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Mechanisms in Carcinogenesis and Cancer Prevention

  • Book
  • © 2003

Overview

Editors:
  1. Harri U. Vainio

    1. Unit of Chemoprevention, International Agency for Research on Cancer, Lyon, France

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    You can also search for this editor in PubMed   Google Scholar

  2. Eino K. Hietanen
    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 156)

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Table of contents (17 chapters)

  1. Front Matter

    Pages I-XXI
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  2. Causes of Cancer and Opportunities for Prevention

    • H. Vainio, E. Hietanen
    Pages 1-11

  3. Genetic and Environmental Factors in Carcinogenesis

    • K. Hemminki
    Pages 13-24

  4. Genetic Pathways to Human Cancer

    • H. Ohgaki, W. Yasui, J. Yokota
    Pages 25-39

  5. Signalling Pathways as Targets in Cancer Prevention

    • M. M. Manson, L. M. Howells, E. A. Hudson
    Pages 41-56

  6. TP53 in Carcinogenesis and Cancer Prevention

    • E. Gormally, P. Hainaut
    Pages 57-81

  7. Apoptosis

    • B. W. Stewart
    Pages 83-106

  8. Deficient DNA Mismatch Repair in Carcinogenesis

    • P. Peltomäki
    Pages 107-128

  9. Epigenetic Changes, Altered DNA Methylation and Cancer

    • F. Lyko
    Pages 129-140

  10. Hormonal Carcinogenesis

    • R. Kaaks
    Pages 141-167

  11. Angiogenesis: A Promising Target for Cancer Prevention

    • I. U. Ali
    Pages 169-185

  12. Arachidonic Acid Pathway in Cancer Prevention

    • G. J. Kelloff, C. C. Sigman
    Pages 187-210

  13. Infections, Inflammation and Cancer: Roles of Reactive Oxygen and Nitrogen Species

    • H. Ohshima, M. Tatemichi
    Pages 211-227

  14. Infections and the Etiology of Human Cancer: Epidemiological Evidence and Opportunities for Prevention

    • F. X. Bosch, S. de Sanjosé, J. Ribes, C. A. González
    Pages 229-251

  15. Xenobiotic Metabolism and Cancer Susceptibility

    • O. Pelkonen, K. Vähäkangas, H. Raunio
    Pages 253-269

  16. Animal Models for Mechanistic Cancer Research

    • Zhao-Qi Wang
    Pages 271-288

  17. New Promising Chemopreventive Agents and Mechanisms

    • C. Gerhäuser, N. Frank
    Pages 289-305

  18. Molecular Epidemiology in Cancer Prevention

    • C. P. Wild
    Pages 307-321

  19. Back Matter

    Pages 323-329
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Keywords

About this book

A large proportion of cancers is preventable. External factors, discovered by epidemiological studies during the last 50 years, account for a majority of all cancer deaths. However, still rather little is known, about how environmental and genetic factors interact, how they may regulate gene activation etc. And it is a long way from the discovery of a basic regulatory mechanism to practical patient treatment. This volume describes the present state of the art in carcinogenesis, possibilities for cancer prevention, and gives genetic background in cancer development. Attention is given to the host-environment interaction, considering how this interaction may lead to cancer formation and how it can be utilised in cancer prevention. The molecular basis for cancer development and the molecular basis for prevention are described.

Editors and Affiliations

  • Unit of Chemoprevention, International Agency for Research on Cancer, Lyon, France

    Harri U. Vainio

Bibliographic Information

  • Book Title: Mechanisms in Carcinogenesis and Cancer Prevention

  • Editors: Harri U. Vainio, Eino K. Hietanen

  • Series Title: Handbook of Experimental Pharmacology

  • DOI: https://doi.org/10.1007/978-3-662-08602-5

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2003

  • Hardcover ISBN: 978-3-540-43837-3Published: 08 April 2003

  • Softcover ISBN: 978-3-642-07859-0Published: 01 December 2010

  • eBook ISBN: 978-3-662-08602-5Published: 17 April 2013

  • Series ISSN: 0171-2004

  • Series E-ISSN: 1865-0325

  • Edition Number: 1

  • Number of Pages: XXI, 329

  • Topics: Pharmacology/Toxicology, Oncology, Cancer Research, Molecular Medicine

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