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Adrenergic Activators and Inhibitors

Part I

  • Book
  • © 1980

Overview

Editors:
  1. Lászlo Szekeres

    1. Institute of Pharmacology, University Medical School of Szeged, Szeged, Hungary

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Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 54 / 1)

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Table of contents (21 chapters)

  1. Front Matter

    Pages I-XXVI
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  2. General Considerations

    1. Front Matter

      Pages 1-1
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    2. Chemistry of Alpha- and Beta-Adrenoceptor Agonists and Antagonists

      • D. K. Phillips
      Pages 3-61

    3. Sympathomimetic Amine-Induced Responses of Effector Organs Subserved by Alpha-, Beta1-, and Beta2-Adrenoceptors

      • A. Arnold
      Pages 63-88

    4. Evalution of Adrenergic Alpha- and Beta-Receptor Activators and Adrenergic Alpha- and Beta-Receptor Blocking Agents

      • P. N. Patil, R. R. Ruffolo Jr.
      Pages 89-134

    5. Evaluation of Agents That Release or Modify Release of Adrenergic Transmitter

      • J. M. Armstrong, A. F. Green
      Pages 135-221

    6. Catecholamine Receptors on Nerve Terminals

      • M. J. Rand, M. W. McCulloch, D. F. Story
      Pages 223-266

    7. Adrenergic Agents, Calcium Ions, and Cyclic Nucleotides in the Control of Cell Proliferation

      • J. F. Whitfield
      Pages 267-317

    8. Effects on the Metabolism

      • S. Ellis
      Pages 319-349

  3. Effects on the Autonomic and on the Central Nervous System

    1. Front Matter

      Pages 351-351
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    2. Presynaptic Receptors in the Autonomic Nervous System

      • J. S. Gillespie
      Pages 353-425

    3. Adrenergic Activators and Inhibitors on the Central Nervous System

      • A. Philippu
      Pages 427-427

    4. Regulation of Monoamine Synthesis and Utilization by Receptors

      • N.-E. Andén
      Pages 429-462

    5. Interactions of Opiates and Endorphins With Cerebral Catecholamines

      • J. Bläsig, A. Herz
      Pages 463-497

    6. Behavioural Pharmacology Reflecting Catecholamine Neurotransmission

      • U. Ungerstedt
      Pages 499-519

    7. Regulation of the Arterial Blood Pressure

      • A. Philippu
      Pages 521-548

    8. Catecholamines and the Regulation of Body Temperature

      • R. D. Myers
      Pages 549-567

    9. Regulation of Food Intake

      • J. F. Marshall
      Pages 569-578

    10. Regulation of Water Intake

      • D. K. Meyer, G. Hertting
      Pages 579-594

  4. Effects on the Cardiovascular System

    1. Front Matter

      Pages 595-595
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Keywords

About this book

Not much more than a decade has passed since the appearance of the outstanding handbook, Catecholamines, edited by BLASCHKO and MUSCHOLL, in the series: Handbook of Experimental Pharmacology. However, this extremely well organized volume dealt mainly with the origin, molecular actions, and fate of the naturally occuring catecholamines. It was felt that a separate volume should be dedicated to the remarkable and exciting progress made in the field of agents influencing the adrenergic system, both in physiologic and pharmacologic respect. The editor of the present volume considers himself lucky to have been able to persuade a number of eminent specialists to collaborate. The main concept of the present handbook is a systematic approach to the various effects of adrenergic activators and inhibitors starting with the chemistry and structure actitivity relationship, followed by the evaluation of adrenergic activators and inhibitors, and discussing their mode of action. The most voluminous part is the chapter dealing with the systemic pharma­ cology of these agents analyzing the effects on the central nervous system, on the autonomic nervous system, on the cardiovascular, the respiratory, the digestive, the endocrine system, on the skeletal muscle, and on metabolism. Kinetics and bio­ transformation, further toxic effects are discussed in the following chapters. A special chapter on clinical features concludes the monograph.

Editors and Affiliations

  • Institute of Pharmacology, University Medical School of Szeged, Szeged, Hungary

    Lászlo Szekeres

Bibliographic Information

  • Book Title: Adrenergic Activators and Inhibitors

  • Book Subtitle: Part I

  • Editors: Lászlo Szekeres

  • Series Title: Handbook of Experimental Pharmacology

  • DOI: https://doi.org/10.1007/978-3-642-67505-8

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1980

  • eBook ISBN: 978-3-642-67505-8Published: 06 December 2012

  • Series ISSN: 0171-2004

  • Series E-ISSN: 1865-0325

  • Edition Number: 1

  • Number of Illustrations: 34 b/w illustrations

  • Topics: Pharmacology/Toxicology, Pharmacy

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