Overview
Summarizes and enriches understanding of the novel aspects of nicotinic acetylcholine receptor (nAChR) functions in the CNS
Professionals and scholars alike will find it a handy up-to-date overview of basic and clinical studies of nAChRs for the treatment of neurodegenerative diseases
This Open Access Book has an interdisciplinary appeal and will engage scholars in field of drug innovation
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Table of contents (10 chapters)
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Front Matter
Keywords
About this book
This open access book presents the roles and mechanisms of signal transduction triggered by nicotinic acetylcholine receptors (nAChRs) stimulation in neuroprotection against toxic effects of risk factors of neurodegenerative diseases. Accumulating evidence suggests that nAChRs in the CNS play important roles not only in excitatory neurotransmission but also in neuronal survival and related functions. Neuroprotection mediated by nAChRs in neurodegenerative diseases such as Alzheimer's disease is the major topic of this book. In response to rapidly evolving areas in clinical and laboratory neuropharmacology and neurochemistry, this volume provides in-depth coverage of neuroprotection in basic research and future developments in the clinical application of effective neuroprotective strategies in neurodegenerative diseases. This work appeals to both basic and clinical researchers in several fields, such as neuroscience, neurology, and pharmacology.
Editors and Affiliations
About the editors
Akinori Akaike
Department of Pharmacology, Kyoto University, Japan
Shun Shimohama
Department of Neurology, Sapporo Medical University School of Medicine, Japan
Yoshimi Misu
Graduate School of Medicine, Yokohama City University, Japan
Bibliographic Information
Book Title: Nicotinic Acetylcholine Receptor Signaling in Neuroprotection
Editors: Akinori Akaike, Shun Shimohama, Yoshimi Misu
DOI: https://doi.org/10.1007/978-981-10-8488-1
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s) 2018
License: CC BY
Hardcover ISBN: 978-981-10-8487-4Published: 13 April 2018
Softcover ISBN: 978-981-13-4166-3Published: 30 January 2019
eBook ISBN: 978-981-10-8488-1Published: 04 April 2018
Edition Number: 1
Number of Pages: X, 191
Number of Illustrations: 38 b/w illustrations, 24 illustrations in colour
Topics: Neurosciences, Neurology, Pharmacology/Toxicology