Overview
- Editors:
-
-
Visith Thongboonkerd
-
Medical Molecular Biology Unit Office for Research and Development Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
- The first collection of applications of proteomics to analyze various human body fluids
- Provides basic principles and strategies for proteomic analysis of human body fluids
- Offers more details regarding methodologies and recent findings
Access this book
Other ways to access
Table of contents (24 chapters)
-
Proteomic Analysis of Specific Types of Human Body Fluids
-
Methods, Findings, applications, Perspectives, and Future Directions
-
- Troels Zakarias Kristiansen, Anirban Maitra, Akhilesh Pandey
Pages 399-414
-
- David Crettaz, Lynne Thadikkaran, Denis Gallot, Pierre-Alain Queloz, Vincent Sapin, Joël S. Rossier et al.
Pages 415-436
-
- Amedeo Conti, Maria Gabriella Giuffrida, Maria Cavaletto
Pages 437-451
-
-
- Benjamin Solomon, Mark W. Duncan
Pages 467-493
-
- Atsushi Minamoto, Ken Yamane, Tomoko Yokoyama
Pages 495-507
-
- Michael Walden, Stefan Wittke, Harald Mischak, Raymond C. Vanholder, The European Uremic Toxin Work Group (EUTox)
Pages 509-520
-
Back Matter
Pages 521-533
About this book
Rapid growth of the “proteomics” field during the past twelve years has c- tributed to significant advances in science. To date, proteomic technologies have been widely applied to examining various kinds of biological materials. Clinical proteomics is the concept of using proteomic techniques to evaluate the proteomes in clinical samples for biomarker discovery and for better understa- ing of normal physiology and pathogenic mechanisms of human diseases. Tra- lating the proteomic information to clinical practice may lead to the ultimate goals of earlier diagnosis, improved therapeutic outcome and successful prev- tion of diseases. Human body fluids are produced, secreted, and/or excreted from various tissues or organs. Major compositions of body fluids are water, organic s- stances and inorganic compounds. These compositions vary in each body fluid, making one’s function different from the others. Analyses of protein com- nents in individual fluids would increase current knowledge on the biology and physiology of various organ systems, and on the pathophysiology of diseases, which cause alterations in protein production, secretion, and/or excretion from the affected tissues or organs into the body fluids. Additionally, human body fluids are the main targets and valuable sources for biomarker discovery. As the high-throughput capability and applicability of proteomics for analyzing proteins in the body fluids have been already proven, these desires are most likely achievable by using proteomic technologies.
Editors and Affiliations
-
Medical Molecular Biology Unit Office for Research and Development Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
Visith Thongboonkerd