Overview
- Editors:
-
-
Vincenzo Zappia
-
Institute of Biochemistry of Macromolecules, University of Naples, Naples, Italy
-
Anthony E. Pegg
-
The Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, USA
Access this book
Other ways to access
Table of contents (67 chapters)
-
Polyamines in Plants
-
-
- Rodolfo Federico, Chiara Alisi, Alessandra Cona, Riccardo Angelini
Pages 617-623
-
Polyamines in Microorganisms
-
Front Matter
Pages 625-625
-
- Rowland H. Davis, Glenn R. Barnett, Janet L. Ristow
Pages 627-632
-
- Tairo Oshima, Nobuko Hamasaki, Taketoshi Uzawa
Pages 633-642
-
- U. Bachrach, L. Abu-Elheiga, Y. G. Assaraf, J. Golenser, D. T. Spira
Pages 643-650
-
-
-
Inhibitors of Polyamine Biosynthesis in Therapy
-
Front Matter
Pages 675-675
-
- Carl W. Porter, Raymond J. Bergeron
Pages 677-690
-
- Pierre S. Mamont, Nicole Claverie, Fritz Gerhart
Pages 691-706
-
- Prasad S. Sunkara, John H. Zwolshen, Nellikunja J. Prakash, Terry L. Bowlin
Pages 707-716
-
- Alan J. Bitonti, Peter P. McCann, Albert Sjoerdsma
Pages 717-726
-
- Peter P. McCann, Cyrus J. Bacchi, Alan J. Bitonti, Felipe Kierszenbaum, Albert Sjoerdsma
Pages 727-735
-
- Sylke Müller, R.-M. Wittich, R. D. Walter
Pages 737-743
-
- Jürgen Kusche, Rudolf Menningen, Lothar Leisten, Bernhard Krakamp
Pages 745-752
-
-
Back Matter
Pages 759-779
About this book
This book contains the scientific contributions presented at an International Symposium held in Sorrento, Italy, in June 1988 under the auspices of the University of Naples, the Italian Society of Biochemistry, and the National Research Council. The modern history of polyamines dates back to 1958 when the Tabors and Rosenthal first described the outlines of their biological synthesis. From then on, and particularly in the last ten years, a veri table explosion of Literature, characterized by thousands of papers, has witnessed the interest of the scientific community toward these molecules. Perhaps the old statement that "polyamines are molecules in search of a function" is no longer true today. A large number of effects exerted by these simple molecules are well known, and in many cases the mechanisms underlying these effects have been elucidated. The first section of the volume is entirely devoted to the enzymology and molecular biology of ornithine decarboxylase. Since its discovery by Gale more than forty years ago, this can be considered among the most widely studied enzymes in biology, and one of the most complex models in enzyme regulation. The mechanism of control of the enzyme activity at the transcriptional, post-transcriptional and post-translational levels, as well as the fine regulation by antizyme, are discussed in detail. The second group of contributions deals wi th AdoMet decarboxylase, propylamine transferase, polyamine oxidase and the other enzymes related to polyamine interconversion and regeneration.
Editors and Affiliations
-
Institute of Biochemistry of Macromolecules, University of Naples, Naples, Italy
Vincenzo Zappia
-
The Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, USA
Anthony E. Pegg