Synthesis of Therapeutic Oligonucleotides

Editors: Obika, Satoshi, Sekine, Mitsuo (Eds.)

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  • Presents the latest knowledge on a range of topics relating to the synthesis of therapeutic oligonucleotides
  • Aims to provide novel insights and inspire fresh ideas in nucleic acid chemistry
  • Meets the needs of both established researchers and students new to the field
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eBook $129.00
price for USA in USD (gross)
  • ISBN 978-981-13-1912-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-981-13-1911-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book presents the latest knowledge on a broad range of topics relating to the synthesis of natural and artificial oligonucleotides with therapeutic potential. Nucleic acid-based therapeutics are attracting much attention, and numerous therapeutic oligonucleotides, such as antisense oligonucleotides, siRNAs, splice-switching oligonucleotides, and nucleic acid aptamers, are being evaluated in clinical trials for the treatment of a variety of diseases. Synthesis of Therapeutic Oligonucleotides covers a broad range of topics in the field that are of high relevance to researchers, including the synthesis of natural and chemically modified oligonucleotides, the development of novel nucleic acid analogs, industrial scale synthesis and purification of oligonucleotides, and important aspects of chemistry, manufacturing, and controls (CMC). The aim is to provide new insights and inspire fresh ideas in nucleic acid chemistry that may ultimately lead to novel concepts and techniques and the discovery of more effective nucleic acid drugs. The book will be of high value for both established researchers in the field and students intending to specialize in nucleic acid chemistry research.


About the authors

Satoshi Obika, Osaka University, Japan

Mitsuo Sekine, Tokyo Institute of Technology, Japan

Table of contents (16 chapters)

Table of contents (16 chapters)

Buy this book

eBook $129.00
price for USA in USD (gross)
  • ISBN 978-981-13-1912-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-981-13-1911-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Synthesis of Therapeutic Oligonucleotides
Editors
  • Satoshi Obika
  • Mitsuo Sekine
Copyright
2018
Publisher
Springer Singapore
Copyright Holder
Springer Nature Singapore Pte Ltd.
eBook ISBN
978-981-13-1912-9
DOI
10.1007/978-981-13-1912-9
Hardcover ISBN
978-981-13-1911-2
Edition Number
1
Number of Pages
VIII, 284
Number of Illustrations
173 b/w illustrations, 35 illustrations in colour
Topics