Overview
- Provides an overview of protein-protein interactions (PPI)
- Classifies protein complexes and provides structural as well as mechanistic insights into formation of protein complexes
- Highlights the computational and experimental approaches to study PPI
- Helps readers understand the thermodynamics and kinetics involved in PPI
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Table of contents (6 chapters)
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Front Matter
Keywords
About this book
Further, it offers structural and mechanistic insights into the formation of protein-protein complexes and maps different PPIs into networks to delineate various pathways that operate at the cellular level. Lastly, it describes computational protein-protein docking techniques and discusses their implications for further experimental research. Given its scope, this book is a valuable resource for students, researchers, scientists, entrepreneurs, and medical/healthcare professionals.
Authors and Affiliations
About the authors
Dr. Krishna Mohan Poluri is currently working as an Associate Professor at the Biotechnology Department, IIT-Roorkee. He completed his PhD at Tata Institute of Fundamental Research TIFR-Mumbai, and Postdoc at Rutgers University & the University of Texas Medical Branch (UTMB-Texas). His areas of expertise are protein biochemistry & biophysics, bio-molecular interactions, structural biology, glycoimmunology, bionanotechnology, and algal biotechnology. He has published more than 110 articles and editorials in various respected international journals, books and book chapters. He is also a guest editor/editorial board member for several international research journals. He won numerous awards and fellowships for his research work including; young scientist awards from the Indian Science Congress Association (ISCA) in 2009, and National Academy of Sciences India (NASI) in 2014, and the DBT Innovative Young Biotechnologist Award (IYBA) in 2013.
Dr. Khushboo Gulati holds a PhD in Protein Biophysics from the Department of Biotechnology, Indian Institute of Technology (IIT), Roorkee. She completed her bachelor’s in Bioinformatics and master’s in Biotechnology at Punjab Panjab University, India. Her research interests are in the area of protein-protein interactions, protein engineering, molecular biophysics, and structural biology. She has authored 18 peer-reviewed research articles in SCI indexed international journals, 6 book chapters and a book on protein engineering techniques. She is a recipient of the ICMR young scientist award.
Ms. Sharanya Sarkar is currently working as a Research Associate at the Mechanistic Biological Chemistry Laboratory, Department of Biotechnology, Indian Institute of Technology (IIT), Roorkee. She completed her master’s degree in Biotechnology from IIT Roorkee in 2019, and her bachelor’s in Microbiology from St. Xavier’s College, Calcutta, in 2017.
Bibliographic Information
Book Title: Protein-Protein Interactions
Book Subtitle: Principles and Techniques: Volume I
Authors: Krishna Mohan Poluri, Khushboo Gulati, Sharanya Sarkar
DOI: https://doi.org/10.1007/978-981-16-1594-8
Publisher: Springer Singapore
eBook Packages: Computer Science, Computer Science (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2021
Hardcover ISBN: 978-981-16-1593-1Published: 20 May 2021
Softcover ISBN: 978-981-16-1596-2Published: 21 May 2022
eBook ISBN: 978-981-16-1594-8Published: 19 May 2021
Edition Number: 1
Number of Pages: XVII, 346
Number of Illustrations: 3 b/w illustrations, 80 illustrations in colour
Topics: Bioinformatics, Proteomics, Protein Structure, Gene Expression