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Infection Control in Intensive Care Units by Selective Decontamination

The Use of Oral Non-Absorbable and Parenteral Agents

  • Conference proceedings
  • © 1989

Overview

Editors:
  1. Hendrik K. F. Saene

    1. Medical Microbiology, Royal, Liverpool Hospital, Liverpool, UK

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  2. C. P. Stoutenbeek

    1. Intensieve Zorgen, Onze Lieve Vrouw Gasthuis, Amsterdam, The Netherlands

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  3. Peter Lawin

    1. Klinik für Anästhesiologie und operative Intensivmedizin, Westfälischen Wilhelms-Universität, Münster, Germany

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  4. I. McA. Ledingham

    1. The Faculty of Medicine, Health Sciences University, Al Ain, United Arab Emirates

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Part of the book series: Update in Intensive Care and Emergency Medicine (UICM, volume 7)

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Table of contents (57 papers)

  1. An Alternative Approach — Selective Decontamination of the Digestive Tract (SDD); the Use of Non-absorbable and Parenteral Agents

    1. Role of Endotoxin

      1. Discussion
        • Hendrik K. F. van Saene, C. P. Stoutenbeek, Peter Lawin, I. McA. Ledingham
        Pages 143-144

    2. Emergence of Resistance during SDD

      1. Cefotaxime Combined with Selective Decontamination in Long-term Intensive Care Unit Patients: Virtual Absence of Emergence of Resistance
        • H. K. F. van Saene, C. P. Stoutenbeek, D. F. Zandstra
        Pages 146-153
      2. Emergence of Resistance during Selective Decontamination: Glasgow Results
        • A. T. Eastaway
        Pages 154-154
      3. Changes in Antibiotic Resistance in Tracheal Aspirates Following Selective Decontamination of the Digestive Tract
        • M. Sydow, H. Burchardi, T. A. Crozier, R. Rüchel, C. Busse, W. Seyde
        Pages 155-155
      4. The Liverpool Experience, 1987–1988
        • A. E. Murray
        Pages 156-157
      5. Colonization and Resistance Patterns of Microbial Isolates following SDD in Association with Short-course Cefotaxime
        • K. Heeg, K. Bigos, F. Konrad, H. Wiedeck, H. Wagner
        Pages 158-158
      6. Gram-negative Bacillary Resistance in a Surgical Intensive Care Unit: A Four-Year Surveillance
        • E. A. E. Verhage, A. J. H. Kerver, J. H. Rommes
        Pages 159-159
      7. Discussion
        • Hendrik K. F. van Saene, C. P. Stoutenbeek, Peter Lawin, I. McA. Ledingham
        Pages 160-162

  2. Stress Ulcer Prophylaxis and Pneumonia

    1. Front Matter

      Pages 163-163
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    2. Stress Ulcer Prophylaxis and Pneumonia

      1. Pathogenesis of Stress Ulcer Bleeding in the Critically Ill
        • D. F. Zandstra, C. P. Stoutenbeek, H. M. Oudemans-van Straaten
        Pages 166-172
      2. Gastric Colonization and Nosocomial Pneumonia in the Mechanically Ventilated Patient
        • D. E. Craven
        Pages 173-183
      3. New Approaches to the Prevention of Infection in Intensive Care Unit Patients
        • J. Flaherty, S. A. Kabins, R. A. Weinstein
        Pages 184-188
      4. Discussion
        • Hendrik K. F. van Saene, C. P. Stoutenbeek, Peter Lawin, I. McA. Ledingham
        Pages 189-190

  3. Analysis of Conventional and SDD Approaches

    1. Front Matter

      Pages 191-191
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    2. A Possible Explanation for the Success of SDD

      • H. K. F. van Saene, C. P. Stoutenbeek, D. F. Zandstra
      Pages 193-196

    3. Discussion

      • Hendrik K. F. van Saene, C. P. Stoutenbeek, Peter Lawin, I. McA. Ledingham
      Pages 197-197

    4. Impact of Parenteral Cephalosporins on Human Oropharyngeal and Faecal Flora

      • J. C. Pechère
      Pages 198-202

    5. Discussion

      • Hendrik K. F. van Saene, C. P. Stoutenbeek, Peter Lawin, I. McA. Ledingham
      Pages 203-204

    6. Development of Antibiotic Resistance during Conventional and SDD

      • C. A. Hart
      Pages 205-210

    7. The Gut and Sepsis in the Critically Ill

      • J. R. Border
      Pages 211-213
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Keywords

About this book

Selective decontamination is a technique which combines short-term and long-term antimicrobials to prevent or treat the acquisition and subsequent carriage of microorganisms causing late colonization and infections. The antimicrobials are selective in that they leave the indigenous, mostly anaerobic flora more or less intact, whilst the effective decontamination provides a genuine breakthrough in the endogenous route of pathogenesis. The improvements in decontamination techniques presented here offer significant reduction in infection related morbidity and mortality among trauma patients.

Editors and Affiliations

  • Medical Microbiology, Royal, Liverpool Hospital, Liverpool, UK

    Hendrik K. F. Saene

  • Intensieve Zorgen, Onze Lieve Vrouw Gasthuis, Amsterdam, The Netherlands

    C. P. Stoutenbeek

  • Klinik für Anästhesiologie und operative Intensivmedizin, Westfälischen Wilhelms-Universität, Münster, Germany

    Peter Lawin

  • The Faculty of Medicine, Health Sciences University, Al Ain, United Arab Emirates

    I. McA. Ledingham

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