Target Organ Toxicology in Caenorhabditis elegans

Authors: Wang, Dayong

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  • Broadens readers’ understanding to the toxicology in C. elegans
  • Provides a comprehensive introduction to target organ toxicology in C. elegans
  • Focusing on the intestinal and epidermal barriers and toxicity induction of environmental toxicants or stresses in the intestine, epidermis, neurons, muscle, and reproductive organs
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eBook $149.00
price for USA in USD (gross)
  • ISBN 978-981-13-6010-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-981-13-6009-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book introduces readers to intestinal and epidermal barriers, and to toxicity induction of environmental toxicants or stresses in the intestine, epidermis, neurons, muscle, and reproductive organs in Caenorhabditis elegans. In addition, it discusses the protective responses of various organs and nematodes’ avoidance behaviour with regard to environmental toxicants or stresses. The intestinal, epidermal, neuronal, and germline signalling pathways required for the regulation of toxicity of environmental toxicants or stresses are also introduced and discussed.

As a classic model animal with well-described genetic and developmental backgrounds, the nematode Caenorhabditis elegans has been successfully and widely used in both toxicity assessments and toxicological studies on various environmental toxicants and stresses. Once exposure to certain environmental toxicants has occurred, the toxicants can enter into the primary targeted organs (such as intestinal cells), and even be translocated into secondary targeted organs (such as reproductive organs and neurons). Based on related available data, this book provides a systematic understanding of target organ toxicology in C. elegans.

About the authors

Dr. Dayong Wang is a professor at the Medical School, Southeast University, China. He obtained his Ph.D. from Peking University in 2001 and completed his post-doctoral training at the University of Toronto from 2002 to 2004. His research focuses on toxicology and pathology using Caenorhabditis elegans as a model animal, fields in which he has published more than 160 research articles.

Table of contents (11 chapters)

Table of contents (11 chapters)
  • Protective Responses of Different Organs to Environmental Toxicants or Stresses

    Wang, Dayong

    Pages 1-25

  • Avoidance Behavior of Nematodes to Environmental Toxicants or Stresses

    Wang, Dayong

    Pages 27-69

  • Intestinal Barrier for Nematodes Against Toxicity of Environmental Toxicants or Stresses

    Wang, Dayong

    Pages 71-95

  • Epidermal Barrier for Nematodes Against Toxicity of Environmental Toxicants or Stresses

    Wang, Dayong

    Pages 97-122

  • Toxicity Induction in the Intestine and Epidermis in Nematodes Exposed to Environmental Toxicants or Stresses

    Wang, Dayong

    Pages 123-146

Buy this book

eBook $149.00
price for USA in USD (gross)
  • ISBN 978-981-13-6010-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-981-13-6009-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Target Organ Toxicology in Caenorhabditis elegans
Authors
Copyright
2019
Publisher
Springer Singapore
Copyright Holder
Springer Nature Singapore Pte Ltd.
eBook ISBN
978-981-13-6010-7
DOI
10.1007/978-981-13-6010-7
Hardcover ISBN
978-981-13-6009-1
Edition Number
1
Number of Pages
XIII, 337
Number of Illustrations
57 b/w illustrations, 175 illustrations in colour
Topics