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Advances in Experimental Medicine and Biology

Structural Immunology

Editors: Jin, Tengchuan, Yin, Qian (Eds.)

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  • Presenting a comprehensive overview of important immune molecules and their structure-function relationships
  • Providing researchers and students with the latest research advances concerning the structural biology of some key immune molecules/pathways
  • Offering immunologists essential insights into how these immune molecules function
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eBook $89.00
price for USA in USD (gross)
  • ISBN 978-981-13-9367-9
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  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $159.99
price for USA in USD
  • ISBN 978-981-13-9366-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book presents a comprehensive overview of important immune molecules and their structure-function relationships. The immune system is highly complex, consisting of a network of molecules, cells, tissues and organs, and the immune reaction is involved in various physiological as well as pathological processes, including development, self-tolerance, infection, immunity, and cancer. Numerous molecules participate in immune recognition, inhibition and activation, and these important immune molecules can be roughly divided into cell surface receptors, intracellular receptors and intracellular signaling molecules. The study of how these immune molecules function at molecular level has laid the foundation for understanding the immune system. The book provides researchers and students with the latest research advances concerning the structural biology of key immune molecules/pathways, and offers immunologists essential insights into how these immune molecules function.


About the authors

Dr. Tengchuan Jin is a Professor at the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China (USTC). He holds a Ph.D. degree from the Illinois Institute of Technology and completed his postdoctoral training at the Laboratory of Immunology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), USA. His current research interests include the structural biology of the innate immune receptors, structure and function of inflammasome, molecular mechanism of microbe-host interactions, protein engineering and antibody drug development, and he has published more than 50 research articles in these fields.

Dr. Yin Qian is currently an Assistant Professor at the Department of Biological Science, Florida State University. She received her Ph.D. degree from Cornell University and completed her postdoctoral training at Cornell University and Harvard Medical School under Prof. Hao Wu, a well-known structural immunologist. Dr. Qian's research interests include the activation mechanism of interferon-inducible GTPases and regulatory mechanisms of Rag GTPases in autophagy. She has published a series of high-profile research articles in the field of structural immunology.

Table of contents (10 chapters)

Table of contents (10 chapters)
  • Structural Basis for Signaling Through Shared Common γ Chain Cytokines

    Pages 1-19

    Yang, Huilin (et al.)

  • MHC Molecules, T cell Receptors, Natural Killer Cell Receptors, and Viral Immunoevasins—Key Elements of Adaptive and Innate Immunity

    Pages 21-62

    Jiang, Jiansheng (et al.)

  • Structures of Immune Checkpoints: An Overview on the CD28-B7 Family

    Pages 63-78

    Liu, Weifeng (et al.)

  • Interleukin-10 Family Cytokines Immunobiology and Structure

    Pages 79-96

    Wei, Huaxing (et al.)

  • Structural Insights into the Interleukin-17 Family Cytokines and Their Receptors

    Pages 97-117

    Liu, Shenping

Buy this book

eBook $89.00
price for USA in USD (gross)
  • ISBN 978-981-13-9367-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $159.99
price for USA in USD
  • ISBN 978-981-13-9366-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Structural Immunology
Editors
  • Tengchuan Jin
  • Qian Yin
Series Title
Advances in Experimental Medicine and Biology
Series Volume
1172
Copyright
2019
Publisher
Springer Singapore
Copyright Holder
Springer Nature Singapore Pte Ltd.
eBook ISBN
978-981-13-9367-9
DOI
10.1007/978-981-13-9367-9
Hardcover ISBN
978-981-13-9366-2
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XIII, 226
Number of Illustrations
2 b/w illustrations, 84 illustrations in colour
Topics