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Advances in Experimental Medicine and Biology

Non-coding RNAs in Complex Diseases

A Bioinformatics Perspective

Editors: Li, X., Xu, J., Xiao, Y., Ning, S., Zhang, Y. (Eds.)

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  • Offers an in-depth and comprehensive review on current understanding of regulatory ncRNAs in complex diseases from the view of bioinformatics
  • Conveys state-of-the-art bioinformatics tools and methods for ncRNAs from computational detection, functional prediction, to their roles in disease
  • Provides important information on current progress in this fast-moving field of bioinformatics for regulatory ncRNAs
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  • ISBN 978-981-13-0719-5
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  • Due: October 15, 2018
  • ISBN 978-981-13-0718-8
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  • ISBN 978-981-13-4486-2
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About this book

This book offers an in-depth and comprehensive review on current understanding of regulatory ncRNAs in complex diseases from a view of bioinformatics. It conveys state-of-the-art bioinformatics tools and methods for ncRNAs from computational detection, functional prediction, to their roles in diseases. Computational methods used to investigate uncharacterised ncRNAs in diseases are mainly summarized in seven aspects: DNA variation of ncRNAs in diseases, prioritization of disease-related ncRNAs, dysregulation epigenetic factors that regulate ncRNA misexpression (DNA methylation and histone-modification), complex crosstalk across ncRNAs, ncRNAs acted as competing regulators to mediate the expression of protein-coding genes, non-coding RNAs mediated risk pathways,and their contributions to drug target predictions. The generally used data resources of ncRNAs are also listed in the end. This book provides important information on the current progress in the fast-moving fields of bioinformatics for regulatory ncRNAs. It provides a timely and useful reference for computational biologists, specifically with RNA interests, and other related areas.

Prof. Xia Li is a Professor and the Dean of College of Bioinformatics Science and Technology, Harbin Medical University, China. Dr. Yun Xiao, Dr. Juan Xu, Dr. Shangwei Ning and Dr. Yunpeng Zhang are from College of Bioinformatics Science and Technology, Harbin Medical University, China.




About the authors

Prof. Xia Li is a Professor and the Dean of College of Bioinformatics Science and Technology, Harbin Medical University, China. Dr. Yun Xiao, Dr. Juan Xu, Dr. Shangwei Ning and Dr. Yunpeng Zhang are from College of Bioinformatics Science and Technology, Harbin Medical University, China.

Table of contents (12 chapters)

Table of contents (12 chapters)
  • Non-coding RNA Resources

    Pages 1-7

    Ning, Shangwei (et al.)

  • Systematic Identification of Non-coding RNAs

    Pages 9-18

    Xiao, Yun (et al.)

  • Functional Characterization of Non-coding RNAs Through Genomic Data Fusion

    Pages 19-28

    Xiao, Yun (et al.)

  • Genomic-Scale Prioritization of Disease-Related Non-coding RNAs

    Pages 29-37

    Wang, Peng (et al.)

  • Genome-Wide Mapping of SNPs in Non-coding RNAs

    Pages 39-48

    Ning, Shangwei (et al.)

Buy this book

eBook $119.00
price for USA in USD
  • ISBN 978-981-13-0719-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $159.99
price for USA in USD
  • Customers within the U.S. and Canada please contact Customer Service at +1-800-777-4643, Latin America please contact us at +1-212-460-1500 (24 hours a day, 7 days a week). Pre-ordered printed titles are excluded from promotions.
  • Due: October 15, 2018
  • ISBN 978-981-13-0718-8
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
Softcover $159.99
price for USA in USD
  • ISBN 978-981-13-4486-2
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Non-coding RNAs in Complex Diseases
Book Subtitle
A Bioinformatics Perspective
Editors
  • Xia Li
  • Juan Xu
  • Yun Xiao
  • Shangwei Ning
  • Yunpeng Zhang
Series Title
Advances in Experimental Medicine and Biology
Series Volume
1094
Copyright
2018
Publisher
Springer Singapore
Copyright Holder
Springer Nature Singapore Pte Ltd.
eBook ISBN
978-981-13-0719-5
DOI
10.1007/978-981-13-0719-5
Hardcover ISBN
978-981-13-0718-8
Softcover ISBN
978-981-13-4486-2
Series ISSN
0065-2598
Edition Number
1
Number of Pages
X, 126
Number of Illustrations
5 b/w illustrations, 37 illustrations in colour
Topics

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