Overview
Part of the book series: Journal of Neural Transmission. Supplementa (NEURALTRANS, volume 71)
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Table of contents (26 chapters)
Keywords
About this book
This book deals with basic and clinical aspects of monoamine oxidase (MAO) subtypes A and B highlighting its importance in neurological and psychiatric diseases. Consequently the therapeutic actions of MAO-A and -B inhibitors in Parkinson’s disease (PK) and depression are the focus of several chapters. As MAO is the basis of the development of the "oxidative stress hypothesis" of PD, several chapters are devoted to iron and iron-induced oxidative stress in various experimental studies and clinical conditions. Based on these findings, new compounds have been developed which not only block MAO, but are in addition, either inhibitors of acetylcholine esterase or have iron chelating properties. The aspect of "preclinical" and "clinical" neuro protection as well as MAO neuroprotection are additional topics covered in this book. MAO, iron and neuroprotection are seen in the framework of general anti Parkinson’s therapy with chapters on levodopa, dopaminergic receptor agonists and clinical issues.
Editors and Affiliations
Bibliographic Information
Book Title: Oxidative Stress and Neuroprotection
Editors: H. Parvez, P. Riederer
Series Title: Journal of Neural Transmission. Supplementa
DOI: https://doi.org/10.1007/978-3-211-33328-0
Publisher: Springer Vienna
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer-Verlag Vienna 2006
Hardcover ISBN: 978-3-211-33327-3Published: 15 September 2006
Softcover ISBN: 978-3-7091-1736-1Published: 28 November 2014
eBook ISBN: 978-3-211-33328-0Published: 26 December 2006
Series ISSN: 0303-6995
Edition Number: 1
Number of Pages: XIV, 264
Additional Information: Special edition of "Journal of Neural Transmission", Suppl. 71
Topics: Neurology