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'Essentials of Cancer Genomic, Computational Approaches and Precision Medicine

  • Describes the role of omics in precision medicine for cancer therapies

  • Provides comprehensive and in-depth information on genomics, transcriptomics, pharmacogenomics, and translational oncology research

  • Explores the application of computational and biostatistical approaches in cancer research

  • Discusses relevant case studies, current challenges, and future prospects of precision medicine in cancer treatment

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Table of contents (21 chapters)

  1. Front Matter

    Pages i-xviii
  2. Part II

    1. Front Matter

      Pages 141-141
    2. Genomic Instability and Cancer Metastasis

      • Hira Gull, Nosheen Masood
      Pages 143-153
    3. Adapting the Foreign Soil: Factors Promoting Tumor Metastasis

      • Ramish Riaz, Shah Rukh Abbas, Maria Shabbir
      Pages 171-196
  3. Part III

    1. Front Matter

      Pages 197-197
    2. MicroRNAs in Cancer: From Diagnosis to Therapeutics

      • Kanisha Shah, Rakesh M. Rawal
      Pages 199-236
    3. Metabolic and Enzyme Engineering for the Microbial Production of Anticancer Terpenoids

      • Suresh Chandra Phulara, Vikrant Singh Rajput, Bidyut Mazumdar, Ashish Runthala
      Pages 237-259
    4. Translational Research in Oncology

      • Asma Saleem Qazi, Samina Akbar, Rida Fatima Saeed, Muhammad Zeeshan Bhatti
      Pages 261-311
    5. Molecular Profiling of Breast Cancer in Clinical Trials: A Perspective

      • Saima Shakil Malik, Iqra, Nosheen Akhtar, Iffat Fatima, Zaineb Akram, Nosheen Masood
      Pages 313-332
  4. Part IV

    1. Front Matter

      Pages 333-333
  5. Part V

    1. Front Matter

      Pages 363-363
    2. Biostatistics in Clinical Oncology

      • Gaurav Roy, Atanu Bhattacharjee, Iqra Khan
      Pages 365-378

About this book

This book concisely describes the role of omics in precision medicine for cancer therapies. It outlines our current understanding of cancer genomics, shares insights into the process of oncogenesis, and discusses emerging technologies and clinical applications of cancer genomics in prognosis and precision-medicine treatment strategies.

It then elaborates on recent advances concerning transcriptomics and translational genomics in cancer diagnosis, clinical applications, and personalized medicine in oncology. Importantly, it also explains the importance of high-performance analytics, predictive modeling, and system biology in cancer research.

Lastly, the book discusses current and potential future applications of pharmacogenomics in clinical cancer therapy and cancer drug development.


Editors and Affiliations

  • Fatima Jinnah Women University, Rawalpindi, Pakistan

    Nosheen Masood, Saima Shakil Malik

About the editors

Dr. Nosheen Masood is currently working as an Assistant Professor at the Department of Biotechnology, Fatima Jinnah Women University, Rawalpindi, Pakistan. She completed her PhD in Human Molecular Genetics at the Department of Biosciences at COMSATS University, Islamabad, Pakistan . Her main research interests include molecular biology and cancer genetics, with a focus on epidemiological studies, risk assessment, genomic analysis, immunohistochemistry-based diagnostics and protein-protein interactions. She has been received various prestigious awards, notably, the Research Productivity Award 2014-2015 from the Pakistan Council of Science and Technology (PCST) category D, and Research Productivity Awards from COMSATS Institute of Information Technology for six consecutive years from 2010 to15. She has served as a reviewer for a number of international journals. She has teaching experience in biotechnology, molecular biology, comparative genomics, environmental biology, regulation of gene expression and molecular evolution.

She has published a number of research articles in respected, peer-reviewed international journals and authored or co-authored various book chapters.

Saima Shakil Malik is presently working as the Scientific Officer at Armed Forces Institute of Pathology, Rawalpindi, Pakistan. She has obtained her Ph.D. from the Department of Biotechnology, Fatima Jinnah Women University, Rawalpindi, Pakistan. Previously, she has worked as a visiting researcher at the School of Cellular and Molecular Medicine at University of Bristol, UK. Her research interests are focused on the cancer genetics and molecular diagnostics. She has teaching experience in biotechnology, molecular biology and biostatistics. She has numerous publications in internationally reputed journals and authored book chapters.

Bibliographic Information

  • Book Title: 'Essentials of Cancer Genomic, Computational Approaches and Precision Medicine

  • Editors: Nosheen Masood, Saima Shakil Malik

  • DOI: https://doi.org/10.1007/978-981-15-1067-0

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2020

  • Hardcover ISBN: 978-981-15-1066-3Published: 21 March 2020

  • Softcover ISBN: 978-981-15-1069-4Published: 21 March 2021

  • eBook ISBN: 978-981-15-1067-0Published: 20 March 2020

  • Edition Number: 1

  • Number of Pages: XVIII, 499

  • Number of Illustrations: 9 b/w illustrations, 50 illustrations in colour

  • Topics: Cancer Research, Oncology, Human Genetics, Bioinformatics, Nanotechnology and Microengineering

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access