Extended! eBooks from the 'Springer Archives' only $8.99 each–save now!

Middle Molecular Strategy

Flow Synthesis to Functional Molecules

Editors: Fukase, Koichi, Doi, Takayuki (Eds.)

Free Preview
  • Explains how to design and synthesize bioactive and functional middle-size molecules
  • Describes the synthesis of structurally complex middle-size molecules
  • Shows how to utilize recently developed methods based on flow chemistry
see more benefits

Buy this book

eBook $129.00
price for USA in USD
  • ISBN 978-981-16-2458-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-981-16-2457-5
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
About this book

This book highlights recently discovered aspects of “middle-size molecules,” focusing on (1) their unique bio-functions on the basis of derivatives and conjugates of natural products, saccharides, peptides, and nucleotides; (2) the synthesis of structurally complex natural products; (3) special synthetic methods for π-conjugated functional molecules; and (4) novel synthetic methods using flow chemistry. Given its scope, the book is of interest to industrial researchers and graduate students in the fields of organic chemistry, medicinal chemistry, and materials science. 

About the authors

Koichi Fukase graduated from the Department of Chemistry, Osaka University, in 1982 and received his Ph.D. from Osaka University (under Prof. Tetsuo Shiba) in 1987. After spending 1 year as a JSPS Postdoctoral Fellow (under Prof. Shiba), he was appointed as Assistant Professor (1988–1996) at the Department of Chemistry, School of Science, Osaka University (under Prof. Shoichi Kusumoto). In 1994, he joined Prof. W. Clark Still’s group at Columbia University as a Ministry of Education Research Fellow. After returning to Osaka in 1995, he was promoted to Lecturer (1996) and Associate Professor (1998) and became Full Professor at the Department of Chemistry, Graduate School of Science, Osaka University, in 2004. He received the Chemical Society of Japan Award for Creative Work in 2011. His research interests include carbohydrate chemistry and glycobiology, synthetic organic chemistry, bio-imaging, and innate immunity.

Takayuki Doi received his Ph.D. from Tokyo Tech in 1991 (under Prof. Takashi Takahashi). After a postdoctoral scientist position under Prof. Gilbert Stork at Columbia University, he joined Tokyo Tech as Assistant Professor in 1993 and became Associate Professor in 2001. He was promoted to Full Professor at the Graduate School of Pharmaceutical Sciences, Tohoku University, in 2008 and joined the Graduate School of Life Sciences in 2018. He received the Progress Award in Synthetic Organic Chemistry, Japan in 2000, and the Pharmaceutical Society of Japan Award for Divisional Scientific Promotions in 2013.

Table of contents (19 chapters)

Table of contents (19 chapters)
  • Conjugation Strategies for Development of Bioactive Middle Molecules

    Pages 3-20

    Manabe, Yoshiyuki (et al.)

  • Total Synthesis, Biological Evaluation, and 3D Structural Analysis of a Cyclodepsipeptide Natural Product

    Pages 21-34

    Doi, Takayuki

  • Development of Middle-Size Molecules for Alkylation to Higher-Order Structures of Nucleic Acids

    Pages 35-53

    Nagatsugi, Fumi (et al.)

  • In Situ Synthesis of Glycoconjugates on the Cell Surface: Selective Cell Imaging Using Low-Affinity Glycan Ligands

    Pages 55-75

    Nomura, Shogo (et al.)

  • Chemical Approach Toward Controlling of Transient Protein Interactions

    Pages 77-96

    Ohkanda, Junko

Buy this book

eBook $129.00
price for USA in USD
  • ISBN 978-981-16-2458-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-981-16-2457-5
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Loading...

Services for this Book

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Middle Molecular Strategy
Book Subtitle
Flow Synthesis to Functional Molecules
Editors
  • Koichi Fukase
  • Takayuki Doi
Copyright
2021
Publisher
Springer Singapore
Copyright Holder
The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
eBook ISBN
978-981-16-2458-2
DOI
10.1007/978-981-16-2458-2
Hardcover ISBN
978-981-16-2457-5
Edition Number
1
Number of Pages
X, 357
Number of Illustrations
180 b/w illustrations, 101 illustrations in colour
Topics