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  • © 2019

Retinal Optical Coherence Tomography Image Analysis

  • Focuses on computerized automatic analysis of clinical optical coherence tomography (OCT) images
  • Includes a wealth of examples of clinical OCT images for different retinal pathologies
  • Offers comprehensive and in-depth descriptions of state-of-the-art image analysis methods applied to OCT images

Part of the book series: Biological and Medical Physics, Biomedical Engineering (BIOMEDICAL)

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xi
  2. Clinical Applications of Retinal Optical Coherence Tomography

    • Haoyu Chen, Tingkun Shi, Danny Siu-Chun Ng
    Pages 1-25
  3. Fundamentals of Retinal Optical Coherence Tomography

    • Delia Cabrera DeBuc, Gábor Márk Somfai, Bo Wang
    Pages 27-37
  4. Speckle Noise Reduction and Enhancement for OCT Images

    • Zahra Amini, Raheleh Kafieh, Hossein Rabbani
    Pages 39-72
  5. Segmentation of OCT Scans Using Probabilistic Graphical Models

    • Fabian Rathke, Mattia Desana, Christoph Schnörr
    Pages 105-130
  6. Diagnostic Capability of Optical Coherence Tomography Based Quantitative Analysis for Various Eye Diseases and Additional Factors Affecting Morphological Measurements

    • Delia Cabrera DeBuc, Jing Tian, Andrea Szigeti, Erika Tátrai, Boglárka EnikÅ‘ Varga, Gábor Márk Somfai
    Pages 131-167
  7. Segmentation of Optic Disc and Cup-to-Disc Ratio Quantification Based on OCT Scans

    • Menglin Wu, Theodore Leng, Luis de Sisternes, Daniel L. Rubin, Qiang Chen
    Pages 193-209
  8. Choroidal OCT Analytics

    • Kiran Kumar Vupparaboina, Ashutosh Richhariya, Jay Chhablani, Soumya Jana
    Pages 211-241
  9. Layer Segmentation and Analysis for Retina with Diseases

    • Fei Shi, Weifang Zhu, Xinjian Chen
    Pages 243-279
  10. Segmentation and Visualization of Drusen and Geographic Atrophy in SD-OCT Images

    • Qiang Chen, Sijie Niu, Luis de Sisternes, Theodore Leng, Daniel L. Rubin
    Pages 281-344
  11. Back Matter

    Pages 381-385

About this book

This book introduces the latest optical coherence tomography (OCT) imaging and computerized automatic image analysis techniques, and their applications in the diagnosis and treatment of retinal diseases. Discussing the basic principles and the clinical applications of OCT imaging, OCT image preprocessing, as well as the automatic detection and quantitative analysis of retinal anatomy and pathology, it includes a wealth of clinical OCT images, and state-of-the-art research that applies novel image processing, pattern recognition and machine learning methods to real clinical data. It is a valuable resource for researchers in both medical image processing and ophthalmic imaging.

Editors and Affiliations

  • School of Electronic and Information Engineering, Soochow University, Suzhou, China

    Xinjian Chen, Fei Shi

  • Joint Shantou International Eye Center, Shantou University and the Chinese University of Hong Kong, Shantou, China

    Haoyu Chen

About the editors

Xinjian Chen, IEEE Senior Member, received his Ph.D. degree from the Institute of Automation, Chinese Academy of Sciences in 2006. After graduation, he worked on research projects with several prestigious groups: Microsoft Research Asia, Beijing, China (2006-2007); Medical Image Processing Group, University of Pennsylvania (2008-2009); Department of Radiology and Image Sciences, National Institutes of Health  (2009-2011); and Department of Electrical and Computer Engineering, University of Iowa  (2011-2012). In 2012, he joined the School of Electrical and Information Engineering, Soochow University where he serves as a Distinguished Professor and Director of Medical Image Processing, Analysis and Visualization Laboratory. Under his leadership, the laboratory has evolved with a strong group of 8 faculty members and 30 postgraduate students working towards PhD and MS programs. The laboratory has received more than 10 National and Provincial grants, including the prestigious Young Scientist grant with Xinjian as the PI from National Basic Research Program of China (973).

Dr. Chen is a recipient of the National Science Fund for Outstanding Young Scholars, China (2016), National One Thousand Young Talents Award, China (2012), Jiangsu Provincial High Level Creative Talents Award (2013), Jiangsu Provincial Peak Talents of Six Categories Award (2012), Beijing Science and Technology Advancement Award (2011), Chinese Academy of Sciences President Excellence Award (2006), Important Technology Innovation Award of China (2005), and National Technology Advancement Award of China (2004). His research interests include medical image processing and analysis, pattern recognition, machine learning, and their applications.

Dr. Chen has published more than 100 peer-reviewed papers in prestigious international journals and conferences including IEEE Transactions on Medical Imaging, IEEE Transactions on Biomedical Engineering, Medical Physics, IEEE Transactions Information Technology in Biomedicine, and Radiology, etc. He has served as Workshop Chair for MICCAI OMIA2014, Co-Chair for MICCAI OMIA2015, 2016, and 2017. He has also served as the Workshop Chair for International Medical Imaging Workshop at Suzhou 2013, 2014, 2015 and 2017. He has served as Associate Editor for IEEE Transactions on Medical Imaging, and IEEE Journal of Translational Engineering in Health and Medicine. He also holds 10 granted patents and 20 pending status patents.

Fei Shi received her bachelor’s degree in Information and Electronics Engineering from Zhejiang University and her Ph.D. in Electrical Engineering from the Polytechnic University, Brooklyn, New York in 2006. She is currently an assistant professor at School of Electronics and Information Engineering, Soochow University. Her research interests include medical image processing, pattern recognition and time–frequency analysis. She has published more than 40 papers in international journals and conferences.

Haoyou Chen received an M.B.B.S. from Sun Yat-sen University in 2002, and M.D. from Zhongshan Ophthalmic Center, Sun Yat-sen University in 2008. He is currently a Consultant and Professor at the Joint Shantou International Eye Center, Shantou University and the Chinese University of Hong Kong. His research interests include ocular imaging and eye genetics. He has published 83 articles in international peer-reviewed journals and contributed to 6 book chapters. Dr. Chen serves as an Associate Editor for BMC Ophthalmology, editorial board member for Clinical Ophthalmology, and on the program committee for the 8th, 9th, 10th, 11th International Symposium of Ophthalmology (Hong Kong), and the 1st and 2nd MICCAI Workshop on Ophthalmic Medical Image Analysis. He has received several academic awards including Asia-Pacific Academy of Ophthalmology Achievement Award, Publons Peer Review Award, Youth Investigator Award in the 13th International Symposium on Retinal degeneration and a travel grant to Asia-ARVO 2015.


Bibliographic Information

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access