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Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules

The Shape of Organic Synthesis to Come

Editors: Kobayashi, Yuichi (Ed.)

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  • Presents a quick survey of topics in organic synthesis for top researchers, young chemists, graduate students, and those looking for new research based on organic chemistry 
  • Suggests future research based on organic synthesis   
  • Enables understanding of the purpose and major results of the contents with schemes and illustrations 
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eBook $79.99
price for USA in USD (gross)
  • ISBN 978-981-13-6244-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.99
price for USA in USD
  • ISBN 978-981-13-6243-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book describes cutting-edge organic syntheses of biologically active compounds, isolation of pharmaceutically promising compounds from microorganisms, drug design, and progress on chemical biology. Synthetic strategy and tactics are summarized for super-carbon chain compounds, antitumor polycycles, aryl C-glycoside, antimycins, duocarmycins, cannabinoids, and other compounds. Special chapters are devoted to synthesis and biochemistry of fatty acid metabolites, which play a central role in the initiation and resolution of inflammation. The book provides a quick survey of trending topics in organic synthesis and chemical tools for biological investigation, and furnishes ideas for future research in organic synthesis. In addition, the contents can easily be understood by young chemists, graduate students, and those who are looking for new research based on organic chemistry.


About the authors

Yuichi KOBAYASHI received Ph.D. from the Tokyo Institute of Technology in 1981. His supervisors were Professors Jiro Tsuji and Fumie Sato at the Tokyo Institute of Technology and Gibert Stork at Columbia University. He is a full Professor at Tokyo Institute of Technology. His research interests include organic synthesis using transition metal catalysts and developments of chiral C–C bond formation. Targets include fatty acid metabolites known as resolvins and leukotrienes, isoprostanes, epi-jasmonates, tetrahydrocannabinoids, cinchona alkaloids, phoslactomycins, etc. The picolinoxy leaving group in allylic substitution has created tertially and quaternary carbons. These achievements have been published in internationally renowned journals such as Angew. Chem. Int. Ed., Org. Lett., Nature, Chem. Eur. J. He has 35 years of teaching experience at the Tokyo Institute of Technology. 

Table of contents (14 chapters)

Table of contents (14 chapters)
  • Microbial Fraction Library: A Screening Source for Drug Discovery

    Pages 1-20

    Nogawa, Toshihiko (et al.)

  • Efficient Total Synthesis of Ōmura Natural Products

    Pages 21-47

    Sunazuka, Toshiaki (et al.)

  • Enantioselective Total Synthesis of the Antitumor Polycyclic Natural Products FR182877 and Taxol

    Pages 49-73

    Nakada, Masahisa

  • Synthetic Approaches on the Pluramycin-Class Antibiotics

    Pages 75-100

    Ando, Yoshio (et al.)

  • Recent Progress on the Total Synthesis of Duocarmycins A and SA, Yatakemycin, and PDE-I and PDE-II

    Pages 101-124

    Sakata, Juri (et al.)

Buy this book

eBook $79.99
price for USA in USD (gross)
  • ISBN 978-981-13-6244-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.99
price for USA in USD
  • ISBN 978-981-13-6243-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules
Book Subtitle
The Shape of Organic Synthesis to Come
Editors
  • Yuichi Kobayashi
Copyright
2019
Publisher
Springer Singapore
Copyright Holder
Springer Nature Singapore Pte Ltd.
eBook ISBN
978-981-13-6244-6
DOI
10.1007/978-981-13-6244-6
Hardcover ISBN
978-981-13-6243-9
Edition Number
1
Number of Pages
XXV, 355
Number of Illustrations
279 b/w illustrations, 127 illustrations in colour
Topics