Overview
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 786)
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About this book
Gene regulatory networks play a vital role in organismal development and function by controlling gene expression. With the availability of complete genome sequences, several novel experimental and computational approaches have recently been developed which promise to significantly enhance our ability to comprehensively characterize these regulatory networks by enabling the identification of respectively their genomic or regulatory state components, or the interactions between these two in unprecedented detail. Divided into five convenient sections, Gene Regulatory Networks: Methods and Protocols details how each of these approaches contributes to a more thorough understanding of the composition and function of gene regulatory networks, while providing a comprehensive protocol on how to implement them in the laboratory. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.
Authoritative and accessible, Gene Regulatory Networks: Methods and Protocols aims to provide novices and experienced researchers alike with a comprehensive and timely toolkit to study gene regulatory networks from the point of data generation to processing, visualization, and modeling.
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Keywords
Table of contents (22 protocols)
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Mapping Protein-DNA Interactions
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Visualitzation of GRNs
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Modeling of GRNs
Editors and Affiliations
Bibliographic Information
Book Title: Gene Regulatory Networks
Book Subtitle: Methods and Protocols
Editors: Bart Deplancke, Nele Gheldof
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-61779-292-2
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2012
Hardcover ISBN: 978-1-61779-291-5Published: 22 September 2011
Softcover ISBN: 978-1-4939-5838-2Published: 23 August 2016
eBook ISBN: 978-1-61779-292-2Published: 23 September 2011
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XI, 446
Topics: Human Genetics, Gene Expression