Authors:
- Recognized as an outstanding Thesis by the Department of Chemistry, Seoul National University
- A concise introduction to widely used fluorophores
- Offers an interdisciplinary approach to unravel the details of a novel fluorophore
Part of the book series: Springer Theses (Springer Theses)
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Table of contents (4 chapters)
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Front Matter
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Back Matter
About this book
Organic fluorophores have been extensively used in the field of molecular biology owing to their excellent photophysical property, suitable cell permeability, and synthetic flexibility. Understanding of the structure-photophysical property relationship of a given fluorophore often paves the road to the development of valuable molecular probes to visualize and transcribe biological networks. In this thesis, respective chapters deal with molecular design, organic synthesis, structure-property analysis, and quantum-mechanical interpretation of unexplored family of indolizine-based molecules. This systematic exploration has led to rational development of a new microalgae lipid droplet probe, colorful bioorthogonal fluorogenic probes, and a bright mitochondrial probe, working underlive cell conditions.
Harnessing the optical properties of a given fluorophore has been an important topic for a couple of decades, both in industry and in academia. This thesis provides useful insights for the improvement and development of unique small fluorescent materials, or optical materials.
Keywords
Authors and Affiliations
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Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul, Korea (Republic of)
Youngjun Lee
About the author
Dr. Youngjun Lee is a member of CRI Center for Chemical Proteomics, Department of Chemistry, Seoul National University, Korea. He earned Ph.D. degree in organic chemistry at SNU in February 2018.
​Bibliographic Information
Book Title: Systematic Exploration of Indolizine-Based Small Fluorescent Molecules
Book Subtitle: Synthesis, Analysis and Application
Authors: Youngjun Lee
Series Title: Springer Theses
DOI: https://doi.org/10.1007/978-981-13-1645-6
Publisher: Springer Singapore
eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2018
Hardcover ISBN: 978-981-13-1644-9Published: 28 August 2018
Softcover ISBN: 978-981-13-4660-6Published: 23 December 2018
eBook ISBN: 978-981-13-1645-6Published: 16 August 2018
Series ISSN: 2190-5053
Series E-ISSN: 2190-5061
Edition Number: 1
Number of Pages: XXV, 187
Number of Illustrations: 107 b/w illustrations, 90 illustrations in colour
Topics: Biochemical Engineering, Bioorganic Chemistry, Biological and Medical Physics, Biophysics, Biomedical Engineering and Bioengineering, Applied Microbiology