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Table of contents (21 chapters)
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Critical Issues Related to Specific Antianginal Agents
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Regulatory Aspects Related to the Evaluation of New Antianginal Agents
Keywords
About this book
Part I updates the pathophysiology, clinical presentation and prognosis of angina pectoris. Part II aims to `put in numbers' the symptoms and signs of myocardial ischemia, starting from a revision of the currently used parameters. It is extremely important to quantify the variability of the disease for the correct design of clinical trial, a subject dealt with in Part III, which also discusses some clinico-pharmacological aspects of therapy. Part IV is a critical review of the drugs currently used for the treatment of stable and unstable angina, and particularly considers some important unresolved issues concerning their use. The current FDA and EC guidelines for the evaluation of antianginal drugs are briefly discussed in Part V, giving clinical investigators insight into how antianginal drugs are evaluated by regulatory agencies and what is considered as proof of a valid efficacy/tolerability ratio.
Drug Evaluation in Angina Pectoris will assist discerning cardiologists, pharmacologists, and advanced students of cardiology as well as innovative pharmaceutical companies, all of whom need to understand what angina is, how to evaluate treatment, and how to judge the agents used in its treatment.
Bibliographic Information
Book Title: Drug Evaluation in Angina Pectoris
Editors: Diego Ardissino, Lionel H. Opie, Stefano Savonitto
Series Title: Developments in Cardiovascular Medicine
DOI: https://doi.org/10.1007/978-1-4615-2628-5
Publisher: Springer New York, NY
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eBook Packages: Springer Book Archive
Copyright Information: Springer Science+Business Media New York 1994
Hardcover ISBN: 978-0-7923-2897-1Published: 30 November 1994
Softcover ISBN: 978-1-4613-6127-5Published: 08 October 2012
eBook ISBN: 978-1-4615-2628-5Published: 06 December 2012
Series ISSN: 0166-9842
Edition Number: 1
Number of Pages: XVI, 262
Topics: Cardiology