Advances in Experimental Medicine and Biology

Periostin

Editors: Kudo, Akira (Ed.)

Free Preview
  • Elucidates the role of periostin in a wide range of diseases
  • Examines functions of periostin related to stemness
  • Explores use of periostin as a biomarker
  • Promotes research into new treatments
see more benefits

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-981-13-6657-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-981-13-6656-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book provides a comprehensive and up-to-date review of current understanding of periostin and its importance for human health and disease. Periostin is a secretory matricellular protein that has been revealed to play key roles in fibrillogenesis and cell migration, including metastasis of cancer cells. The production of periostin is upregulated during fibrotic responses and the mechanisms by which it promotes fibrosis have become a focus of interest owing to the potential clinical benefit to be derived from periostin blockade. In this book, readers will find coverage of all aspects, from the basic properties of periostin and its function as a scaffold for assembly of extracellular proteins through to its roles in bone and tissue regeneration, tumorigenesis, myocardial infarction, inflammatory and immune system disorders, and other diseases. Readers will also find the latest information on functions of periostin related to stemness and the application of periostin as a biomarker. It is hoped that the detailed knowledge of periostin and its pathobiological significance provided in this book will aid in the search for effective treatments for currently incurable diseases.

About the authors

Dr. Akira Kudo, Professor, Tokyo Institute of Technology, Japan

Table of contents (19 chapters)

Table of contents (19 chapters)
  • Naming, History, Future

    Pages 3-4

    Kudo, Akira

  • The Structure of the Periostin Gene, Its Transcriptional Control and Alternative Splicing, and Protein Expression

    Pages 7-20

    Kudo, Akira

  • Periostin Functions as a Scaffold for Assembly of Extracellular Proteins

    Pages 23-32

    Kii, Isao

  • Periostin Reexpression in Heart Disease Contributes to Cardiac Interstitial Remodeling by Supporting the Cardiac Myofibroblast Phenotype

    Pages 35-41

    Dixon, Ian M. C. (et al.)

  • Periostin in Bone Biology

    Pages 43-47

    Kudo, Akira

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-981-13-6657-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-981-13-6656-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Periostin
Editors
  • Akira Kudo
Series Title
Advances in Experimental Medicine and Biology
Series Volume
1132
Copyright
2019
Publisher
Springer Singapore
Copyright Holder
Springer Nature Singapore Pte Ltd.
eBook ISBN
978-981-13-6657-4
DOI
10.1007/978-981-13-6657-4
Hardcover ISBN
978-981-13-6656-7
Series ISSN
0065-2598
Edition Number
1
Number of Pages
VIII, 213
Number of Illustrations
8 b/w illustrations, 40 illustrations in colour
Topics