Overview
- Provides an overall picture of histone H3 mutations in various tumors
- Offers a state-of-the-art summary of advances made over the past 10 years in the emerging area of histone mutation
- Sheds new light on accurate diagnosis and treatment
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1283)
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Table of contents (7 chapters)
Keywords
About this book
This book highlights the advances made in the area over the past 10 years, and offers a state-of-the-art summary of epigenetic alternation, gene expression, protein structure, drug discovery, immunotherapy, and mouse modeling of histone H3 mutations in various tumors. Chiefly intended to provide researchers and graduate students with an overall picture of these mutations, it will also be of interest to researchers in basic oncology, clinical oncology, and epigenetics, as well as academics and clinical oncology practitioners.
Editors and Affiliations
About the editors
Junhong Han, Ph.D. is a Primary Investigator at the State Key Laboratory of Biotherapy, Sichuan University. He is also a Professor at the West China School of Medicine and a member of the Cancer Center at West China Hospital, Sichuan University. His main research interests are in the areas of DNA replication, epigenetic modifications in genome stability, and cancer epigenetics. Currently, Dr. Han is also working to identify and analyze the genes, pathways, and networks involved in cancer chemoresistance, and to understand the transcriptional heterogeneity for pancreatic ductal adenocarcinoma primary tumor with metastasis. Dr. Han received his Ph.D. in Cell Biology from Tokyo Institute of Technology, Japan and completed his post-doctoral training at the Mayo Clinic in Rochester, Minnesota, USA.
Bibliographic Information
Book Title: Histone Mutations and Cancer
Editors: Dong Fang, Junhong Han
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-981-15-8104-5
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2021
Hardcover ISBN: 978-981-15-8103-8Published: 07 November 2020
Softcover ISBN: 978-981-15-8106-9Published: 07 November 2021
eBook ISBN: 978-981-15-8104-5Published: 06 November 2020
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: VII, 96
Number of Illustrations: 2 b/w illustrations, 15 illustrations in colour
Topics: Cancer Research, Gene Expression, Protein Science