Overview
- Discusses new knowledge gained through a multidisciplinary biophysical approach
- Describes emerging biophysical techniques in detail
- Discusses up-to-date applications in glycobiophysics
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1104)
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About this book
This book presents state of the art biophysical approaches to issues in glycobiology that have cutting-edge applications. Despite the importance of glycosylation, the complexity, heterogeneity, and flexibility of the glycans have inhibited their study. Each chapter in this book explains very recent significant advances in biophysical approaches through the use of techniques such as NMR spectroscopy, mass spectrometry, single-molecule imaging, X-ray crystallography, high-speed atomic force microscopy, and computational simulation and their integrative application. Concrete examples are provided of the value of these techniques in addressing key problems in the field. In addition, significant functional glycobiological issues are considered. For example, glycolipids can form dynamic clusters on cell membranes and provide platforms for molecules involved in cell recognition and subsequent signal transduction. The detailed delineation of these molecular systems is discussed, revealing their structural complexity and ability to assemble transiently. This timely book will be of value for graduate students and postdocs interested in frontier topics in glycoscience and also for senior bio-researchers in academic and industrial fields.
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Keywords
Table of contents (13 chapters)
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Front Matter
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Back Matter
Editors and Affiliations
About the editors
Yoshiki Yamaguchi, PhD
Synthetic Cellular Chemistry Laboratory
RIKEN Cluster for Pioneering Research
Koichi Kato, PhD
Exploratory Research Center on Life and Living Systems
National Institutes of Natural Sciences
Bibliographic Information
Book Title: Glycobiophysics
Editors: Yoshiki Yamaguchi, Koichi Kato
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-981-13-2158-0
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2018
Hardcover ISBN: 978-981-13-2157-3Published: 08 December 2018
eBook ISBN: 978-981-13-2158-0Published: 27 November 2018
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: XIII, 277
Number of Illustrations: 36 b/w illustrations, 74 illustrations in colour
Topics: Biochemistry, general, Biological and Medical Physics, Biophysics