345
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Analysis of the Ternary Complex of Antigen: MHC: and T-Cell Receptor with T Cell Clones
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- E. Rüde, A. B. Reske-Kunz, E. Spaeth
Pages 349-358
About this book
This volume is the collection of papers presented during a four day meeting, the EMBO workshop "Protein Conformation as an Immunological Signal" that took place at Portovenere (La Spezia), Italy, October 1-4, 1981. The motivation that drove us to organize this meeting was the feeling that distinct groups of researchers, active in key areas of modern immunology, sometimes fail to communicate with each other simply because of different traditional affiliations. Yet it is urgent that "molecular" and "cellular" people cooperate more if immunology is to continue the exportation of new concepts to other disciplines. In fact, the deep meaning of molecule-molecule and cell-cell interaction, the generation of signals and their effective transmission which results in elicitation, control or suppression of responses cannot be unraveled without the experts on antibody structure or complement activation sharing their views with the experts on T cell, B cell and macrophage membrane receptors as well as the experts on factors that carry the information released by these cells. Whether the meeting was scientifically fruitful, the reader can judge after having digested these pages. We, the organizers, are not sure whether the optimal amount·of interaction had taken place; especially considering how hard it is to overcome the scientist's catch 22: You have to know something quite well before you get really interested in it. In any event, we are convinced that Portovenere was one of the most successful attempts we have witnessed.