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Advances in Experimental Medicine and Biology

Glycobiophysics

Editors: Yamaguchi, Yoshiki, Kato, Koichi (Eds.)

  • Discusses new knowledge gained through a multidisciplinary biophysical approach
  • Describes emerging biophysical techniques in detail
  • Discusses up-to-date applications in glycobiophysics
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eBook $119.00
price for USA in USD (gross)
  • ISBN 978-981-13-2158-0
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $159.99
price for USA in USD
  • ISBN 978-981-13-2157-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book presents state of the art biophysical approaches to issues in glycobiology that have cutting-edge applications. Despite the importance of glycosylation, the complexity, heterogeneity, and flexibility of the glycans have inhibited their study. Each chapter in this book explains very recent significant advances in biophysical approaches through the use of techniques such as NMR spectroscopy, mass spectrometry, single-molecule imaging, X-ray crystallography, high-speed atomic force microscopy, and computational simulation and their integrative application. Concrete examples are provided of the value of these techniques in addressing key problems in the field. In addition, significant functional glycobiological issues are considered. For example, glycolipids can form dynamic clusters on cell membranes and provide platforms for molecules involved in cell recognition and subsequent signal transduction. The detailed delineation of these molecular systems is discussed, revealing their structural complexity and ability to assemble transiently. This timely book will be of value for graduate students and postdocs interested in frontier topics in glycoscience and also for senior bio-researchers in academic and industrial fields.


About the authors

  Yoshiki Yamaguchi, PhD

Synthetic Cellular Chemistry Laboratory

RIKEN Cluster for Pioneering Research


  Koichi Kato, PhD
Exploratory Research Center on Life and Living Systems
National Institutes of Natural Sciences


Table of contents (13 chapters)

  • Effects of N-Glycans on Glycoprotein Folding and Protein Dynamics

    Amazaki, Yoko (et al.)

    Pages 1-19

  • Synthesis of Glycosylated Metal Complexes for Probing Carbohydrate-Carbohydrate Interactions

    Hasegawa, Teruaki

    Pages 21-39

  • Unraveling of Lipid Raft Organization in Cell Plasma Membranes by Single-Molecule Imaging of Ganglioside Probes

    Suzuki, Kenichi G. N. (et al.)

    Pages 41-58

  • MALDI Mass Spectrometry Imaging of N-Linked Glycans in Tissues

    Drake, Richard R. (et al.)

    Pages 59-76

  • Isomeric Separation and Characterisation of Glycoconjugates

    Alagesan, Kathirvel (et al.)

    Pages 77-99

Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-981-13-2158-0
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $159.99
price for USA in USD
  • ISBN 978-981-13-2157-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Glycobiophysics
Editors
  • Yoshiki Yamaguchi
  • Koichi Kato
Series Title
Advances in Experimental Medicine and Biology
Series Volume
1104
Copyright
2018
Publisher
Springer Singapore
Copyright Holder
Springer Nature Singapore Pte Ltd.
eBook ISBN
978-981-13-2158-0
DOI
10.1007/978-981-13-2158-0
Hardcover ISBN
978-981-13-2157-3
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XIII, 277
Number of Illustrations
36 b/w illustrations, 74 illustrations in colour
Topics