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Myotonic Dystrophy

Disease Mechanism, Current Management and Therapeutic Development

Editors: Takahashi, Masanori, Matsumura, Tsuyoshi (Eds.)

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  • Provides an overview while also connecting clinical and fundamental research achievements
  • Introduces the molecular mechanisms within each organ and the resultant clinical features, especially focusing on central nervous system
  • Addresses the latest topics such as research using patient-derived iPS cells and therapeutic research
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eBook $54.99
$109.00 (listprice)
price for USA in USD
valid through September 30, 2020
  • ISBN 978-981-13-0508-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $89.99
$179.99 (listprice)
price for USA in USD
valid through September 30, 2020
Softcover $69.99
$139.99 (listprice)
price for USA in USD
valid through September 30, 2020
About this book

This book provides an essential overview combining both clinical and fundamental research advances in myotonic dystrophy. The pathomechanism of myotonic dystrophy has long been unclear, but in the past decade, our understanding has shifted to a novel disease mechanism concept: “RNA disease”. Parallel to these advances in elucidating the pathophysiology, translational research is also progressing rapidly. The current challenge lies in assessing the effectiveness of treatment, and as such, there is a growing interest in observational studies of the disease’s various clinical symptoms.

The book introduces readers to the molecular mechanisms within each organ and the resultant clinical features, which are presented together. In particular, it focuses on the central nervous system, since the pathology of the brain (central nervous system manifestation) has rarely been addressed systematically and will pose a persistent challenge, even if therapies have greatly advanced in the future. In addition, the book addresses the latest developments, such as research using patient-derived iPS cells and therapeutic research.

Myotonic Dystrophy provides essential information for neurologists and researchers with an interest in muscle disease, including muscular dystrophy. Furthermore, since the disease involves various complications of the brain, heart, metabolism, etc., the book will be of great value to clinicians and researchers in the cardiovascular sciences, endocrinology, diabetes, dementia, and neuropsychology, as well as genetic specialists.

About the authors

Masanori P. Takahashi, M.D., Ph.D.

Department of Functional Diagnostic Science, Osaka University Graduate School of Medicine, Japan

Tsuyoshi Matsumura, M.D., Ph.D.

Department of Neurology, National Hospital Organization Toneyama National Hospital, Japan


Reviews

“This book is suitable for neuromuscular medicine subspecialists, healthcare providers involved in the care of myotonic dystrophy patients, and clinical basic science researchers. The book meets the needs of this audience. … This book stands out as an excellent reference on myotonic dystrophy.” (Eduardo De Sousa, Doody's Book Reviews, June 28, 2019)

Table of contents (13 chapters)

Table of contents (13 chapters)

Buy this book

eBook $54.99
$109.00 (listprice)
price for USA in USD
valid through September 30, 2020
  • ISBN 978-981-13-0508-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $89.99
$179.99 (listprice)
price for USA in USD
valid through September 30, 2020
Softcover $69.99
$139.99 (listprice)
price for USA in USD
valid through September 30, 2020
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Bibliographic Information

Bibliographic Information
Book Title
Myotonic Dystrophy
Book Subtitle
Disease Mechanism, Current Management and Therapeutic Development
Editors
  • Masanori Takahashi
  • Tsuyoshi Matsumura
Copyright
2018
Publisher
Springer Singapore
Copyright Holder
Springer Nature Singapore Pte Ltd.
eBook ISBN
978-981-13-0508-5
DOI
10.1007/978-981-13-0508-5
Hardcover ISBN
978-981-13-0507-8
Softcover ISBN
978-981-13-4436-7
Edition Number
1
Number of Pages
VIII, 214
Number of Illustrations
16 b/w illustrations, 42 illustrations in colour
Topics

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