Overview
- Editors:
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Jonathan J. Li
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Division of Etiology and Prevention of Hormonal Cancers, The University of Kansas Medical Center, Kansas City
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Sara A. Li
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Division of Etiology and Prevention of Hormonal Cancers, The University of Kansas Medical Center, Kansas City
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Antonio Llombart-Bosch
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Departmento de Patologia, Facultad de Medicina y Odontologia, Valencia, Spain
- Covers a group of hormonally-associated cancers that present interesting challenges to clinicians and biomedical researchers
- Addresses vital questions that impact our understanding of the causation, dependency, progression, resistance, and prevention of these types of cancers
- Includes supplementary material: sn.pub/extras
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Table of contents (58 chapters)
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Prostate I: Androgen/Estrogen Action
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Front Matter
Pages 181-181
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- Ronald K. Ross, Leigh Pearce, Juergen K. V. Reichardt, Gerhard A. Coetzee
Pages 183-196
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- Y C Wong, M T Ling, X H Wang, X S Ouyang, A L M Cheung, Franky L Chan
Pages 197-208
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Prostate II: Androgen Receptor: Dependence/Resistance
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Front Matter
Pages 209-209
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- Shutsung Liao, John M. Kokontis, Chih-pin Chuu, Stephen Hsu, Junichi Fukuchi, Mai Dang et al.
Pages 211-220
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- Zoran Culig, Hannes Steiner, Sonia Godoy-Tundidor, Barbara Comuzzi, Georg Bartsch, Alfred Hobisch
Pages 221-232
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- Haojie Huang, Donald J. Tindall
Pages 233-244
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Endometrium/Ovarian/Colon
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Front Matter
Pages 245-245
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- Karin Klinga-Levan, Göran Levan
Pages 247-257
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- Peter C. K. Leung, Kyung-Chul Choi, Nelly Auersperg
Pages 258-270
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Communications
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Front Matter
Pages 271-271
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Epidemiology/Human Derived Studies
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- Susan D. Reed, Lynda F. Voigt, Shirley A. Beresford, Deirdre A. Hill, Jennifer A. Doherty, Noel S. Weiss
Pages 273-276
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- Gertraud Maskarinec, Andrew E. Williams, Sabina Rinaldi, Rudolph Kaaks
Pages 277-286
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- Cristina Caraion, Nadine Vincent, Claude Lambert, Constantin Caraion, Guorong Li, Pierre Seffert et al.
Pages 287-292
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- Yu-Chuen Huang, Yi-Ping Shih, Chun-Chih Li, Li-Ying Liao, Yi-Ming A. Chen
Pages 293-299
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- Nicolas G. Azios, Suranganie F. Dharmawardhane
Pages 300-307
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- Simon J. Crook, J. David Brook, Anette Sommer, Joern Kraetzschmar, John F. R. Robertson
Pages 308-313
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- Maciej Skrzypczak, Sylwia Zagulska-Szymczak, Rosette Lidereau, Ivan Bieche, Sebastian Lewandowski, Katarzyna Radwanska et al.
Pages 314-320
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- Fernando Teba, Rocio MartÃn, Vicente Gómez, Luis SantamarÃa
Pages 329-335
About this book
It has been over a decade since the First International Symposium on Hormonal Carcinogenesis convened in 199 1. Since then, the field has rapidly expanded with considerable progress in both breast and prostate cancers; while ovarian and endometrial cancer have been hampered, in part, due to the absence of suitable hormone-mediated animal models. While knock-out, transgenic, and cell-culture systems have been extremely useful in identifying specific genelprotein alterations and the ensuing pathways affected, the precise molecular mechanisms whereby sex hormones elicit their oncogenic effects still remain elusive. Moreover, despite the considerable progress made in breast cancer research, the exact role of progestins in the presence or absence of estrogen in breast growth, differentiation, and malignant transformation is lacking. Elucidating the incipient molecular alterations in earlylpre-invasive lesions elicited by these hormones is a growing important focus of this field. The main purpose of these Symposia has been to address vital questions that impact our understanding of the causation, dependency, progression, resistance, and prevention of hormonally-associated cancers. We are indebted to the Scientific Advisory Board members who worked with us reviewing and offering suggestions to finalize the scientific program. We offer special thanks for the guidance and support of Dr. Gerald Mueller. His wisdom played an indispensable role in maintaining the excellence of these Symposia. We also acknowledge the numerous external reviewers that worked diligently to revise and improve the quality of the manuscripts. We are very grateful to Ms. Tandria Price.