Overview
- Editors:
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M.A. Hayat
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, Kean University, Room 213, Library building, Union, USA
- Epilepsy treatment and prognosis
- Symptoms of tumors in children
- Diagnostic imaging technology
- Differences between tumors in adults and children
- Color illustrations
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Table of contents (30 chapters)
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BRAIN TUMORS (GENERAL)
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- Anna Skowronska-Gardas, Marzanna Chojnacka, Katarzyna Pedziwiatr
Pages 183-197
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- Roberto Gaggero, Alessandro Consales, Francesca Fazzini, Maria Luisa Garrè, Pasquale Striano
Pages 199-206
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- R. Shane Tubbs, Martin M. Mortazavi, Aaron A. Cohen-Gadol
Pages 207-210
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- Donna L. Johnston, Daniel L. Keene
Pages 223-228
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- Sarah Hile, Erica Montague, Bonnie Carlson-Green, Paul Colte, Leanne Embry, Robert D. Annett
Pages 229-246
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- Eric Chow, Lillian Meacham
Pages 247-256
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Gliomas
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Front Matter
Pages 257-257
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GLIOMAS
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- Rishi R. Lulla, Jason Fangusaro
Pages 269-283
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- Robert Listernick, David H. Gutmann
Pages 285-294
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- Maura Massimino, Veronica Biassoni, Elisabetta Schiavello
Pages 309-320
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- Pinki K. Prasad, Elizabeth Yang
Pages 321-332
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Back Matter
Pages 333-352
About this book
A general introduction to the principles of diagnosis and treatment of children with brain tumors is presented. Molecular characterization of solid tumors is also presented. Molecular pathways provide putative targets for new therapies. High resolution magic spinning NMR spectroscopy is explained, which is used to determine metabolic profiles for small pieces of intact tissue and whole cells in culture. The differences between adult and pediatric brain tumors are outlined. It is emphasized that pediatric low-grade gliomas need lower doses of antidrugs such as cisplatin/etoposide. It is explained that tumor suppressor genes and oncogenes play a crucial role in the development and progression of human malignancies, including those in children. Neurofibromatosis type-1 is a common genetic disorder with a high prevalence in CNS abnormalities including tumors in children; which is discussed in detail. Various neuroradiological imaging modalities in children with leukemia are detailed. Also are detailed results of clinical trials in pediatric brain tumors, such as medulloblastoma, ependymoma, craniopharyngioma, low-grade glioma, high-grade glioma, brainstem glioma, and germ cell tumors, using radiotherapy. Considering the clinical importance of epilepsy in the primary brain tumors in children, its symptoms, diagnosis, and treatments (surgery and antiepileptic drugs) are discussed.
Editors and Affiliations
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, Kean University, Room 213, Library building, Union, USA
M.A. Hayat