Open Access This content is freely available online to anyone, anywhere at any time.

Alternatives to Animal Testing

Proceedings of Asian Congress 2016

Editors: Kojima, Hajime, Seidle, Troy, Spielmann, Horst (Eds.)

Free Preview
  • This is an Open Access book
  • Provides ​recent research on alternative to animal testings
  • Discusses the future approaches to  alternatives in 3Rs
  • Presents the highly selected contents in the Asian Congress on Alternatives and Animal Use in the Life Sciences
see more benefits

Buy this book

  • ISBN 978-981-13-2447-5
  • The ebook is not yet available online.
Hardcover n/a
  • ISBN 978-981-13-2446-8
  • Free shipping for individuals worldwide
About this book

This open access book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs. The book is based on the most informative contributions delivered at the Asian Congress 2016 on Alternatives and Animal Use in the Life Sciences. It will be of value for those working in R&D, for graduate students, and for educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare. The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0.

About the authors

Hajime Kojima

National Institute of Health Sciences , Kawasaki, Kanagawa, Japan

Troy Seidle

Humane Society International , Montréal, QC, Canada

Horst Spielmann

Institut für Pharmazie Free University of Berlin, Berlin, Germany

Table of contents (15 chapters)

Table of contents (15 chapters)
  • Zebrafish, Danio Rerio as a Replacement Alternative Model Useful in CKDu Experiments

    Pages 1-7

    Gunatilake, Mangala

  • Testing Method Development and Validation for in Vitro Skin Irritation Testing (SIT) by Using Reconstructed Human Epidermis (RhE) Skin Equivalent - EPiTRI®

    Pages 8-19

    Lin, Yu-Chun (et al.)

  • Development the Technique for the Preparation and Characterization of Reconstructed Human Epidermis (RHE)

    Pages 20-32

    Setijanti, Herlina B. (et al.)

  • Alternative Research (3Rs) in the World, Asia and Japan

    Pages 33-36

    Kurosawa, Tsutomu Miki

  • Approaches to Reducing Animal Use for Acute Toxicity Testing: Retrospective Analyses of Pesticide Data

    Pages 37-49

    Strickland, Judy (et al.)

Buy this book

  • ISBN 978-981-13-2447-5
  • The ebook is not yet available online.
Hardcover n/a
  • ISBN 978-981-13-2446-8
  • Free shipping for individuals worldwide

Recommended for you


Bibliographic Information

Bibliographic Information
Book Title
Alternatives to Animal Testing
Book Subtitle
Proceedings of Asian Congress 2016
  • Hajime Kojima
  • Troy Seidle
  • Horst Spielmann
Springer Singapore
Copyright Holder
The Editor(s) (if applicable) and The Author(s)
eBook ISBN
Hardcover ISBN
Edition Number
Number of Pages
VI, 130
Number of Illustrations
7 b/w illustrations, 39 illustrations in colour