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Disease, Metabolism and Reproduction in the Toxic Response to Drugs and Other Chemicals

Proceedings of the European Society of Toxicology Meeting Held in Rome, March 28 – 30, 1983

  • Conference proceedings
  • © 1984

Overview

Editors:
  1. Philip L. Chambers

    1. Department of Pharmacology, Trinity College, University of Dublin, Dublin 2, Ireland

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  2. Paolo Preziosi

    1. Department of Pharmacology, Catholic University of the Sacred Heart, Rome, Italy

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    You can also search for this editor in PubMed   Google Scholar

  3. Claire M. Chambers

    1. Department of Pharmacology, Trinity College, University of Dublin, Dublin 2, Ireland

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Archives of Toxicology (TOXICOLOGY, volume 7)

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Table of contents (113 papers)

  1. Toxic Effects on the Male Reproductive System

    1. Morphological Changes Produced in Rat Testis by Anticancer Drugs

      • C. Hodel, R. A. Ettlin, A. Zschauer
      Pages 147-150

    2. Aspects of Testicular Toxicity Induced by Anticancer Drugs

      • R. A. Ettlin, R. Bechter, I. P. Lee, C. Hodel
      Pages 151-154

    3. Changes in Germinal Tissue and Leydig Cells Correlated with Ethanol Consumption in Males with and without Liver Disease

      • P. J. Karhunen, A. Penttilä, K. Liesto, A. Männikkö, M. Välimäki, M. Möttönen et al.
      Pages 155-158

    4. Testicular Effects of Some Xanthine Derivatives in the Rat

      • M. Dahlbäck, Å. Ryrfeldt
      Pages 159-163

    5. Effects of Daily High Doses of Paracetamol Given Orally During Spermatogenesis in the Rat Testes

      • A. Jacqueson, H. Semont, M. Thevenin, J.-M. Warnet, R. Prost, J. R. Claude
      Pages 164-166

    6. The Effects on the Rat Testis of Single Inhalation Exposures to Ethylene Glycol Monoalkyl Ethers, in Particular Ethylene Glycol Monomethyl Ether

      • D. M. Samuels, J. E. Doe, D. J. Tinston
      Pages 167-170

    7. Effects of an Indenopyridine Derivative, Compound 20–438, on Spermatogonial Stem Cells of the Rat

      • K. E. Suter
      Pages 171-173

    8. Monitoring Chemically Induced DNA Damage in the Germ Cells of Male Mice

      • R. R. Racine, B. P. Schmid
      Pages 174-176

    9. Accumulation of Toxic Metals in Male Reproduction Organs

      • B. R. G. Danielsson, L. Dencker, A. Lindgren, H. Tjälve
      Pages 177-180

  2. Metabolism and Toxicity

    1. Front Matter

      Pages 181-181
      Download chapter PDF

    2. Active Metabolites in Toxicology: The Role of Cytochrome P-448 and Flavoprotein Oxidases

      • D. V. Parke, C. Ioannides
      Pages 183-192

    3. The Role of Pharmacokinetics in the Design and Interpretation of Toxicological Studies

      • J. W. Daniel
      Pages 193-193

    4. Structural Characteristics of Compounds That can be Activated to Chemically Reactive Metabolites: Use for a Prediction of a Carcinogenic Potential

      • W. K. Lutz
      Pages 194-207

    5. Covalent Binding to Proteins as a Mechanism of Chemical Toxicity

      • C. Pantarotto, C. Blonda
      Pages 208-218

    6. Species Differences in Oxidative Drug Metabolism: Some Basic Considerations

      • S. G. Al-Dabbagh, R. L. Smith
      Pages 219-231

    7. Human Pharmacokinetics and Safety of Boric Acid

      • J. S. Schou, J. A. Jansen, B. Aggerbeck
      Pages 232-235

    8. The Influence of Paracetamol on the Hepatic Biosynthesis of Lecithin

      • J. Lohmann, U. Lessing, H. Schriewer, M. Clemens, U. Gerlach
      Pages 236-239

    9. Decreased Blood Levels of Ethanol and Acetaldehyde by S-Adenosyl-L-Methionine in Humans

      • C. Di Padova, R. Tritapepe, P. Rovagnati, M. Pozzoli, G. Stramentinoli
      Pages 240-242

    10. Metabolic Activation of 2-Aminofluorene in the Salmonella Mutagenicity Assay by Different S-9 Preparations

      • G. Cantelli Forti, M. E. Fracasso, P. Hrelia, R. Leone, M. S. Venturini, M. C. Guerra
      Pages 243-248

    11. Reduction of Covalent Binding of Aflatoxin B1 to Rabbit Liver DNA After Immunization Against this Carcinogen

      • M. Caviezel, A. P. Aeschbach, W. K. Lutz, C. Schlatter
      Pages 249-252
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Keywords

Editors and Affiliations

  • Department of Pharmacology, Trinity College, University of Dublin, Dublin 2, Ireland

    Philip L. Chambers, Claire M. Chambers

  • Department of Pharmacology, Catholic University of the Sacred Heart, Rome, Italy

    Paolo Preziosi

Bibliographic Information

  • Book Title: Disease, Metabolism and Reproduction in the Toxic Response to Drugs and Other Chemicals

  • Book Subtitle: Proceedings of the European Society of Toxicology Meeting Held in Rome, March 28 – 30, 1983

  • Editors: Philip L. Chambers, Paolo Preziosi, Claire M. Chambers

  • Series Title: Archives of Toxicology

  • DOI: https://doi.org/10.1007/978-3-642-69132-4

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1984

  • Softcover ISBN: 978-3-540-12452-8Published: 01 October 1984

  • eBook ISBN: 978-3-642-69132-4Published: 06 December 2012

  • Series ISSN: 0171-9750

  • Edition Number: 1

  • Number of Pages: XIV, 538

  • Number of Illustrations: 19 b/w illustrations

  • Topics: Pharmacology/Toxicology, Metabolic Diseases, Pharmacy, Endocrinology

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