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Molecular Mechanisms of Metal Toxicity and Carcinogenesis

  • Book
  • © 2001

Overview

Editors:
  1. Xianglin Shi

    1. Pathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Morgantown, USA

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  2. Vince Castranova

    1. Pathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Morgantown, USA

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  3. Val Vallyathan

    1. Pathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Morgantown, USA

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  4. William G. Perry

    1. Occupational Safety and Health Administration, Washington DC, USA

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Part of the book series: Developments in Molecular and Cellular Biochemistry (DMCB, volume 34)

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Table of contents (26 chapters)

  1. Review

    1. Effects of Glutathione on Chromium-induced DNA Crosslinking and DNA Polymerase Arrest

      • Travis O’Brien, Jian Xu, Steven R. Patierno
      Pages 173-182

  2. Mini Review

    1. Cell Apoptosis Induced by Carcinogenic Metals

      • Fei Chen, Val Vallyathan, Vince Castranova, Xianglin Shi
      Pages 183-188

    2. Gene Expression Profile in Response to Chromium-Induced Cell Stress in A549 Cells

      • Jianping Ye, Xianglin Shi
      Pages 189-197

    3. Cr (Vi) Increases Tyrosine Phosphorylation Through Reactive Oxygen Species-Mediated Reactions

      • Yong Qian, Bing-Hua Jiang, Daniel C. Flynn, Stephen S. Leonard, Suiwei Wang, Zhuo Zhang et al.
      Pages 199-204

    4. Molecular biology of nickel carcinogenesis

      • Max Costa, Jessica E. Sutherland, Wu Peng, Konstantin Salnikow, Limor Broday, Thomas Kluz
      Pages 205-211

    5. Model reactions of Cr (VI) with DNA mediated by thiol species

      • Dmitriy Krepkiy, William E. Antholine, Charles Myers, David H. Petering
      Pages 213-219

    6. On the mechanism of Cr (VI)-induced carcinogenesis: Dose dependence of uptake and cellular responses

      • Kejian Liu, John Husler, Jianping Ye, Stephen S. Leonard, Debbie Cutler, Fei Chen et al.
      Pages 221-229

  3. Back Matter

    Pages 231-242
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Keywords

About this book

During the last two decades, chemical and cellular studies have contributed enormously to our understanding of metal-induced carcinogenesis, and many hypotheses on the role of metals in pathophysiological processes have been investigated. In addition, new techniques are available to shed light on the mechanism of carcinogenesis in molecular terms. This conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis in September 2000 focused on the latest research in molecular mechanisms of metal-induced toxicity and carcinogenesis. The conference promoted a multidisciplinary investigative approach and included presentations from international experts on state-of-the-art information in this field.

Editors and Affiliations

  • Pathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Morgantown, USA

    Xianglin Shi, Vince Castranova, Val Vallyathan

  • Occupational Safety and Health Administration, Washington DC, USA

    William G. Perry

Bibliographic Information

  • Book Title: Molecular Mechanisms of Metal Toxicity and Carcinogenesis

  • Editors: Xianglin Shi, Vince Castranova, Val Vallyathan, William G. Perry

  • Series Title: Developments in Molecular and Cellular Biochemistry

  • DOI: https://doi.org/10.1007/978-1-4615-0793-2

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Kluwer Academic Publishers 2001

  • Hardcover ISBN: 978-0-7923-7498-5Published: 31 December 2001

  • Softcover ISBN: 978-1-4613-5242-6Published: 15 December 2012

  • eBook ISBN: 978-1-4615-0793-2Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: VII, 242

  • Topics: Biochemistry, general

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